메뉴 건너뛰기




Volumn 10, Issue , 2011, Pages 128-144

Drug resistance in Mycobacterium tuberculosis: Molecular mechanisms and laboratory susceptibility testing

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84900562607     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1159/000324630     Document Type: Chapter
Times cited : (4)

References (105)
  • 1
    • 84964134387 scopus 로고
    • Substance exhibiting activity against Gram-positive and Gram-negative bacteria
    • Schatz A, Bugie E, Waksman SA: Substance exhibiting activity against Gram-positive and Gram-negative bacteria. Proc Soc Exp Biol Med 1944;55:66-69.
    • (1944) Proc Soc Exp Biol Med , vol.55 , pp. 66-69
    • Schatz, A.1    Bugie, E.2    Waksman, S.A.3
  • 2
    • 0002162781 scopus 로고
    • Para-aminosalicylic acid in the treatment of tuberculosis
    • Lehman J: Para-aminosalicylic acid in the treatment of tuberculosis. Lancet 1946;250:15-16.
    • (1946) Lancet , vol.250 , pp. 15-16
    • Lehman, J.1
  • 3
    • 0000076527 scopus 로고
    • Relative numbers of resistant tubercule bacilli in sputa of patients before and during treatment with streptomycin
    • Pyle MM: Relative numbers of resistant tubercule bacilli in sputa of patients before and during treatment with streptomycin. Proc Mayo Clin 1947;22:465-473.
    • (1947) Proc Mayo Clin , vol.22 , pp. 465-473
    • Pyle, M.M.1
  • 4
    • 0001472399 scopus 로고
    • Treatment of pulmonary tuberculosis with streptomycin and paraamino salicylic acid
    • Medical Research Council: Treatment of pulmonary tuberculosis with streptomycin and paraamino salicylic acid. Br Med J 1950;ii:1073-1085.
    • (1950) Br Med J , vol.2 , pp. 1073-1085
  • 5
    • 84970843943 scopus 로고
    • Various combinations of isoniazid with streptomycin or with PAS in the treatment of pulmonary tuberculosis
    • Medical Research Council: Various combinations of isoniazid with streptomycin or with PAS in the treatment of pulmonary tuberculosis. Br Med J 1955;i:435-445.
    • (1955) Br Med J , vol.1 , pp. 435-445
  • 6
    • 76949116151 scopus 로고
    • Pyrazinamide (aldinamide) in the treatment of pulmonary tuberculosis
    • Yeager R, Monroe WE, Dessaus FI: Pyrazinamide (aldinamide) in the treatment of pulmonary tuberculosis. Am Rev Tuberc 1952;65:523-546.
    • (1952) Am Rev Tuberc , vol.65 , pp. 523-546
    • Yeager, R.1    Monroe, W.E.2    Dessaus, F.I.3
  • 8
    • 73049128716 scopus 로고
    • A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol)
    • Thomas JP, Baughn CO, Wilkinson RG, Shephard RG: A new synthetic compound with antituberculous activity in mice: ethambutol (dextro-2,2'-(ethylenediimino)-di-l-butanol). Am Rev Respir Dis 1961;83:891-893.
    • (1961) Am Rev Respir Dis , vol.83 , pp. 891-893
    • Thomas, J.P.1    Baughn, C.O.2    Wilkinson, R.G.3    Shephard, R.G.4
  • 9
    • 84890265975 scopus 로고
    • Controlled clinical trial of short-course (6 months) regimens of chemotherapy for treatment of pulmonary tuberculosis
    • British Medical Research Council: Controlled clinical trial of short-course (6 months) regimens of chemotherapy for treatment of pulmonary tuberculosis. Lancet 1972;i:1072-1085.
    • (1972) Lancet , vol.1 , pp. 1072-1085
  • 10
    • 0019955610 scopus 로고
    • A controlled trial of six month chemotherapy in pulmonary tuberculosis:second report results during the 24 months after the end of chemotherapy
    • British Thoracic Association: A controlled trial of six month chemotherapy in pulmonary tuberculosis:second report results during the 24 months after the end of chemotherapy. Am Rev Respir Dis 1982;126:460-462.
    • (1982) Am Rev Respir Dis , vol.126 , pp. 460-462
  • 11
    • 0022030585 scopus 로고
    • Mechanisms of the action of drugs in short-course chemotherapy
    • Mitchison DA: Mechanisms of the action of drugs in short-course chemotherapy. Bull Int Union Tuberc 1985;60:36-40.
