메뉴 건너뛰기




Volumn 114, Issue 10, 2014, Pages 1623-1639

Genetically encoded Ca2+ indicators in cardiac myocytes

Author keywords

Calcium; Fluorescence resonance energy transfer; Gene transfer techniques; Myocytes, cardiac

Indexed keywords

CALCIUM; CALMODULIN; CIRCULAR PERMUTATED FLUORESCENT PROTEIN; FURA 2; PROTEIN; TROPONIN C; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; FLUORESCENT DYE;

EID: 84900871500     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.114.303475     Document Type: Review
Times cited : (52)

References (157)
  • 1
    • 0037049977 scopus 로고    scopus 로고
    • Cardiac excitation-contraction coupling
    • Bers DM. Cardiac excitation-contraction coupling. Nature. 2002;415:198-205
    • (2002) Nature , vol.415 , pp. 198-205
    • Bers, D.M.1
  • 2
    • 59849097814 scopus 로고    scopus 로고
    • Calcium, calpains, and cardiac hypertrophy: A new link
    • Heidrich FM, Ehrlich BE. Calcium, calpains, and cardiac hypertrophy: A new link. Circ Res. 2009;104:e19-e20
    • (2009) Circ Res , vol.104
    • Heidrich, F.M.1    Ehrlich, B.E.2
  • 3
    • 80052166536 scopus 로고    scopus 로고
    • Neuronal calcium sensor-1 promotes immature heart function and hypertrophy by enhancing Ca2+ signals
    • Nakamura TY, Jeromin A, Mikoshiba K, Wakabayashi S. Neuronal calcium sensor-1 promotes immature heart function and hypertrophy by enhancing Ca2+ signals. Circ Res. 2011;109:512-523
    • (2011) Circ Res , vol.109 , pp. 512-523
    • Nakamura, T.Y.1    Jeromin, A.2    Mikoshiba, K.3    Wakabayashi, S.4
  • 4
    • 79959780260 scopus 로고    scopus 로고
    • Abnormal calcium homeostasis: One mechanism in diastolic heart failure
    • Zile MR, Gaasch WH. Abnormal calcium homeostasis: One mechanism in diastolic heart failure. J Am Coll Cardiol. 2011;58:155-157
    • (2011) J Am Coll Cardiol , vol.58 , pp. 155-157
    • Zile, M.R.1    Gaasch, W.H.2
  • 5
    • 84865274587 scopus 로고    scopus 로고
    • Calcium release units in heart failure: That's about the size of it
    • Swift F, Christensen G. Calcium release units in heart failure: That's about the size of it. Cardiovasc Res. 2012;95:397-398
    • (2012) Cardiovasc Res , vol.95 , pp. 397-398
    • Swift, F.1    Christensen, G.2
  • 10
    • 0030087710 scopus 로고    scopus 로고
    • Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer
    • Heim R, Tsien RY. Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer. Curr Biol. 1996;6:178-182
    • (1996) Curr Biol , vol.6 , pp. 178-182
    • Heim, R.1    Tsien, R.Y.2
  • 11
    • 84981779372 scopus 로고
    • Intermolecular energy migration and fluorescence
    • Förster T. Intermolecular energy migration and fluorescence. Ann Phys. 1948;437:55-75
    • (1948) Ann Phys , vol.437 , pp. 55-75
    • Förster, T.1
  • 12
    • 0031011418 scopus 로고    scopus 로고
    • Detection in living cells of Ca2+- dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence
    • Romoser VA, Hinkle PM, Persechini A. Detection in living cells of Ca2+- dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. J Biol Cem. 1997;272:13270-13274
    • (1997) J Biol Cem , vol.272 , pp. 13270-13274
    • Romoser, V.A.1    Hinkle, P.M.2    Persechini, A.3
  • 14
    • 0035129282 scopus 로고    scopus 로고
    • A high signal-To-noise Ca(2+) probe composed of a single green fluorescent protein
    • Nakai J, Ohkura M, Imoto K. A high signal-To-noise Ca(2+) probe composed of a single green fluorescent protein. Nat Biotechnol. 2001;19:137-141
    • (2001) Nat Biotechnol , vol.19 , pp. 137-141
    • Nakai, J.1    Ohkura, M.2    Imoto, K.3
  • 15
    • 0035853040 scopus 로고    scopus 로고
    • Circularly permuted green fluorescent proteins engineered to sense Ca2+
    • Nagai T, Sawano A, Park ES, Miyawaki A. Circularly permuted green fluorescent proteins engineered to sense Ca2+. Proc Natl Acad Sci U S A. 2001;98:3197-3202
    • (2001) Proc Natl Acad Sci U S A. , vol.98 , pp. 3197-3202
    • Nagai, T.1    Sawano, A.2    Park, E.S.3    Miyawaki, A.4
  • 16
    • 84861131971 scopus 로고    scopus 로고
    • Fluorescent genetically encoded calcium indicators and their in vivo application
    • Jung G, ed Heidelberg: Springer
    • Gensch T, Kaschuba D. Fluorescent genetically encoded calcium indicators and their in vivo application. In: Jung G, ed. Fluorescent Proteins II. Heidelberg: Springer; 2012:125-162
    • (2012) Fluorescent Proteins II , pp. 125-162
    • Gensch, T.1    Kaschuba, D.2
  • 18
    • 33645232527 scopus 로고    scopus 로고
    • Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2
    • Tallini YN, Ohkura M, Choi BR, et al. Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proc Natl Acad Sci U S A. 2006;103:4753-4758
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , pp. 4753-4758
    • Tallini, Y.N.1    Ohkura, M.2    Choi, B.R.3
  • 20
    • 11144295222 scopus 로고    scopus 로고
    • Efficient and non-Toxic gene transfer to cardiomyocytes using novel generation amplicon vectors derived from HSV-1
