Inhibition of histone deacetylases protects septic mice from lung and splenic apoptosis

Journal of Surgical Research

Volumn 187, Issue 2, 2014, Pages 559-570

  Takebe, Mariko ^a   Oishi, Hirofumi ^a   Taguchi, Kumiko ^a   Aoki, Yuta ^a   Takashina, Michinori ^a   Tomita, Kengo ^a   Yokoo, Hiroki ^a   Takano, Yasuo ^b   Yamazaki, Mitsuaki ^a   Hattori, Yuichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b KANAGAWA CANCER CENTER   (Japan)

Author keywords

Apoptosis; Epigenetics; Histone deacetylase inhibitor; Lung inflammation; Polymicrobial sepsis

Indexed keywords

ANTIINFLAMMATORY AGENT; CG 200745; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H4; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALPROIC ACID; [(E) N 1 3 (DIMETHYLAMINO)PROPYL] N 8 HYDROXY 2 [(NAPHTHALENE 1 LOXY)METHYL]OCT 2 ENEDIAMIDE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; HISTONE ACETYLATION; LIGATION; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FAMILY; PUNCTURE; SEPSIS; SPLEEN; UPREGULATION;

APOPTOSIS; EPIGENETICS; HISTONE DEACETYLASE INHIBITOR; LUNG INFLAMMATION; POLYMICROBIAL SEPSIS;

ANIMALS; APOPTOSIS; EPIGENOMICS; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HYDROXAMIC ACIDS; LUNG; MALE; MICE; MICE, INBRED BALB C; NAPHTHALENES; PNEUMONIA; SEPSIS; SPLEEN;

EID: 84900553958     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2013.10.050     Document Type: Article

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