    • (1985) Bull Int Union Tuberc , vol.60 , pp. 36-40
    • Mitchison, D.A.1
  • 12
    • 0032821532 scopus 로고    scopus 로고
    • Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications
    • Fox W, Ellard GA, Mitchison DA: Studies on the treatment of tuberculosis undertaken by the British Medical Research Council tuberculosis units, 1946-1986, with relevant subsequent publications. Int J Tuberc Lung Dis 1999;10(suppl 2):S231-S279.
    • (1999) Int J Tuberc Lung Dis , vol.10 , pp. S231-S279
    • Fox, W.1    Ellard, G.A.2    Mitchison, D.A.3
  • 13
    • 33947666691 scopus 로고    scopus 로고
    • Why is long-term therapy required to cure tuberculosis?
    • Connolly LE, Edelstein PH, Ramakrishnan L: Why is long-term therapy required to cure tuberculosis? PLoS Med 2007;4:e120.
    • (2007) PLoS Med , vol.4 , pp. e120
    • Connolly, L.E.1    Edelstein, P.H.2    Ramakrishnan, L.3
  • 14
    • 0014876878 scopus 로고
    • Probability distribution of drugresistant mutants in unselected populations of Mycobacterium tuberculosis
    • David HL: Probability distribution of drugresistant mutants in unselected populations of Mycobacterium tuberculosis. Appl Microbiol 1970;20:810-814.
    • (1970) Appl Microbiol , vol.20 , pp. 810-814
    • David, H.L.1
  • 15
    • 0032466234 scopus 로고    scopus 로고
    • Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update
    • Ramaswamy S, Musser JM: Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update. Tuberc Lung Dis 1998;79:3-29.
    • (1998) Tuberc Lung Dis , vol.79 , pp. 3-29
    • Ramaswamy, S.1    Musser, J.M.2
  • 16
    • 2542475123 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in Mycobacterium tuberculosis
    • Wade MM, Zhang Y: Mechanisms of drug resistance in Mycobacterium tuberculosis. Front Biosci 2004;9:975-994.
    • (2004) Front Biosci , vol.9 , pp. 975-994
    • Wade, M.M.1    Zhang, Y.2
  • 17
    • 84873118897 scopus 로고    scopus 로고
    • Mechanisms of drug resistance in Mycobacterium tuberculosis
    • Wax RG, Lewis K, Salyers AA, Taber H (eds), ed 2. Boca Raton, CRC Press-Taylor & Francis Group
    • Pym AS, Cole ST: Mechanisms of drug resistance in Mycobacterium tuberculosis; in Wax RG, Lewis K, Salyers AA, Taber H (eds): Bacterial Resistance to Antimicrobials, ed 2. Boca Raton, CRC Press-Taylor & Francis Group, 2008, pp 313-342.
    • (2008) Bacterial Resistance to Antimicrobials , pp. 313-342
    • Pym, A.S.1    Cole, S.T.2
  • 18
    • 33645916397 scopus 로고    scopus 로고
    • Mechanisms of mycobacterial drug resistance: implications for treatment and prevention strategies
    • Böttger EC: Mechanisms of mycobacterial drug resistance: implications for treatment and prevention strategies. Chemotherapy 2006;15:23-28.
    • (2006) Chemotherapy , vol.15 , pp. 23-28
    • Böttger, E.C.1
  • 19
    • 37549025845 scopus 로고    scopus 로고
    • Tuberculosis: drug resistance, fitness and strategies for global control
    • Böttger EC, Springer B: Tuberculosis: drug resistance, fitness and strategies for global control. Eur J Pediatr 2008;167:141-148.
    • (2008) Eur J Pediatr , vol.167 , pp. 141-148
    • Böttger, E.C.1    Springer, B.2
  • 20
    • 0028082028 scopus 로고
    • Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance
    • Meier A, Kirschner P, Bange FC, Vogel U, Böttger EC: Genetic alterations in streptomycin-resistant Mycobacterium tuberculosis: mapping of mutations conferring resistance. Antimicrob Agents Chemother 1994;38:228-233.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 228-233
    • Meier, A.1    Kirschner, P.2    Bange, F.C.3    Vogel, U.4    Böttger, E.C.5
  • 22
    • 77955362067 scopus 로고    scopus 로고
    • Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis
    • Shcherbakov D, Akbergenov R, Matt T, Sander P, Andersson DI, Böttger EC: Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis. Mol Microbiol 2010;77:830-840.