    • Ferrera R, Cuchet D, Zaupa C, Revol-Guyot V, Ovize M, Epstein AL. Efficient and non-Toxic gene transfer to cardiomyocytes using novel generation amplicon vectors derived from HSV-1. J Mol Cell Cardiol. 2005;38:219-223
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 219-223
    • Ferrera, R.1    Cuchet, D.2    Zaupa, C.3    Revol-Guyot, V.4    Ovize, M.5    Epstein, A.L.6
  • 21
    • 80054949849 scopus 로고    scopus 로고
    • The evolution of heart gene delivery vectors
    • Wasala NB, Shin JH, Duan D. The evolution of heart gene delivery vectors. J Gene Med. 2011;13:557-565
    • (2011) J Gene Med , vol.13 , pp. 557-565
    • Wasala, N.B.1    Shin, J.H.2    Duan, D.3
  • 24
    • 0041669332 scopus 로고    scopus 로고
    • Semliki Forest virus vectors for gene therapy
    • Lundstrom K. Semliki Forest virus vectors for gene therapy. Expert Opin Biol Ther. 2003;3:771-777
    • (2003) Expert Opin Biol Ther , vol.3 , pp. 771-777
    • Lundstrom, K.1
  • 25
    • 4644318481 scopus 로고    scopus 로고
    • Lentiviral vectors: Optimization of packaging, transduction and gene expression
    • Delenda C. Lentiviral vectors: Optimization of packaging, transduction and gene expression. J Gene Med. 2004;6(suppl 1):S125-S138
    • (2004) J Gene Med , vol.6 , Issue.SUPPL1
    • Delenda, C.1
  • 26
    • 0033756217 scopus 로고    scopus 로고
    • Update on adenovirus and its vectors
    • Russell WC. Update on adenovirus and its vectors. J Gen Virol. 2000;81:2573-2604
    • (2000) J Gen Virol , vol.81 , pp. 2573-2604
    • Russell, W.C.1
  • 28
    • 0032146082 scopus 로고    scopus 로고
    • Cultured adult cardiac myocytes: Future applications, culture methods, morphological and electrophysiological properties
    • Mitcheson JS, Hancox JC, Levi AJ. Cultured adult cardiac myocytes: Future applications, culture methods, morphological and electrophysiological properties. Cardiovasc Res. 1998;39:280-300
    • (1998) Cardiovasc Res , vol.39 , pp. 280-300
    • Mitcheson, J.S.1    Hancox, J.C.2    Levi, A.J.3
  • 29
    • 65649083775 scopus 로고    scopus 로고
    • Adenovirus-mediated delivery of short hairpin RNA (shRNA) mediates efficient gene silencing in terminally differentiated cardiac myocytes
    • Rinne A, Littwitz C, Bender K, Kienitz MC, Pott L. Adenovirus-mediated delivery of short hairpin RNA (shRNA) mediates efficient gene silencing in terminally differentiated cardiac myocytes. Methods Mol Biol. 2009;515:107-123
    • (2009) Methods Mol Biol , vol.515 , pp. 107-123
    • Rinne, A.1    Littwitz, C.2    Bender, K.3    Kienitz, M.C.4    Pott, L.5
  • 32
    • 38049075791 scopus 로고    scopus 로고
    • A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes
    • Viero C, Kraushaar U, Ruppenthal S, Kaestner L, Lipp P. A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes. Cell Calcium. 2008;43:59-71
    • (2008) Cell Calcium , vol.43 , pp. 59-71
    • Viero, C.1    Kraushaar, U.2    Ruppenthal, S.3    Kaestner, L.4    Lipp, P.5
  • 33
    • 84893575037 scopus 로고    scopus 로고
    • Cardiac safety screens: Molecular, cellular and optical advancements
    • Lin CP, Ntziachistos V, eds. Munich: SPIE 80890H-1-80890H-6
    • Kaestner L, Tian Q, Lipp P. Cardiac safety screens: Molecular, cellular and optical advancements. In: Lin CP, Ntziachistos V, eds. Biomedical Optics III Vol. 8089. Munich: SPIE; 2011:80890H-1-80890H-6
    • (2011) Biomedical Optics III , vol.8089
    • Kaestner, L.1    Tian, Q.2    Lipp, P.3
  • 35
    • 40649121773 scopus 로고    scopus 로고
    • Gene-Therapy delivery strategies in cardiology
    • Müller OJ, Ksienzyk J, Katus HA. Gene-Therapy delivery strategies in cardiology. Future Cardiol. 2008;4:135-150
    • (2008) Future Cardiol , vol.4 , pp. 135-150
    • Müller, O.J.1    Ksienzyk, J.2    Katus, H.A.3
  • 36
    • 0033977926 scopus 로고    scopus 로고
    • Highefficiency, long-Term cardiac expression of foreign genes in living mouse embryos and neonates
    • Christensen G, Minamisawa S, Gruber PJ, Wang Y, Chien KR. Highefficiency, long-Term cardiac expression of foreign genes in living mouse embryos and neonates. Circulation. 2000;101:178-184
    • (2000) Circulation , vol.101 , pp. 178-184
    • Christensen, G.1    Minamisawa, S.2    Gruber, P.J.3    Wang, Y.4    Chien, K.R.5
  • 37
    • 84866780434 scopus 로고    scopus 로고
    • Chapter six-Adenovirus-based immunotherapy of cancer: Promises to keep
    • De Gruijl TD, Van De Ven R. Chapter six-Adenovirus-based immunotherapy of cancer: Promises to keep. Adv Cancer Res. 2012;115:147-220
    • (2012) Adv Cancer Res , vol.115 , pp. 147-220
    • De Gruijl, T.D.1    Van De Ven, R.2
  • 38
    • 12844285608 scopus 로고    scopus 로고
    • Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer
    • Kikuchi K, McDonald AD, Sasano T, Donahue JK. Targeted modification of atrial electrophysiology by homogeneous transmural atrial gene transfer. Circulation. 2005;111:264-270
    • (2005) Circulation , vol.111 , pp. 264-270
    • Kikuchi, K.1    McDonald, A.D.2    Sasano, T.3    Donahue, J.K.4
  • 40
    • 84872867297 scopus 로고    scopus 로고
    • Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate
