-
1
-
-
0035369623
-
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A., Datta S.R., Greenberg M.E. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 2001, 11:297-305.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
2
-
-
0001496694
-
A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Burns R.S., Chiueh C.C., Markey S.P., Ebert M.H., Jacobowitz D.M., Kopin I.J. A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. U. S. A. 1983, 80:4546-4550.
-
(1983)
Proc. Natl. Acad. Sci. U. S. A.
, vol.80
, pp. 4546-4550
-
-
Burns, R.S.1
Chiueh, C.C.2
Markey, S.P.3
Ebert, M.H.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
3
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley L.C. The phosphoinositide 3-kinase pathway. Science 2002, 296:1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
4
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone M.H., Roy N., Stennicke H.R., Salvesen G.S., Franke T.F., Stanbridge E., Frisch S., Reed J.C. Regulation of cell death protease caspase-9 by phosphorylation. Science 1998, 282:1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
5
-
-
0018608356
-
Chronic Parkinsonism secondary to intravenous injection of meperidine analogues
-
Davis G.C., Williams A.C., Markey S.P., Ebert M.H., Caine E.D., Reichert C.M., Kopin I.J. Chronic Parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Res. 1979, 1:249-254.
-
(1979)
Psychiatry Res.
, vol.1
, pp. 249-254
-
-
Davis, G.C.1
Williams, A.C.2
Markey, S.P.3
Ebert, M.H.4
Caine, E.D.5
Reichert, C.M.6
Kopin, I.J.7
-
6
-
-
33750600736
-
ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling
-
Di Segni A., Farin K., Pinkas-Kramarski R. ErbB4 activation inhibits MPP+-induced cell death in PC12-ErbB4 cells: involvement of PI3K and Erk signaling. J. Mol. Neurosci. 2006, 29:257-267.
-
(2006)
J. Mol. Neurosci.
, vol.29
, pp. 257-267
-
-
Di Segni, A.1
Farin, K.2
Pinkas-Kramarski, R.3
-
7
-
-
0037418614
-
Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease
-
Eberhardt O., Schulz J.B. Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease. Toxicol. Lett. 2003, 139:135-151.
-
(2003)
Toxicol. Lett.
, vol.139
, pp. 135-151
-
-
Eberhardt, O.1
Schulz, J.B.2
-
8
-
-
0037064274
-
Methylpyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells
-
Erik M.H., Jameel D., Paula M.K., Thomas W.S., Jeremy B.T., James P.B. Methylpyridinium (MPP+)- and nerve growth factor-induced changes in pro- and anti-apoptotic signaling pathways in SH-SY5Y neuroblastoma cells. Brain Res. 2002, 952:98-110.
-
(2002)
Brain Res.
, vol.952
, pp. 98-110
-
-
Erik, M.H.1
Jameel, D.2
Paula, M.K.3
Thomas, W.S.4
Jeremy, B.T.5
James, P.B.6
-
9
-
-
76749088358
-
Pathological roles of MAPK signaling pathways in human diseases
-
Eun K.K., Eui J.C. Pathological roles of MAPK signaling pathways in human diseases. Biochim. Biophys. Acta 2010, 1802:396-405.
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 396-405
-
-
Eun, K.K.1
Eui, J.C.2
-
10
-
-
0021280826
-
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice
-
Heikkila R.E., Hess A., Duvoisin R.C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science 1984, 224:1451-1453.
-
(1984)
Science
, vol.224
, pp. 1451-1453
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
11
-
-
0346422397
-
The neurotoxicant trimethyltin induces apoptosis via caspase activation, p38 protein kinase, and oxidative stress in PC12 cells
-
Jenkins S.M., Barone S. The neurotoxicant trimethyltin induces apoptosis via caspase activation, p38 protein kinase, and oxidative stress in PC12 cells. Toxicol. Lett. 2004, 147:63-72.
-
(2004)
Toxicol. Lett.