    • (2010) Mol Microbiol , vol.77 , pp. 830-840
    • Shcherbakov, D.1    Akbergenov, R.2    Matt, T.3    Sander, P.4    Andersson, D.I.5    Böttger, E.C.6
  • 24
    • 0002769662 scopus 로고
    • Antimicrobial agents and susceptibility tests: mycobacteria
    • Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds), Washington, American Society for Microbiology
    • Inderlied CB, Salfinger M: Antimicrobial agents and susceptibility tests: mycobacteria; in Murray PR, Baron EJ, Pfaller MA, Tenover FC, Yolken RH (eds): Manual of Clinical Microbiology. Washington, American Society for Microbiology, 1995, pp 1385-1404.
    • (1995) Manual of Clinical Microbiology , pp. 1385-1404
    • Inderlied, C.B.1    Salfinger, M.2
  • 25
  • 26
    • 0022638015 scopus 로고
    • Evaluation of streptomycin and ethambutol concentrations for susceptibility testing of Mycobacterium tuberculosis by radiometric and conventional procedures
    • Woodley CL: Evaluation of streptomycin and ethambutol concentrations for susceptibility testing of Mycobacterium tuberculosis by radiometric and conventional procedures. J Clin Microbiol 1986;23:385-386.
    • (1986) J Clin Microbiol , vol.23 , pp. 385-386
    • Woodley, C.L.1
  • 28
    • 0031151411 scopus 로고    scopus 로고
    • Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD supranational laboratory network: first round of proficiency testing
    • Laszló A, Rahman M, Raviglione M, Bustreo F, WHO/IUATLD Network of Supranational Reference Laboratories: Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD supranational laboratory network: first round of proficiency testing. Int J Tuberc Lung Dis 1997;1:231-238.
    • (1997) Int J Tuberc Lung Dis , vol.1 , pp. 231-238
    • Laszló, A.1    Rahman, M.2    Raviglione, M.3    Bustreo, F.4
  • 29
    • 0026705772 scopus 로고
    • The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis
    • Zhang Y, Heym B, Allen B, Young D, Cole S: The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis. Nature 1992;358:591-593.
    • (1992) Nature , vol.358 , pp. 591-593
    • Zhang, Y.1    Heym, B.2    Allen, B.3    Young, D.4    Cole, S.5
  • 31
    • 0028886398 scopus 로고
    • Characterization of the katG and inhA genes of isoniazid resistant clinical isolates of Mycobacterium tuberculosis
    • Rouse DA, Li Z, Bai GH, Morris SL: Characterization of the katG and inhA genes of isoniazid resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother 1995;39:2472-2477.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 2472-2477
    • Rouse, D.A.1    Li, Z.2    Bai, G.H.3    Morris, S.L.4
  • 32
    • 0030042509 scopus 로고    scopus 로고
    • Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and-susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance
    • Musser JM, Kapur V, Williams DL, Kreiswirth BN, van Soolingen D, van Embden, JD: Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and-susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance. J Infect Dis 1996;173:196-202.
    • (1996) J Infect Dis , vol.173 , pp. 196-202
    • Musser, J.M.1    Kapur, V.2    Williams, D.L.3    Kreiswirth, B.N.4    van Soolingen, D.5    van Embden, J.D.6
  • 33
    • 0031196349 scopus 로고    scopus 로고
    • Usefulness of Mycobacterium tuberculosis genomic mutations in the genes katG and inhA for the prediction of isoniazid resistance
    • Dobner P, Rusch-Gerdes S, Bretzel G, Feldmann K, Rifai M, Loscher T, Rinder H: Usefulness of Mycobacterium tuberculosis genomic mutations in the genes katG and inhA for the prediction of isoniazid resistance. Int J Tuberc Lung Dis 1997;1:365-369.
    • (1997) Int J Tuberc Lung Dis , vol.1 , pp. 365-369
    • Dobner, P.1    Rusch-Gerdes, S.2    Bretzel, G.3    Feldmann, K.4    Rifai, M.5    Loscher, T.6    Rinder, H.7
  • 34
    • 33845666699 scopus 로고    scopus 로고
    • Use of smear-positive samples to assess the PCR-based genotype MTBDR assay for rapid, direct detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampicin
    • Somoskovi A, Dormandy J, Mitsani D, Rivenburg J, Salfinger M: Use of smear-positive samples to assess the PCR-based genotype MTBDR assay for rapid, direct detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampicin. J Clin Microbiol 2006;44:4459-4463.
