Priming by lipopolysaccharide exaggerates acute lung injury and mortality in responses to peptidoglycan through up-regulation of Toll-like receptor-2 expression in mice

Biochemical Pharmacology

Volumn 75, Issue 5, 2008, Pages 1065-1075

  Matsuda, Naoyuki ^a   Yamazaki, Hiromi ^a   Takano, Ken ichi ^a   Matsui, Kazuhiro ^a   Takano, Yasuo ^a   Kemmotsu, Osamu ^b   Hattori, Yuichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute lung injury; Lipopolysaccharide; Nuclear factor B; Peptidoglycan; Sepsis; Toll like receptors; Transcription factor decoy

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CELL WALL; BLOOD GAS; BLOOD VESSEL PERMEABILITY; BRONCHIOLE; CONTROLLED STUDY; GAS EXCHANGE; GENE EXPRESSION; GENETIC TRANSFECTION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INNATE IMMUNITY; LASER MICRODISSECTION; LUNG ALVEOLUS CELL; LUNG BLOOD VESSEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURVIVAL;

ANIMALS; BLOOD GAS ANALYSIS; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED BALB C; MORTALITY; NF-KAPPA B; PEPTIDOGLYCAN; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2; UP-REGULATION;

EID: 38949208811     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.10.036     Document Type: Article

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