    • Gao Z, Rasmussen TP, Li Y, et al. Genetic inhibition of Na+-Ca2+ exchanger current disables fight or flight sinoatrial node activity without affecting resting heart rate. Circ Res. 2013;112:309-317
    • (2013) Circ Res , vol.112 , pp. 309-317
    • Gao, Z.1    Rasmussen, T.P.2    Li, Y.3
  • 44
    • 44349170706 scopus 로고    scopus 로고
    • Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
    • Zincarelli C, Soltys S, Rengo G, Rabinowitz JE. Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol Ther. 2008;16:1073-1080
    • (2008) Mol Ther , vol.16 , pp. 1073-1080
    • Zincarelli, C.1    Soltys, S.2    Rengo, G.3    Rabinowitz, J.E.4
  • 45
    • 33745143956 scopus 로고    scopus 로고
    • Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8
    • Inagaki K, Fuess S, Storm TA, Gibson GA, Mctiernan CF, Kay MA, Nakai H. Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8. Mol Ther. 2006;14:45-53
    • (2006) Mol Ther , vol.14 , pp. 45-53
    • Inagaki, K.1    Fuess, S.2    Storm, T.A.3    Gibson, G.A.4    Mctiernan, C.F.5    Kay, M.A.6    Nakai, H.7
  • 47
    • 79953677173 scopus 로고    scopus 로고
    • The next step in gene delivery: Molecular engineering of adeno-Associated virus serotypes
    • Wang J, Faust SM, Rabinowitz JE. The next step in gene delivery: Molecular engineering of adeno-Associated virus serotypes. J Mol Cell Cardiol. 2011;50:793-802
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 793-802
    • Wang, J.1    Faust, S.M.2    Rabinowitz, J.E.3
  • 49
    • 79951510234 scopus 로고    scopus 로고
    • Microrna122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors
    • Geisler A, Jungmann A, Kurreck J, Poller W, Katus HA, Vetter R, Fechner H, Müller OJ. microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors. Gene Ther. 2011;18:199-209
    • (2011) Gene Ther , vol.18 , pp. 199-209
    • Geisler, A.1    Jungmann, A.2    Kurreck, J.3    Poller, W.4    Katus, H.A.5    Vetter, R.6    Fechner, H.7    Müller, O.J.8
  • 51
    • 79960696509 scopus 로고    scopus 로고
    • Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model
    • 3:92ra64
    • Pleger ST, Shan C, Ksienzyk J, et al. Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model. Sci Transl Med. 2011;3:92ra64
    • (2011) Sci Transl Med
    • Pleger, S.T.1    Shan, C.2    Ksienzyk, J.3
  • 52
    • 45749138773 scopus 로고    scopus 로고
    • Recombinant adeno-Associated virus transduction and integration
    • Schultz BR, Chamberlain JS. Recombinant adeno-Associated virus transduction and integration. Mol Ther. 2008;16:1189-1199
    • (2008) Mol Ther , vol.16 , pp. 1189-1199
    • Schultz, B.R.1    Chamberlain, J.S.2
  • 55
    • 35848961457 scopus 로고    scopus 로고
    • Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration
    • Bostick B, Ghosh A, Yue Y, Long C, Duan D. Systemic AAV-9 transduction in mice is influenced by animal age but not by the route of administration. Gene Ther. 2007;14:1605-1609
    • (2007) Gene Ther , vol.14 , pp. 1605-1609
    • Bostick, B.1    Ghosh, A.2    Yue, Y.3    Long, C.4    Duan, D.5
  • 56
    • 3242706582 scopus 로고    scopus 로고
    • Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins
    • Nagai T, Yamada S, Tominaga T, Ichikawa M, Miyawaki A. Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins. Proc Natl Acad Sci U S A. 2004;101:10554-10559
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , pp. 10554-10559
    • Nagai, T.1    Yamada, S.2    Tominaga, T.3    Ichikawa, M.4    Miyawaki, A.5
  • 57
    • 5344232041 scopus 로고    scopus 로고
    • Fluorescent proteins as sensors for cellular functions
    • Griesbeck O. Fluorescent proteins as sensors for cellular functions. Curr Opin Neurobiol. 2004;14:636-641
    • (2004) Curr Opin Neurobiol , vol.14 , pp. 636-641
    • Griesbeck, O.1
  • 58
    • 56249108340 scopus 로고    scopus 로고
    • Measuring calcium dynamics in living cells with genetically encodable calcium indicators
    • McCombs JE, Palmer AE. Measuring calcium dynamics in living cells with genetically encodable calcium indicators. Methods. 2008;46:152-159
    • (2008) Methods , vol.46 , pp. 152-159
    • McCombs, J.E.1    Palmer, A.E.2
  • 59
    • 44849120336 scopus 로고    scopus 로고
    • Genetically encoded calcium indicators
    • Mank M, Griesbeck O. Genetically encoded calcium indicators. Chem Rev. 2008;108:1550-1564
    • (2008) Chem Rev , vol.108 , pp. 1550-1564
    • Mank, M.1    Griesbeck, O.2
  • 61
    • 84859130091 scopus 로고    scopus 로고
    • High-resolution imaging of Ca2+, redox status, ROS and pH using GFP biosensors
    • Choi WG, Swanson SJ, Gilroy S. High-resolution imaging of Ca2+, redox status, ROS and pH using GFP biosensors. Plant J. 2012;70:118-128
    • (2012) Plant J. , vol.70 , pp. 118-128
    • Choi, W.G.1    Swanson, S.J.2    Gilroy, S.3
  • 62
    • 84878246875 scopus 로고    scopus 로고
    • Genetically encoded Ca(2+) indicators: Properties and evaluation
    • Pérez Koldenkova V, Nagai T. Genetically encoded Ca(2+) indicators: Properties and evaluation. Biochim Biophys Acta. 2013;1833:1787-1797