    • (2006) J Clin Microbiol , vol.44 , pp. 4459-4463
    • Somoskovi, A.1    Dormandy, J.2    Mitsani, D.3    Rivenburg, J.4    Salfinger, M.5
  • 35
    • 0031716180 scopus 로고    scopus 로고
    • A Ser315Thr substitution in KatG is predominant in genetically heterogeneous multidrug-resistant Mycobacterium tuberculosis isolates originating from the St Petersburg area in Russia
    • Marttila HJ, Soini H, Eerola E, Vyshnevskya E, Vyshnevskaya BI, Otten TF, Vasilyef AV, Viljanen MK: A Ser315Thr substitution in KatG is predominant in genetically heterogeneous multidrug-resistant Mycobacterium tuberculosis isolates originating from the St Petersburg area in Russia. Antimicrob Agents Chemother 1998;42:2443-2445.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 2443-2445
    • Marttila, H.J.1    Soini, H.2    Eerola, E.3    Vyshnevskya, E.4    Vyshnevskaya, B.I.5    Otten, T.F.6    Vasilyef, A.V.7    Viljanen, M.K.8
  • 37
    • 57349120030 scopus 로고    scopus 로고
    • Tuberculosis drug resistance in an area of low endemicity in 2004 to 2006: semiquantitative drug susceptibility testing and genotyping
    • Springer B, Calligaris-Maibach RC, Ritter C, Böttger EC: Tuberculosis drug resistance in an area of low endemicity in 2004 to 2006: semiquantitative drug susceptibility testing and genotyping. J Clin Microbiol 2008;46:4064-4067.
    • (2008) J Clin Microbiol , vol.46 , pp. 4064-4067
    • Springer, B.1    Calligaris-Maibach, R.C.2    Ritter, C.3    Böttger, E.C.4
  • 38
    • 66749172966 scopus 로고    scopus 로고
    • Quantitative drug susceptibility testing of Mycobacterium tuberculosis by use of MGIT 960 and EpiCenter instrumentation
    • Springer B, Lucke K, Calligaris-Maibach RC, Ritter C, Böttger EC: Quantitative drug susceptibility testing of Mycobacterium tuberculosis by use of MGIT 960 and EpiCenter instrumentation. J Clin Microbiol 2009;47:1773-1780.
    • (2009) J Clin Microbiol , vol.47 , pp. 1773-1780
    • Springer, B.1    Lucke, K.2    Calligaris-Maibach, R.C.3    Ritter, C.4    Böttger, E.C.5
  • 40
    • 69049098197 scopus 로고    scopus 로고
    • Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance
    • Bergval IL, Schuitema AR, Klatser PR, Anthony RM: Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance. J Antimicrob Chemother 2009;64:512-523.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 512-523
    • Bergval, I.L.1    Schuitema, A.R.2    Klatser, P.R.3    Anthony, R.M.4
  • 43
    • 33746871149 scopus 로고    scopus 로고
    • Resistance levels and rpoB gene mutations among in vitro-selected rifampicin-resistant Mycobacterium tuberculosis mutants
    • Huitric E, Werngren J, Juréen P, Hoffner S: Resistance levels and rpoB gene mutations among in vitro-selected rifampicin-resistant Mycobacterium tuberculosis mutants. Antimicrob Agents Chemother 2006;50:2860-2862.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2860-2862
    • Huitric, E.1    Werngren, J.2    Juréen, P.3    Hoffner, S.4
  • 44
    • 0024431530 scopus 로고
    • Inhibition of synthesis of arabinogalactane by ethambutol in Mycobacterium smegmatis
    • Takayama K, Kilburn JO: Inhibition of synthesis of arabinogalactane by ethambutol in Mycobacterium smegmatis. Antimicrob Agents Chemother 1989;33:1493-1499.
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 1493-1499
    • Takayama, K.1    Kilburn, J.O.2
  • 47
    • 62949172213 scopus 로고    scopus 로고
    • Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis
    • Starks AM, Gumusboga A, Plikaytis BB, Shinnick TM, Posey JE: Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2009;53:1061-1066.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 1061-1066
    • Starks, A.M.1    Gumusboga, A.2    Plikaytis, B.B.3    Shinnick, T.M.4    Posey, J.E.5
  • 48
    • 73849116052 scopus 로고    scopus 로고
    • Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis
    • Safi H, Fleischmann RD, Peterson SN, Jones MB, Jarrahi B, Alland D: Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2010;54:103-108.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 103-108
    • Safi, H.1    Fleischmann, R.D.2    Peterson, S.N.3    Jones, M.B.4    Jarrahi, B.5    Alland, D.6
  • 49
    • 71849102905 scopus 로고    scopus 로고
    • Tuberculosis ethambutol resistance: concordance between phenotypic and genotypic test results
    • Plinke C, Cox HS, Kalon S, Doshetov D, Rusch-Gerdes S, Niemann S: Tuberculosis ethambutol resistance: concordance between phenotypic and genotypic test results. Tuberculosis 2009;89:448-452.
