Ligation of major histocompatability complex (MHC) class I molecules on human T cells induces cell death through PI-3 kinase-induced c-Jun NH2- terminal kinase activity: A novel apoptotic pathway distinct from Fas- induced apoptosis

Journal of Cell Biology

Volumn 139, Issue 6, 1997, Pages 1523-1531

  Skov, Søren ^a   Klausen, Pia ^a   Claesson, Mogens H ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; DNA; FAS ANTIGEN; INTERLEUKIN 1BETA CONVERTING ENZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; WORTMANNIN;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; ONCOGENE C JUN; PRIORITY JOURNAL; T LYMPHOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANTIBODIES; APOPTOSIS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL NUCLEUS; CYTOPLASM; DNA FRAGMENTATION; HETEROCHROMATIN; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; MAP KINASE KINASE 4; MICROSCOPY, ELECTRON; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES; TRANSFECTION;

EID: 0031455407     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.139.6.1523     Document Type: Article

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