    • (2013) Biochim Biophys Acta. , vol.1833 , pp. 1787-1797
    • Pérez Koldenkova, V.1    Nagai, T.2
  • 64
    • 33646145526 scopus 로고    scopus 로고
    • A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change
    • Mank M, Reiff DF, Heim N, Friedrich MW, Borst A, Griesbeck O. A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change. Biophys J. 2006;90:1790-1796
    • (2006) Biophys J. , vol.90 , pp. 1790-1796
    • Mank, M.1    Reiff, D.F.2    Heim, N.3    Friedrich, M.W.4    Borst, A.5    Griesbeck, O.6
  • 66
    • 0036052528 scopus 로고    scopus 로고
    • Circular permutation of the green fluorescent protein
    • Topell S, Glockshuber R. Circular permutation of the green fluorescent protein. Methods Mol Biol. 2002;183:31-48
    • (2002) Methods Mol Biol , vol.183 , pp. 31-48
    • Topell, S.1    Glockshuber, R.2
  • 67
    • 0027980367 scopus 로고
    • Intrinsic cytosolic calcium buffering properties of single rat cardiac myocytes
    • Berlin JR, Bassani JW, Bers DM. Intrinsic cytosolic calcium buffering properties of single rat cardiac myocytes. Biophys J. 1994;67:1775-1787
    • (1994) Biophys J. , vol.67 , pp. 1775-1787
    • Berlin, J.R.1    Bassani, J.W.2    Bers, D.M.3
  • 68
    • 0033626361 scopus 로고    scopus 로고
    • A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals
    • Thomas D, Tovey SC, Collins TJ, Bootman MD, Berridge MJ, Lipp P. A comparison of fluorescent Ca2+ indicator properties and their use in measuring elementary and global Ca2+ signals. Cell Calcium. 2000;28:213-223
    • (2000) Cell Calcium , vol.28 , pp. 213-223
    • Thomas, D.1    Tovey, S.C.2    Collins, T.J.3    Bootman, M.D.4    Berridge, M.J.5    Lipp, P.6
  • 69
    • 0021895138 scopus 로고
    • A new generation of Ca2+ indicators with greatly improved fluorescence properties
    • Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem. 1985;260:3440-3450
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 70
    • 0026031694 scopus 로고
    • Nanosecond fluorescence microscopy emission kinetics of fura-2 in single cells
    • Keating SM, Wensel TG. Nanosecond fluorescence microscopy. Emission kinetics of fura-2 in single cells. Biophys J. 1991;59:186-202
    • (1991) Biophys J. , vol.59 , pp. 186-202
    • Keating, S.M.1    Wensel, T.G.2
  • 71
  • 72
    • 0031663369 scopus 로고    scopus 로고
    • The green fluorescent protein
    • Tsien RY. The green fluorescent protein. Annu Rev Biochem. 1998;67:509-544
    • (1998) Annu Rev Biochem , vol.67 , pp. 509-544
    • Tsien, R.Y.1
  • 73
    • 3843051493 scopus 로고    scopus 로고
    • Functional topology of the mossy fibregranule cell-Purkinje cell system revealed by imaging of intrinsic fluorescence in mouse cerebellum
    • Coutinho V, Mutoh H, Knöpfel T. Functional topology of the mossy fibregranule cell-Purkinje cell system revealed by imaging of intrinsic fluorescence in mouse cerebellum. Eur J Neurosci. 2004;20:740-748
    • (2004) Eur J Neurosci , vol.20 , pp. 740-748
    • Coutinho, V.1    Mutoh, H.2    Knöpfel, T.3
  • 74
    • 33947187417 scopus 로고    scopus 로고
    • In vivo calcium imaging from genetically specified target cells in mouse cerebellum
    • Díez-García J, Akemann W, Knöpfel T. In vivo calcium imaging from genetically specified target cells in mouse cerebellum. Neuroimage. 2007;34:859-869
    • (2007) Neuroimage , vol.34 , pp. 859-869
    • Díez-García, J.1    Akemann, W.2    Knöpfel, T.3
  • 78
    • 0036924067 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer-based stoichiometry in living cells
    • Hoppe A, Christensen K, Swanson JA. Fluorescence resonance energy transfer-based stoichiometry in living cells. Biophys J. 2002;83:3652-3664
    • (2002) Biophys J. , vol.83 , pp. 3652-3664
    • Hoppe, A.1    Christensen, K.2    Swanson, J.A.3
  • 79
    • 84900867586 scopus 로고    scopus 로고
    • Investigating calcium signaling by confocal and multiphoton microscopy
    • doi: 10.1101/pdb. top066084 In press
    • Kaestner L, Lipp P. Investigating calcium signaling by confocal and multiphoton microscopy. Cold Spring Harb Protoc. 2014. doi: 10.1101/pdb. top066084. In press
    • (2014) Cold Spring Harb Protoc
    • Kaestner, L.1    Lipp, P.2
  • 80
    • 0031956092 scopus 로고    scopus 로고
    • Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy
    • Gordon GW, Berry G, Liang XH, Levine B, Herman B. Quantitative fluorescence resonance energy transfer measurements using fluorescence microscopy. Biophys J. 1998;74:2702-2713
    • (1998) Biophys J. , vol.74 , pp. 2702-2713
    • Gordon, G.W.1    Berry, G.2    Liang, X.H.3    Levine, B.4    Herman, B.5
  • 81
    • 0034810232 scopus 로고    scopus 로고
    • Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes
    • Xia Z, Liu Y. Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes. Biophys J. 2001;81:2395-2402
    • (2001) Biophys J. , vol.81 , pp. 2395-2402
    • Xia, Z.1    Liu, Y.2
  • 82
    • 0038101519 scopus 로고    scopus 로고
    • FRET or no FRET: A quantitative comparison
    • Berney C, Danuser G. FRET or no FRET: A quantitative comparison. Biophys J. 2003;84:3992-4010