    • (2009) Tuberculosis , vol.89 , pp. 448-452
    • Plinke, C.1    Cox, H.S.2    Kalon, S.3    Doshetov, D.4    Rusch-Gerdes, S.5    Niemann, S.6
  • 50
    • 0029954860 scopus 로고    scopus 로고
    • Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus
    • Scorpio A, Zhang Y: Mutations in pncA, a gene encoding pyrazinamidase/nicotinamidase, cause resistance to the antituberculous drug pyrazinamide in tubercle bacillus. Nat Med 1996;2:662-667.
    • (1996) Nat Med , vol.2 , pp. 662-667
    • Scorpio, A.1    Zhang, Y.2
  • 52
    • 0032876287 scopus 로고    scopus 로고
    • Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis
    • Mestdagh M, Fonteyne PA, Realini L, Rossau R, Jannes G, Mijs W, De Smet KA, Portaels F, van den Eeckhout E: Relationship between pyrazinamide resistance, loss of pyrazinamidase activity, and mutations in the pncA locus in multidrug-resistant clinical isolates of Mycobacterium tuberculosis. Antimicrob Agents Chemother 1999;43:2317-2319.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 2317-2319
    • Mestdagh, M.1    Fonteyne, P.A.2    Realini, L.3    Rossau, R.4    Jannes, G.5    Mijs, W.6    De Smet, K.A.7    Portaels, F.8    van den Eeckhout, E.9
  • 53
    • 0032799334 scopus 로고    scopus 로고
    • Characterization of new mutations in pyrazinamide resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase pncA
    • Lemaitre N, Sougakoff W, Truffot-Pernot C, Jarlier V: Characterization of new mutations in pyrazinamide resistant strains of Mycobacterium tuberculosis and identification of conserved regions important for the catalytic activity of the pyrazinamidase pncA. Antimicrob Agents Chemother 1999;43:1761-1763.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1761-1763
    • Lemaitre, N.1    Sougakoff, W.2    Truffot-Pernot, C.3    Jarlier, V.4
  • 55
    • 0037252098 scopus 로고    scopus 로고
    • The curious characteristics of pyrazinamide: a review
    • Zhang Y, Mitchison D: The curious characteristics of pyrazinamide: a review. Int J Tuberc Lung Dis 2003;7:6-21.
    • (2003) Int J Tuberc Lung Dis , vol.7 , pp. 6-21
    • Zhang, Y.1    Mitchison, D.2
  • 57
    • 33646053127 scopus 로고    scopus 로고
    • Stepwise decrease in moxifloxacin susceptibility amongst clinical isolates of multidrug-resistant Mycobacterium tuberculosis:correlation with ofloxacin susceptibility
    • Kam KM, Yip CW, Cheung TL, Tang HS, Leung OC, Chan MY: Stepwise decrease in moxifloxacin susceptibility amongst clinical isolates of multidrug-resistant Mycobacterium tuberculosis:correlation with ofloxacin susceptibility. Microb Drug Res 2006;12:7-11.
    • (2006) Microb Drug Res , vol.12 , pp. 7-11
    • Kam, K.M.1    Yip, C.W.2    Cheung, T.L.3    Tang, H.S.4    Leung, O.C.5    Chan, M.Y.6
  • 60
    • 48749107928 scopus 로고    scopus 로고
    • Mutagenesis in the 34 GyrA helix and in the toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones
    • Matrat S, Aubry A, Mayer C, Jarlier V, Cambau E: Mutagenesis in the 34 GyrA helix and in the toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones. Antimicrob Agents Chemother 2008;52:2909-2914.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2909-2914
    • Matrat, S.1    Aubry, A.2    Mayer, C.3    Jarlier, V.4    Cambau, E.5
  • 63
    • 0030003258 scopus 로고    scopus 로고
    • Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population
    • Meier A, Heifets L, Wallace RJ Jr, Zhang Y, Brown BA, Sander P, Böttger EC: Molecular mechanisms of clarithromycin resistance in Mycobacterium avium: observation of multiple 23S rDNA mutations in a clonal population. J Infect Dis 1996;174:354-360.