, vol.147
, pp. 63-72
-
-
Jenkins, S.M.1
Barone, S.2
-
12
-
-
34547775771
-
Protective effects of Ginkgo biloba extract on paraquat-induced apoptosis of PC12 cells
-
Kang X., Chen J., Xu Z., Li H., Wang B. Protective effects of Ginkgo biloba extract on paraquat-induced apoptosis of PC12 cells. Toxicol. In Vitro 2007, 21:1003-1009.
-
(2007)
Toxicol. In Vitro
, vol.21
, pp. 1003-1009
-
-
Kang, X.1
Chen, J.2
Xu, Z.3
Li, H.4
Wang, B.5
-
13
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
Kennedy S.G., Wagner A.J., Conzen S.D., Jordan J., Bellacosa A., Tsichlis P.N., Hay N. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev. 1997, 11:701-713.
-
(1997)
Genes Dev.
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordan, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
14
-
-
3543001698
-
Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells
-
Koh S.H., Kim S.H., Kwon H., Kim J.G., Kim J.H., Yang K.H., Kim J., Kim S.U., Yu H.J., Do B.R., Kim K.S., Jung H.K. Phosphatidylinositol-3 kinase/Akt and GSK-3 mediated cytoprotective effect of epigallocatechin gallate on oxidative stress-injured neuronal-differentiated N18D3 cells. Neurotoxicology 2004, 25:793-802.
-
(2004)
Neurotoxicology
, vol.25
, pp. 793-802
-
-
Koh, S.H.1
Kim, S.H.2
Kwon, H.3
Kim, J.G.4
Kim, J.H.5
Yang, K.H.6
Kim, J.7
Kim, S.U.8
Yu, H.J.9
Do, B.R.10
Kim, K.S.11
Jung, H.K.12
-
15
-
-
34447343340
-
Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP
-
Kou J., Bloomquist J.R. Neurotoxicity in murine striatal dopaminergic pathways following long-term application of low doses of permethrin and MPTP. Toxicol. Lett. 2007, 171:154-161.
-
(2007)
Toxicol. Lett.
, vol.171
, pp. 154-161
-
-
Kou, J.1
Bloomquist, J.R.2
-
16
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston J.W., Ballard P., Tetrud J.W., Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983, 219:979-980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
17
-
-
28444474253
-
Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice
-
Li X., Matsumoto K., Murakami Y., Tezuka Y., Wu Y., Kadota S. Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice. Pharmacol. Biochem. Behav. 2005, 82:345-352.
-
(2005)
Pharmacol. Biochem. Behav.
, vol.82
, pp. 345-352
-
-
Li, X.1
Matsumoto, K.2
Murakami, Y.3
Tezuka, Y.4
Wu, Y.5
Kadota, S.6
-
18
-
-
77956124557
-
Tetrahydroxystilbene glucoside attenuates MPP+-induced apoptosis in PC12 cells by inhibiting ROS generation and modulating JNK activation
-
Li X., Li Y., Chen J., Sun J., Li Xi., Sun X., Kang X. Tetrahydroxystilbene glucoside attenuates MPP+-induced apoptosis in PC12 cells by inhibiting ROS generation and modulating JNK activation. Neurosci. Lett. 2010, 483:1-5.
-
(2010)
Neurosci. Lett.
, vol.483
, pp. 1-5
-
-
Li, X.1
Li, Y.2
Chen, J.3
Sun, J.4
Li, X.5
Sun, X.6
Kang, X.7
-
19
-
-
0034624017
-
The Parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity
-
Lotharius J., O'Malley K.L. The Parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity. J. Biol. Chem. 2000, 275:38581-38588.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38581-38588
-
-
Lotharius, J.1
O'Malley, K.L.2
-
20
-
-
0034746573
-
Akt1/PKBα protects PC12 cells against the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals
-
Marta S., Daniel M., Alberto A., Antonio C. Akt1/PKBα protects PC12 cells against the Parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium and reduces the levels of oxygen-free radicals. Mol. Cell. Neurosci. 2001, 17:67-77.
-
(2001)
Mol. Cell. Neurosci.