    • (2003) Biophys J. , vol.84 , pp. 3992-4010
    • Berney, C.1    Danuser, G.2
  • 84
    • 84865068419 scopus 로고    scopus 로고
    • Screening action potentials: The power of light
    • Kaestner L, Lipp P. Screening action potentials: The power of light. Front Pharmacol. 2011;2:1-5
    • (2011) Front Pharmacol , vol.2 , pp. 1-5
    • Kaestner, L.1    Lipp, P.2
  • 85
    • 84858900673 scopus 로고    scopus 로고
    • I love my glow bunny
    • 904
    • Dickey C. I love my glow bunny. Wired. 2001;9.04:1-6
    • (2001) Wired , pp. 1-6
    • Dickey, C.1
  • 86
    • 26944499780 scopus 로고    scopus 로고
    • Innovations in the imaging of brain functions using fluorescent proteins
    • Miyawaki A. Innovations in the imaging of brain functions using fluorescent proteins. Neuron. 2005;48:189-199
    • (2005) Neuron , vol.48 , pp. 189-199
    • Miyawaki, A.1
  • 89
    • 0029864283 scopus 로고    scopus 로고
    • Photolysis of caged compounds characterized by ratiometric confocal microscopy: A new approach to homogeneously control and measure the calcium concentration in cardiac myocytes
    • Lipp P, Lüscher C, Niggli E. Photolysis of caged compounds characterized by ratiometric confocal microscopy: A new approach to homogeneously control and measure the calcium concentration in cardiac myocytes. Cell Calcium. 1996;19:255-266
    • (1996) Cell Calcium , vol.19 , pp. 255-266
    • Lipp, P.1    Lüscher, C.2    Niggli, E.3
  • 90
    • 0022838222 scopus 로고
    • Calcium-calmodulin interaction and cellular function
    • Cox JA. Calcium-calmodulin interaction and cellular function. J Cardiovasc Pharmacol. 1986;8(suppl 8):S48-S51
    • (1986) J Cardiovasc Pharmacol , vol.8 , Issue.SUPPL8
    • Cox, J.A.1
  • 92
    • 34547952060 scopus 로고    scopus 로고
    • Troponin C-based biosensors: A new family of genetically encoded indicators for in vivo calcium imaging in the nervous system
    • Garaschuk O, Griesbeck O, Konnerth A. Troponin C-based biosensors: A new family of genetically encoded indicators for in vivo calcium imaging in the nervous system. Cell Calcium. 2007;42:351-361
    • (2007) Cell Calcium , vol.42 , pp. 351-361
    • Garaschuk, O.1    Griesbeck, O.2    Konnerth, A.3
  • 93
    • 10644234677 scopus 로고    scopus 로고
    • Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
    • Palmer AE, Jin C, Reed JC, Tsien RY. Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci U S A. 2004;101:17404-17409
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , pp. 17404-17409
    • Palmer, A.E.1    Jin, C.2    Reed, J.C.3    Tsien, R.Y.4
  • 95
    • 1842790629 scopus 로고    scopus 로고
    • Genetically encoded indicators of cellular calcium dynamics based on troponin C and green fluorescent protein
    • Heim N, Griesbeck O. Genetically encoded indicators of cellular calcium dynamics based on troponin C and green fluorescent protein. J Biol Chem. 2004;279:14280-14286
    • (2004) J Biol Chem , vol.279 , pp. 14280-14286
    • Heim, N.1    Griesbeck, O.2
  • 96
    • 84860290586 scopus 로고    scopus 로고
    • Nanodomain Ca?+ of Ca?+ channels detected by a tethered genetically encoded Ca?+ sensor
    • Tay LH, Dick IE, Yang W, Mank M, Griesbeck O, Yue DT. Nanodomain Ca?+ of Ca?+ channels detected by a tethered genetically encoded Ca?+ sensor. Nat Commun. 2012;3:778
    • (2012) Nat Commun , vol.3 , pp. 778
    • Tay, L.H.1    Dick, I.E.2    Yang, W.3    Mank, M.4    Griesbeck, O.5    Yue, D.T.6
  • 99
    • 4043090758 scopus 로고    scopus 로고
    • Optical sectioning deep inside live embryos by selective plane illumination microscopy
    • Huisken J, Swoger J, Del Bene F, Wittbrodt J, Stelzer EH. Optical sectioning deep inside live embryos by selective plane illumination microscopy. Science. 2004;305:1007-1009
    • (2004) Science , vol.305 , pp. 1007-1009
    • Huisken, J.1    Swoger, J.2    Del Bene, F.3    Wittbrodt, J.4    Stelzer, E.H.5
  • 101
    • 33749347260 scopus 로고    scopus 로고
    • Reduced cardiac L-Type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation
    • Weissgerber P, Held B, Bloch W, Kaestner L, Chien KR, Fleischmann BK, Lipp P, Flockerzi V, Freichel M. Reduced cardiac L-Type Ca2+ current in Ca(V)beta2-/- embryos impairs cardiac development and contraction with secondary defects in vascular maturation. Circ Res. 2006;99:749-757
    • (2006) Circ Res , vol.99 , pp. 749-757
    • Weissgerber, P.1    Held, B.2    Bloch, W.3    Kaestner, L.4    Chien, K.R.5    Fleischmann, B.K.6    Lipp, P.7    Flockerzi, V.8    Freichel, M.9
  • 103
    • 36949035990 scopus 로고    scopus 로고
    • Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia
    • Roell W, Lewalter T, Sasse P, et al. Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia. Nature. 2007;450:819-824
    • (2007) Nature , vol.450 , pp. 819-824
    • Roell, W.1    Lewalter, T.2    Sasse, P.3
  • 104
    • 84866150446 scopus 로고    scopus 로고
    • Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
    • Shiba Y, Fernandes S, Zhu WZ, et al. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature. 2012;489:322-325