    • (1996) J Infect Dis , vol.174 , pp. 354-360
    • Meier, A.1    Heifets, L.2    Wallace Jr, R.J.3    Zhang, Y.4    Brown, B.A.5    Sander, P.6    Böttger, E.C.7
  • 64
    • 0034662963 scopus 로고    scopus 로고
    • Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis
    • De Barber AE, Mdluli K, Bosman M, Bekker, LG, Barry CE 3rd: Ethionamide activation and sensitivity in multidrug-resistant Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2000;97:9677-9682.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9677-9682
    • De Barber, A.E.1    Mdluli, K.2    Bosman, M.3    Bekker, L.G.4    Barry, C.E.5
  • 68
    • 0027489149 scopus 로고
    • Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alteration of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot
    • Finken M, Kirschner P, Meier A, Wrede A, Böttger EC: Molecular basis of streptomycin resistance in Mycobacterium tuberculosis: alteration of the ribosomal protein S12 gene and point mutations within a functional 16S ribosomal RNA pseudoknot. Mol Microbiol 1993;9:1239-1246.
    • (1993) Mol Microbiol , vol.9 , pp. 1239-1246
    • Finken, M.1    Kirschner, P.2    Meier, A.3    Wrede, A.4    Böttger, E.C.5
  • 69
    • 0029800114 scopus 로고    scopus 로고
    • Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon
    • Sander P, Prammananan T, Böttger EC: Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA operon. Mol Microbiol 1996;22:841-848.
    • (1996) Mol Microbiol , vol.22 , pp. 841-848
    • Sander, P.1    Prammananan, T.2    Böttger, E.C.3
  • 71
    • 0031802176 scopus 로고    scopus 로고
    • A single 16S ribosomal RNA substitution is responsible for resistance to amikacin and other 2-deoxystreptamine aminoglycosides in Mycobacterium abscessus and Mycobacterium chelonae
    • Prammananan T, Sander P, Brown BA, Frischkorn K, Onyi GO, Zhang Y, Böttger EC, Wallace RJ Jr: A single 16S ribosomal RNA substitution is responsible for resistance to amikacin and other 2-deoxystreptamine aminoglycosides in Mycobacterium abscessus and Mycobacterium chelonae. J Infect Dis 1998;177:1573-1581.
    • (1998) J Infect Dis , vol.177 , pp. 1573-1581
    • Prammananan, T.1    Sander, P.2    Brown, B.A.3    Frischkorn, K.4    Onyi, G.O.5    Zhang, Y.6    Böttger, E.C.7    Wallace Jr, R.J.8
  • 72
    • 0022531262 scopus 로고
    • Mycobacteria possess a surprisingly small number of ribosomal RNA genes in relation to the size of their genome
    • Bercovier H, Kafri O, Sela S: Mycobacteria possess a surprisingly small number of ribosomal RNA genes in relation to the size of their genome. Biochem Biophys Res Commun 1986;136:1136-1141.
    • (1986) Biochem Biophys Res Commun , vol.136 , pp. 1136-1141
    • Bercovier, H.1    Kafri, O.2    Sela, S.3
  • 74
    • 0029861166 scopus 로고    scopus 로고
    • Correlation of molecular resistance mechanism and phenotypic resistance level in streptomycin-resistant M. tuberculosis
    • Meier A, Sander P, Schaper KJ, Scholz M, Böttger EC: Correlation of molecular resistance mechanism and phenotypic resistance level in streptomycin-resistant M. tuberculosis. Antimicrob Agents Chemother 1996;40:2452-2454.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2452-2454
    • Meier, A.1    Sander, P.2    Schaper, K.J.3    Scholz, M.4    Böttger, E.C.5
  • 76
    • 0029978270 scopus 로고    scopus 로고
    • Characterization of rpsL and rrs mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from diverse geographical localities
    • Sreevatsan S, Pan X, Stockbauer K, Williams D, Kreiswirth B, Musser JM: Characterization of rpsL and rrs mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from diverse geographical localities. Antimicrob Agents Chemother 1996;40:1024-1026.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1024-1026
    • Sreevatsan, S.1    Pan, X.2    Stockbauer, K.3    Williams, D.4    Kreiswirth, B.5    Musser, J.M.6
  • 77
    • 0029912436 scopus 로고    scopus 로고
    • Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from New York City
    • Cooksey RC, Morlock GP, McQueen A, Glickman SE, Crawford JT: Characterization of streptomycin resistance mechanisms among Mycobacterium tuberculosis isolates from New York City. Antimicrob Agents Chemother 1996;40:1186-1188.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1186-1188
    • Cooksey, R.C.1    Morlock, G.P.2    McQueen, A.3    Glickman, S.E.4    Crawford, J.T.5
  • 78
    • 33846678393 scopus 로고    scopus 로고
    • Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria
    • Okamoto S, Tamaru A, Nakajima C, Nishimura K, Tanaka Y, Tokuyama S, Suzuki Y, Ochi K: Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria. Mol Microbiol 2007;63:1096-1106.