, vol.17
, pp. 67-77
-
-
Marta, S.1
Daniel, M.2
Alberto, A.3
Antonio, C.4
-
21
-
-
0029847052
-
Cyanide-induced apoptosis and oxidative stress in differentiated PC12 cells
-
Mills E.M., Gunasekar P.G., Pavlakovic G., Isom G.E. Cyanide-induced apoptosis and oxidative stress in differentiated PC12 cells. J. Neurochem. 1996, 67:1039-1046.
-
(1996)
J. Neurochem.
, vol.67
, pp. 1039-1046
-
-
Mills, E.M.1
Gunasekar, P.G.2
Pavlakovic, G.3
Isom, G.E.4
-
22
-
-
0035044196
-
Activation of nuclear transcription factor kappa B (NF-kappaB) is essential for dopamine-induced apoptosis in PC12 cells
-
Panet H., Barzilai A., Daily D., Melamed E., Offen D. Activation of nuclear transcription factor kappa B (NF-kappaB) is essential for dopamine-induced apoptosis in PC12 cells. J. Neurochem. 2001, 77:391-398.
-
(2001)
J. Neurochem.
, vol.77
, pp. 391-398
-
-
Panet, H.1
Barzilai, A.2
Daily, D.3
Melamed, E.4
Offen, D.5
-
23
-
-
4344622460
-
Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate
-
Radad K., Gille G., Moldzio R., Saito H., Rausch W.D. Ginsenosides Rb1 and Rg1 effects on mesencephalic dopaminergic cells stressed with glutamate. Brain Res. 2004, 1021:41-53.
-
(2004)
Brain Res.
, vol.1021
, pp. 41-53
-
-
Radad, K.1
Gille, G.2
Moldzio, R.3
Saito, H.4
Rausch, W.D.5
-
24
-
-
0036782149
-
The radical scavenging effects of stilbene glucosides from Polygonum multiflorum
-
Ryu G., Ju J.H., Park Y.J., Ryu S.Y., Choi B.W., Lee B.H. The radical scavenging effects of stilbene glucosides from Polygonum multiflorum. Arch. Pharm. Res. 2002, 25:636-639.
-
(2002)
Arch. Pharm. Res.
, vol.25
, pp. 636-639
-
-
Ryu, G.1
Ju, J.H.2
Park, Y.J.3
Ryu, S.Y.4
Choi, B.W.5
Lee, B.H.6
-
25
-
-
0026092049
-
Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: a model for neurotoxicological studies
-
Shafer T.J., Atchison W.D. Transmitter, ion channel and receptor properties of pheochromocytoma (PC12) cells: a model for neurotoxicological studies. Neurotoxicology 1991, 12:473-492.
-
(1991)
Neurotoxicology
, vol.12
, pp. 473-492
-
-
Shafer, T.J.1
Atchison, W.D.2
-
26
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G., Ouyang G., Bao S. The activation of Akt/PKB signaling pathway and cell survival. J. Cell. Mol. Med. 2005, 9:59-71.
-
(2005)
J. Cell. Mol. Med.
, vol.9
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
27
-
-
70350347175
-
Akt signal transduction dysfunction in Parkinson's disease
-
Suzanne T., Meghan F.C., Aileen M.M., Cora O' N. Akt signal transduction dysfunction in Parkinson's disease. Neuroscience 2009, 467:30-35.
-
(2009)
Neuroscience
, vol.467
, pp. 30-35
-
-
Suzanne, T.1
Meghan, F.C.2
Aileen, M.M.3
Cora O', N.4
-
28
-
-
0036229947
-
Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn. NGF-differentiated PC-12 cells
-
Tatton W.G., Chalmers-Redman R.M., Ju W.J., Mammen M., Carlile G.W., Pong A.W., Tatton N.A. Propargylamines induce antiapoptotic new protein synthesis in serum- and nerve growth factor (NGF)-withdrawn. NGF-differentiated PC-12 cells. J. Pharmacol. Exp. Ther. 2002, 301:753-764.