    • (2012) Nature , vol.489 , pp. 322-325
    • Shiba, Y.1    Fernandes, S.2    Zhu, W.Z.3
  • 106
    • 0034124270 scopus 로고    scopus 로고
    • Inositol 1 4,5-Trisphosphate directs Ca(2+) flow between mitochondria and the Endoplasmic/Sarcoplasmic reticulum: A role in regulating cardiac autonomic Ca(2+) spiking
    • Jaconi M, Bony C, Richards SM, Terzic A, Arnaudeau S, Vassort G, Pucéat M. Inositol 1,4,5-Trisphosphate directs Ca(2+) flow between mitochondria and the Endoplasmic/Sarcoplasmic reticulum: A role in regulating cardiac autonomic Ca(2+) spiking. Mol Biol Cell. 2000;11:1845-1858
    • (2000) Mol Biol Cell , vol.11 , pp. 1845-1858
    • Jaconi, M.1    Bony, C.2    Richards, S.M.3    Terzic, A.4    Arnaudeau, S.5    Vassort, G.6    Pucéat, M.7
  • 108
    • 0038575304 scopus 로고    scopus 로고
    • Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells
    • Bkaily G, Choufani S, Sader S, Jacques D, d'Orléans-Juste P, Nader M, Kurban G, Kamal M. Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells. Can J Physiol Pharmacol. 2003;81:654-662
    • (2003) Can J Physiol Pharmacol , vol.81 , pp. 654-662
    • Bkaily, G.1    Choufani, S.2    Sader, S.3    Jacques, D.4    D'Orléans-Juste, P.5    Nader, M.6    Kurban, G.7    Kamal, M.8
  • 110
    • 33748786501 scopus 로고    scopus 로고
    • ATP regulation in adult rat cardiomyocytes: Time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins
    • Bell CJ, Bright NA, Rutter GA, Griffiths EJ. ATP regulation in adult rat cardiomyocytes: Time-resolved decoding of rapid mitochondrial calcium spiking imaged with targeted photoproteins. J Biol Chem. 2006;281:28058-28067
    • (2006) J Biol Chem , vol.281 , pp. 28058-28067
    • Bell, C.J.1    Bright, N.A.2    Rutter, G.A.3    Griffiths, E.J.4
  • 113
    • 58649095123 scopus 로고    scopus 로고
    • Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose
    • Hu Y, Suarez J, Fricovsky E, Wang H, Scott BT, Trauger SA, Han W, Hu Y, Oyeleye MO, Dillmann WH. Increased enzymatic O-GlcNAcylation of mitochondrial proteins impairs mitochondrial function in cardiac myocytes exposed to high glucose. J Biol Chem. 2009;284:547-555
    • (2009) J Biol Chem , vol.284 , pp. 547-555
    • Hu, Y.1    Suarez, J.2    Fricovsky, E.3    Wang, H.4    Scott, B.T.5    Trauger, S.A.6    Han, W.7    Hu, Y.8    Oyeleye, M.O.9    Dillmann, W.H.10
  • 114
    • 67349265604 scopus 로고    scopus 로고
    • Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria
    • Kettlewell S, Cabrero P, Nicklin SA, Dow JA, Davies S, Smith GL. Changes of intra-mitochondrial Ca2+ in adult ventricular cardiomyocytes examined using a novel fluorescent Ca2+ indicator targeted to mitochondria. J Mol Cell Cardiol. 2009;46:891-901
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 891-901
    • Kettlewell, S.1    Cabrero, P.2    Nicklin, S.A.3    Dow, J.A.4    Davies, S.5    Smith, G.L.6
  • 115
    • 84873410873 scopus 로고    scopus 로고
    • Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release
    • Lu X, Ginsburg KS, Kettlewell S, Bossuyt J, Smith GL, Bers DM. Measuring local gradients of intramitochondrial [Ca(2+)] in cardiac myocytes during sarcoplasmic reticulum Ca(2+) release. Circ Res. 2013;112:424-431
    • (2013) Circ Res. , vol.112 , pp. 424-431
    • Lu, X.1    Ginsburg, K.S.2    Kettlewell, S.3    Bossuyt, J.4    Smith, G.L.5    Bers, D.M.6
  • 116
    • 0025060957 scopus 로고
    • Spatial heterogeneity of intracellular Ca2+ concentration in nonbeating guinea pig ventricular myocytes
    • Williford DJ, Sharma VK, Korth M, Sheu SS. Spatial heterogeneity of intracellular Ca2+ concentration in nonbeating guinea pig ventricular myocytes. Circ Res. 1990;66:241-248
    • (1990) Circ Res , vol.66 , pp. 241-248
    • Williford, D.J.1    Sharma, V.K.2    Korth, M.3    Sheu, S.S.4
  • 117
    • 84155189038 scopus 로고    scopus 로고
    • Measuring mitochondrial function in intact cardiac myocytes
    • Dedkova EN, Blatter LA. Measuring mitochondrial function in intact cardiac myocytes. J Mol Cell Cardiol. 2012;52:48-61
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 48-61
    • Dedkova, E.N.1    Blatter, L.A.2
  • 120
    • 84900847311 scopus 로고    scopus 로고
    • Concepts for optical high content screens of excitable primary isolated cells for molecular imaging
    • Kaestner L, Ruppenthal S, Schwarz S, Scholz A, Lipp P. Concepts for optical high content screens of excitable primary isolated cells for molecular imaging. Prog Biophys Mol Biol. 2009;10:737008-1-737008-8
    • (2009) Prog Biophys Mol Biol , vol.10 , pp. 7370081-7370088
    • Kaestner, L.1    Ruppenthal, S.2    Schwarz, S.3    Scholz, A.4    Lipp, P.5
  • 121
    • 77649274601 scopus 로고    scopus 로고
    • A system for optical high resolution screening of electrical excitable cells
    • Müller O, Tian Q, Zantl R, Kahl V, Lipp P, Kaestner L. A system for optical high resolution screening of electrical excitable cells. Cell Calcium. 2010;47:224-233
    • (2010) Cell Calcium , vol.47 , pp. 224-233