    • (2007) Mol Microbiol , vol.63 , pp. 1096-1106
    • Okamoto, S.1    Tamaru, A.2    Nakajima, C.3    Nishimura, K.4    Tanaka, Y.5    Tokuyama, S.6    Suzuki, Y.7    Ochi, K.8
  • 79
    • 0031958711 scopus 로고    scopus 로고
    • Detection of kanamycin-resistant Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene
    • Suzuki Y, Katsukava C, Tamaru A, Abe C, Makino M, Mizuguchi Y, Taniguchi H: Detection of kanamycin-resistant Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene. J Clin Micobiol 1998;36:1220-1225.
    • (1998) J Clin Micobiol , vol.36 , pp. 1220-1225
    • Suzuki, Y.1    Katsukava, C.2    Tamaru, A.3    Abe, C.4    Makino, M.5    Mizuguchi, Y.6    Taniguchi, H.7
  • 81
    • 23044445646 scopus 로고    scopus 로고
    • Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis
    • Maus CE, Plikaytis BB, Shinnick TM: Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2005;49:3192-3197.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3192-3197
    • Maus, C.E.1    Plikaytis, B.B.2    Shinnick, T.M.3
  • 82
    • 71249164165 scopus 로고    scopus 로고
    • High level of cross-resistance between kanamycin, amikacin, and capreomycin among Mycobacterium tuberculosis isolates from Georgia and a close relation with mutations in the rrs gene
    • Jugheli L, Bzekalava N, de Rijk P, Fissette K, Portaels F, Rigouts L: High level of cross-resistance between kanamycin, amikacin, and capreomycin among Mycobacterium tuberculosis isolates from Georgia and a close relation with mutations in the rrs gene. Antimicrob Agents Chemother 2009;53:5064-5068.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 5064-5068
    • Jugheli, L.1    Bzekalava, N.2    de Rijk, P.3    Fissette, K.4    Portaels, F.5    Rigouts, L.6
  • 83
    • 73949102884 scopus 로고    scopus 로고
    • Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis
    • Zaunbrecher MA, Sikes RD, Metchock B, Shinnick TM, Posey JE: Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis. Proc Natl Acad Sci USA 2009;106:20004-20009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20004-20009
    • Zaunbrecher, M.A.1    Sikes, R.D.2    Metchock, B.3    Shinnick, T.M.4    Posey, J.E.5
  • 85
    • 0014022758 scopus 로고
    • In-vitro and in-vivo laboratory studies on the antituberculous activity of capreomycin
    • Sutton WB, Gordee RS, Wick WE, Stanfield L: In-vitro and in-vivo laboratory studies on the antituberculous activity of capreomycin. Ann NY Acad Sci 1966;135:947-959.
    • (1966) Ann NY Acad Sci , vol.135 , pp. 947-959
    • Sutton, W.B.1    Gordee, R.S.2    Wick, W.E.3    Stanfield, L.4
  • 86
    • 0017165021 scopus 로고
    • Dual actions of viomycin on the ribosomal functions
    • Liou YF, Tanaka N: Dual actions of viomycin on the ribosomal functions. Biochem Biophys Res Commun 1976;71:477-483.
    • (1976) Biochem Biophys Res Commun , vol.71 , pp. 477-483
    • Liou, Y.F.1    Tanaka, N.2
  • 87
    • 33746106088 scopus 로고    scopus 로고
    • Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs
    • Johansen SK, Maus CE, Plikaytis BB, Douthwaite S: Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell 2006;23:173-182.
    • (2006) Mol Cell , vol.23 , pp. 173-182
    • Johansen, S.K.1    Maus, C.E.2    Plikaytis, B.B.3    Douthwaite, S.4
  • 88
    • 77949266567 scopus 로고    scopus 로고
    • The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
    • Stanley RE, Blaha G, Grodzicki RL, Strickler MD, Steitz TA: The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat Struct Mol Biol 2010;17:289-293.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 289-293
    • Stanley, R.E.1    Blaha, G.2    Grodzicki, R.L.3    Strickler, M.D.4    Steitz, T.A.5
  • 89
    • 0014514419 scopus 로고
    • Cross-resistance relationships between capreomycin, kanamycin, and viomycin resistances in tubercle bacilli from patients
    • Tsukamura M: Cross-resistance relationships between capreomycin, kanamycin, and viomycin resistances in tubercle bacilli from patients. Am Rev Respir Dis 1969;99:780-782.
