Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78

Oncogene

Volumn 32, Issue 41, 2013, Pages 4921-4931

  Tsai, H Y ^a,b   Yang, Y F ^a,b   Wu, A T ^c,f   Yang, C J ^d   Liu, Y P ^e   Jan, Y H ^b   Lee, C H ^g   Hsiao, Y W ^b   Yeh, C T ^c,h   Shen, C N ^b,c   Lu, P J ^e   Huang, M S ^d   Hsiao, M ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b GENOMICS RESEARCH CENTER   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^e NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^h TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

apoptosis; GRP78; lung cancer; RRBP1; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; BINDING PROTEIN; CASPASE 3; CASPASE 7; CYCLINE; DEOXYGLUCOSE; DOXORUBICIN; GLUCOSE REGULATED PROTEIN 78; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; RETICULUM RIBOSOME BINDING PROTEIN 1; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER SURVIVAL; CANCER TISSUE; CARCINOGENICITY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DATA BASE; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA STABILITY; TISSUE MICROARRAY; TUMOR BIOPSY; TUMOR XENOGRAFT; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; DOXORUBICIN; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HEAT-SHOCK PROTEINS; HUMANS; INTRACELLULAR SPACE; LUNG NEOPLASMS; MALE; MAP KINASE KINASE 4; MICE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, SMALL INTERFERING; TUNICAMYCIN;

EID: 84883449148     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2012.514     Document Type: Article

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