    • Müller, O.1    Tian, Q.2    Zantl, R.3    Kahl, V.4    Lipp, P.5    Kaestner, L.6
  • 123
    • 33845638694 scopus 로고    scopus 로고
    • Diversity of Ca2+ signaling in developing cardiac cells
    • Janowski E, Cleemann L, Sasse P, Morad M. Diversity of Ca2+ signaling in developing cardiac cells. Ann N Y Acad Sci. 2006;1080:154-164
    • (2006) Ann N Y Acad Sci , vol.1080 , pp. 154-164
    • Janowski, E.1    Cleemann, L.2    Sasse, P.3    Morad, M.4
  • 126
    • 84883651986 scopus 로고    scopus 로고
    • Circular permutated red fluorescent proteins and calcium ion indicators based on mCherry
    • Carlson HJ, Campbell RE. Circular permutated red fluorescent proteins and calcium ion indicators based on mCherry. Protein Eng Des Sel. 2013;26:763-772
    • (2013) Protein Eng Des Sel , vol.26 , pp. 763-772
    • Carlson, H.J.1    Campbell, R.E.2
  • 128
    • 85027921633 scopus 로고    scopus 로고
    • Noise-free visualization of microscopic calcium signaling by pixel-wise fitting
    • Tian Q, Kaestner L, Lipp P. Noise-free visualization of microscopic calcium signaling by pixel-wise fitting. Circ Res. 2012;111:17-27
    • (2012) Circ Res , vol.111 , pp. 17-27
    • Tian, Q.1    Kaestner, L.2    Lipp, P.3
  • 130
    • 48449091054 scopus 로고    scopus 로고
    • Improving membrane voltage measurements using FRET with new fluorescent proteins
    • Tsutsui H, Karasawa S, Okamura Y, Miyawaki A. Improving membrane voltage measurements using FRET with new fluorescent proteins. Nat Methods. 2008;5:683-685
    • (2008) Nat Methods , vol.5 , pp. 683-685
    • Tsutsui, H.1    Karasawa, S.2    Okamura, Y.3    Miyawaki, A.4
  • 131
    • 0037780971 scopus 로고    scopus 로고
    • A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
    • Violin JD, Zhang J, Tsien RY, Newton AC. A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C. J Cell Biol. 2003;161:899-909
    • (2003) J Cell Biol , vol.161 , pp. 899-909
    • Violin, J.D.1    Zhang, J.2    Tsien, R.Y.3    Newton, A.C.4
  • 132
  • 135
    • 0026659512 scopus 로고
    • Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin
    • Rizzuto R, Simpson AW, Brini M, Pozzan T. Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin. Nature. 1992;358:325-327
    • (1992) Nature , vol.358 , pp. 325-327
    • Rizzuto, R.1    Simpson, A.W.2    Brini, M.3    Pozzan, T.4
  • 136
    • 0024309191 scopus 로고
    • Use of calcium-regulated photoproteins as intracellular Ca2+ indicators
    • Blinks JR. Use of calcium-regulated photoproteins as intracellular Ca2+ indicators. Methods Enzymol. 1989;172:164-203
    • (1989) Methods Enzymol , vol.172 , pp. 164-203
    • Blinks, J.R.1
  • 138
    • 70350641398 scopus 로고    scopus 로고
    • A nuclear-Targeted cameleon demonstrates intranuclear Ca2+ spiking in Medicago truncatula root hairs in response to rhizobial nodulation factors
    • Sieberer BJ, Chabaud M, Timmers AC, Monin A, Fournier J, Barker DG. A nuclear-Targeted cameleon demonstrates intranuclear Ca2+ spiking in Medicago truncatula root hairs in response to rhizobial nodulation factors. Plant Physiol. 2009;151:1197-1206
    • (2009) Plant Physiol , vol.151 , pp. 1197-1206
    • Sieberer, B.J.1    Chabaud, M.2    Timmers, A.C.3    Monin, A.4    Fournier, J.5    Barker, D.G.6
  • 139
    • 37749003256 scopus 로고    scopus 로고
    • Tracking transmitter-gated P2X cation channel activation in vitro and in vivo
    • Richler E, Chaumont S, Shigetomi E, Sagasti A, Khakh BS. Tracking transmitter-gated P2X cation channel activation in vitro and in vivo. Nat Methods. 2008;5:87-93
    • (2008) Nat Methods , vol.5 , pp. 87-93
    • Richler, E.1    Chaumont, S.2    Shigetomi, E.3    Sagasti, A.4    Khakh, B.S.5
  • 140
    • 80052746580 scopus 로고    scopus 로고
    • Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation- contraction (E-C) coupling
    • Yi J, Ma C, Li Y, Weisleder N, Ríos E, Ma J, Zhou J. Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation- contraction (E-C) coupling. J Biol Chem. 2011;286:32436-32443
    • (2011) J Biol Chem , vol.286 , pp. 32436-32443
    • Yi, J.1    Ma, C.2    Li, Y.3    Weisleder, N.4    Ríos, E.5    Ma, J.6    Zhou, J.7
  • 141
    • 49049094473 scopus 로고    scopus 로고
    • Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activity and calcium in vivo and in vitro
    • Hendel T, Mank M, Schnell B, Griesbeck O, Borst A, Reiff DF. Fluorescence changes of genetic calcium indicators and OGB-1 correlated with neural activity and calcium in vivo and in vitro. J Neurosci. 2008;28:7399-7411
    • (2008) J Neurosci , vol.28 , pp. 7399-7411
    • Hendel, T.1    Mank, M.2    Schnell, B.3    Griesbeck, O.4    Borst, A.5    Reiff, D.F.6
  • 142
    • 77952710840 scopus 로고    scopus 로고
    • Unique characteristics of Ca2+ homeostasis of the trans-Golgi compartment
    • Lissandron V, Podini P, Pizzo P, Pozzan T. Unique characteristics of Ca2+ homeostasis of the trans-Golgi compartment. Proc Natl Acad Sci U S A. 2010;107:9198-9203
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , pp. 9198-9203
    • Lissandron, V.1    Podini, P.2    Pizzo, P.3    Pozzan, T.4
