Allelic exchange and mutant selection demonstrate that common clinical embCAB gene mutations only modestly increase resistance to ethambutol in Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy

Volumn 54, Issue 1, 2010, Pages 103-108

  Safi, Hassan ^a   Fleischmann, Robert D ^b   Peterson, Scott N ^b   Jones, Marcus B ^b   Jarrahi, Behnam ^b   Alland, David ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b J CRAIG VENTER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHAMBUTOL; ISONIAZID; RIFAMPICIN;

ALLELE; ARTICLE; BACTERIAL GENE; EMBB GENE; GENE IDENTIFICATION; GENE MUTATION; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL;

ALLELES; ANTITUBERCULAR AGENTS; CODON; DNA PRIMERS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ETHAMBUTOL; GENES, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MUTATION; MYCOBACTERIUM TUBERCULOSIS; OPERON; PENTOSYLTRANSFERASES; PLASMIDS; RIFAMPIN;

EID: 73849116052     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01288-09     Document Type: Article

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