Progranulin gene delivery protects dopaminergic neurons in a mouse model of Parkinson's disease

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Van Kampen, Jackalina M ^a,b   Baranowski, David ^a   Kay, Denis G ^a,b  

^a Neurodyn Inc   (Canada)

^b UNIVERSITY OF PRINCE EDWARD ISLAND   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE; LENTIVIRUS VECTOR; PROGRANULIN; GRN PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE MARKER; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; DRUG USE; GENE THERAPY; LOCOMOTION; MALE; MOTOR DYSFUNCTION; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PARKINSON DISEASE; PROGRANULIN GENE; PROTEIN EXPRESSION; VIRAL GENE DELIVERY SYSTEM; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECTS; GENE TRANSFER; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOTOR ACTIVITY; MPTP POISONING; PATHOLOGY;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; DOPAMINE; DOPAMINERGIC NEURONS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOTOR ACTIVITY; MPTP POISONING; PARKINSON DISEASE;

EID: 84900547297     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097032     Document Type: Article

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