  • 144
    • 33745841505 scopus 로고    scopus 로고
    • Differential gel electrophoresis and transgenic mitochondrial calcium reporters demonstrate spatiotemporal filtering in calcium control of mitochondria
    • Terhzaz S, Southall TD, Lilley KS, Kean L, Allan AK, Davies SA, Dow JA. Differential gel electrophoresis and transgenic mitochondrial calcium reporters demonstrate spatiotemporal filtering in calcium control of mitochondria. J Biol Chem. 2006;281:18849-18858
    • (2006) J Biol Chem , vol.281 , pp. 18849-18858
    • Terhzaz, S.1    Southall, T.D.2    Lilley, K.S.3    Kean, L.4    Allan, A.K.5    Davies, S.A.6    Dow, J.A.7
  • 145
    • 46349085255 scopus 로고    scopus 로고
    • Characterization and subcellular targeting of GCaMP-Type genetically-encoded calcium indicators
    • Mao T, O'Connor DH, Scheuss V, Nakai J, Svoboda K. Characterization and subcellular targeting of GCaMP-Type genetically-encoded calcium indicators. PLoS One. 2008;3:e1796
    • (2008) PLoS One , vol.3
    • Mao, T.1    O'Connor, D.H.2    Scheuss, V.3    Nakai, J.4    Svoboda, K.5
  • 146
    • 72449177003 scopus 로고    scopus 로고
    • Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase
    • Willoughby D, Wachten S, Masada N, Cooper DM. Direct demonstration of discrete Ca2+ microdomains associated with different isoforms of adenylyl cyclase. J Cell Sci. 2010;123:107-117
    • (2010) J Cell Sci , vol.123 , pp. 107-117
    • Willoughby, D.1    Wachten, S.2    Masada, N.3    Cooper, D.M.4
  • 147
    • 77949884841 scopus 로고    scopus 로고
    • ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel
    • Barro-Soria R, Aldehni F, Alma'a J, Witzgall R, Schreiber R, Kunzelmann K. ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel. Pflugers Arch. 2010;459:485-497
    • (2010) Pflugers Arch , vol.459 , pp. 485-497
    • Barro-Soria, R.1    Aldehni, F.2    Alma'a, J.3    Witzgall, R.4    Schreiber, R.5    Kunzelmann, K.6
  • 148
  • 149
    • 84862198234 scopus 로고    scopus 로고
    • Direct monitoring of mitochondrial calcium levels in cultured cardiac myocytes using a novel fluorescent indicator protein, GCaMP2-mt
    • Iguchi M, Kato M, Nakai J, Takeda T, Matsumoto-Ida M, Kita T, Kimura T, Akao M. Direct monitoring of mitochondrial calcium levels in cultured cardiac myocytes using a novel fluorescent indicator protein, GCaMP2-mt. Int J Cardiol. 2012;158:225-234
    • (2012) Int J Cardiol , vol.158 , pp. 225-234
    • Iguchi, M.1    Kato, M.2    Nakai, J.3    Takeda, T.4    Matsumoto-Ida, M.5    Kita, T.6    Kimura, T.7    Akao, M.8
  • 150
    • 77952884848 scopus 로고    scopus 로고
    • A genetically targeted optical sensor to monitor calcium signals in astrocyte processes
    • Shigetomi E, Kracun S, Sofroniew MV, Khakh BS. A genetically targeted optical sensor to monitor calcium signals in astrocyte processes. Nat Neurosci. 2010;13:759-766
    • (2010) Nat Neurosci , vol.13 , pp. 759-766
    • Shigetomi, E.1    Kracun, S.2    Sofroniew, M.V.3    Khakh, B.S.4
  • 151
    • 57049110387 scopus 로고    scopus 로고
    • Reporting neural activity with genetically encoded calcium indicators
    • Hires SA, Tian L, Looger LL. Reporting neural activity with genetically encoded calcium indicators. Brain Cell Biol. 2008;36:69-86
    • (2008) Brain Cell Biol , vol.36 , pp. 69-86
    • Hires, S.A.1    Tian, L.2    Looger, L.L.3
  • 153
    • 79960361861 scopus 로고    scopus 로고
    • Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters
    • Shigetomi E, Kracun S, Khakh BS. Monitoring astrocyte calcium microdomains with improved membrane targeted GCaMP reporters. Neuron Glia Biol. 2010;6:183-191
    • (2010) Neuron Glia Biol , vol.6 , pp. 183-191
    • Shigetomi, E.1    Kracun, S.2    Khakh, B.S.3
  • 155
    • 84862842299 scopus 로고    scopus 로고
    • Gaq and Ga11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes
    • Pahlavan S, Oberhofer M, Sauer B, Ruppenthal S, Tian Q, Scholz A, Kaestner L, Lipp P. Gaq and Ga11 contribute to the maintenance of cellular electrophysiology and Ca2+ handling in ventricular cardiomyocytes. Cardiovasc Res. 2012;95:48-58
    • (2012) Cardiovasc Res , vol.95 , pp. 48-58
    • Pahlavan, S.1    Oberhofer, M.2    Sauer, B.3    Ruppenthal, S.4    Tian, Q.5    Scholz, A.6    Kaestner, L.7    Lipp, P.8
  • 156
    • 17844366317 scopus 로고    scopus 로고
    • Protein kinase C delta and epsilon mediate positive inotropy in adult ventricular myocytes
    • Kang M, Walker JW. Protein kinase C delta and epsilon mediate positive inotropy in adult ventricular myocytes. J Mol Cell Cardiol. 2005;38:753-764
    • (2005) J Mol Cell Cardiol , vol.38 , pp. 753-764
    • Kang, M.1    Walker, J.W.2
  • 157
    • 0027467564 scopus 로고
    • Calcium transients and calcium release in rat fast-Twitch skeletal muscle fibres
    • Garcia J, Schneider MF. Calcium transients and calcium release in rat fast-Twitch skeletal muscle fibres. J Physiol. 1993;463:709-728
    • (1993) J Physiol , vol.463 , pp. 709-728
    • Garcia, J.1    Schneider, M.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.