    • (1969) Am Rev Respir Dis , vol.99 , pp. 780-782
    • Tsukamura, M.1
  • 90
    • 0017330551 scopus 로고
    • Cross-resistance in M. tuberculosis to kanamycin, capreomycin and viomycin
    • McClatchy JK, Kanes W, Davidson PT, Moulding TS: Cross-resistance in M. tuberculosis to kanamycin, capreomycin and viomycin. Tubercle 1977;58:29-34.
    • (1977) Tubercle , vol.58 , pp. 29-34
    • McClatchy, J.K.1    Kanes, W.2    Davidson, P.T.3    Moulding, T.S.4
  • 91
    • 67749120061 scopus 로고    scopus 로고
    • Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment
    • Feuerriegel S, Cox HS, Zarkua N, Karimovich HA, Braker A, Rüsch-Gerdes S, Niemann S: Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment. Antimicrob Agents Chemother 2009;53:3353-3356.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3353-3356
    • Feuerriegel, S.1    Cox, H.S.2    Zarkua, N.3    Karimovich, H.A.4    Braker, A.5    Rüsch-Gerdes, S.6    Niemann, S.7
  • 92
    • 12944255782 scopus 로고    scopus 로고
    • Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis
    • Maus CE, Plikaytis BB, Shinnick TM: Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 2005;49:571-577.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 571-577
    • Maus, C.E.1    Plikaytis, B.B.2    Shinnick, T.M.3
  • 93
    • 77956041045 scopus 로고    scopus 로고
    • In vitro pharmacokinetic/pharmacodynamic models in antiinfective drug development: focus on TB
    • Vaddady PK, Lee RE, Meibohm B: In vitro pharmacokinetic/pharmacodynamic models in antiinfective drug development: focus on TB. Future Med Chem 2010;2:1355-1369.
    • (2010) Future Med Chem , vol.2 , pp. 1355-1369
    • Vaddady, P.K.1    Lee, R.E.2    Meibohm, B.3
  • 96
    • 0011793001 scopus 로고
    • The clinical significance of low degrees of drug resistance in pulmonary tuberculosis
    • Stewart SM, Crofton JW: The clinical significance of low degrees of drug resistance in pulmonary tuberculosis. Am Rev Respir Dis 1964;89:811-829.
    • (1964) Am Rev Respir Dis , vol.89 , pp. 811-829
    • Stewart, S.M.1    Crofton, J.W.2
  • 97
    • 0019434898 scopus 로고
    • Should isoniazid be used in retreatment of tuberculosis despite acquired isoniazid resistance?
    • Moulding TS: Should isoniazid be used in retreatment of tuberculosis despite acquired isoniazid resistance? Am Rev Respir Dis 1981;123:262-264.
    • (1981) Am Rev Respir Dis , vol.123 , pp. 262-264
    • Moulding, T.S.1
  • 98
  • 101
    • 73849167338 scopus 로고
    • Successful treatment of advanced isoniazid-and streptomycin-resistant pulmonary tuberculosis with ethionamide, pyrazinamide, and isoniazid
    • Petty TL, Mitchell RS: Successful treatment of advanced isoniazid-and streptomycin-resistant pulmonary tuberculosis with ethionamide, pyrazinamide, and isoniazid. Am Rev Respir Dis 1962;86:503-512.
    • (1962) Am Rev Respir Dis , vol.86 , pp. 503-512
    • Petty, T.L.1    Mitchell, R.S.2
  • 102
    • 0035925911 scopus 로고    scopus 로고
    • Drug resistant tuberculosis
    • Böttger EC: Drug resistant tuberculosis. Lancet 2001;357:1288-1289.
    • (2001) Lancet , vol.357 , pp. 1288-1289
    • Böttger, E.C.1
  • 103
    • 0004318230 scopus 로고    scopus 로고
    • Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes. Approved standard NCCLS document M24-A
    • Wayne, NCCLS
    • NCCLS: Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes. Approved standard NCCLS document M24-A. Wayne, NCCLS, 2003.
    • (2003)
  • 105
    • 0013816145 scopus 로고
    • Present aspects of bacterial resistance in tuberculosis
    • Canetti G: Present aspects of bacterial resistance in tuberculosis. Am Rev Respir Dis 1965;92:687-703.
    • (1965) Am Rev Respir Dis , vol.92 , pp. 687-703
    • Canetti, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.