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.301
, pp. 753-764
-
-
Tatton, W.G.1
Chalmers-Redman, R.M.2
Ju, W.J.3
Mammen, M.4
Carlile, G.W.5
Pong, A.W.6
Tatton, N.A.7
-
29
-
-
0024470369
-
Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion
-
Tuler S.M., Hazen A.A., Bowen J.M. Release and metabolism of dopamine in a clonal line of pheochromocytoma (PC12) cells exposed to fenthion. Fundam. Appl. Toxicol. 1989, 13:484-492.
-
(1989)
Fundam. Appl. Toxicol.
, vol.13
, pp. 484-492
-
-
Tuler, S.M.1
Hazen, A.A.2
Bowen, J.M.3
-
30
-
-
10444276598
-
Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-l-carnitine
-
Virmani A., Gaetani F., Binienda Z., Xu A., Duhart H., Ali S.F. Role of mitochondrial dysfunction in neurotoxicity of MPP+: partial protection of PC12 cells by acetyl-l-carnitine. Ann. N. Y. Acad. Sci. 2004, 1025:267-273.
-
(2004)
Ann. N. Y. Acad. Sci.
, vol.1025
, pp. 267-273
-
-
Virmani, A.1
Gaetani, F.2
Binienda, Z.3
Xu, A.4
Duhart, H.5
Ali, S.F.6
-
31
-
-
36249032488
-
Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats
-
Wang R., Tang Y., Feng B., Ye C., Fang L., Zhang L., Li L. Changes in hippocampal synapses and learning-memory abilities in age-increasing rats and effects of tetrahydroxystilbene glucoside in aged rats. Neuroscience 2007, 149:739-746.
-
(2007)
Neuroscience
, vol.149
, pp. 739-746
-
-
Wang, R.1
Tang, Y.2
Feng, B.3
Ye, C.4
Fang, L.5
Zhang, L.6
Li, L.7
-
32
-
-
67349106386
-
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK. SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation
-
Wang T., Gu J., Wu P.F., Wang F., Xiong Z., Yang Y.J., Wu W.N., Dong L.D., Chen J.G. Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK. SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radic. Biol. Med. 2009, 47:229-240.
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 229-240
-
-
Wang, T.1
Gu, J.2
Wu, P.F.3
Wang, F.4
Xiong, Z.5
Yang, Y.J.6
Wu, W.N.7
Dong, L.D.8
Chen, J.G.9
-
33
-
-
13544271144
-
JNK inhibition as a potential strategy in treating Parkinson's disease
-
Wang W., Ma C., Mao Z., Li M. JNK inhibition as a potential strategy in treating Parkinson's disease. Drug News Perspect. 2004, 17:646-654.
-
(2004)
Drug News Perspect.
, vol.17
, pp. 646-654
-
-
Wang, W.1
Ma, C.2
Mao, Z.3
Li, M.4
-
34
-
-
65949102322
-
Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity
-
Wang W., Sun F., An Y., Ai H., Zhang L., Huang W., Li L. Morroniside protects human neuroblastoma SH-SY5Y cells against hydrogen peroxide-induced cytotoxicity. Eur. J. Pharmacol. 2009, 613:19-23.
-
(2009)
Eur. J. Pharmacol.
, vol.613
, pp. 19-23
-
-
Wang, W.1
Sun, F.2
An, Y.3
Ai, H.4
Zhang, L.5
Huang, W.6
Li, L.7
-
35
-
-
33747886787
-
Progress of study on brain protective effect and mechanism of Polygonum multiflorum
-
Wang W., Wang D.Q. Progress of study on brain protective effect and mechanism of Polygonum multiflorum. Zhongguo Zhong Xi Yi Jie He Za Zhi 2005, 25:955-959.
-
(2005)
Zhongguo Zhong Xi Yi Jie He Za Zhi
, vol.25
, pp. 955-959
-
-
Wang, W.1
Wang, D.Q.2
-
36
-
-
37349124150
-
Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice
-
Wang X., Zhao L., Han T., Chen S., Wang J. Protective effects of 2,3,5,4'-tetrahydroxystilbene-2-O-beta-d-glucoside, an active component of Polygonum multiflorum Thunb, on experimental colitis in mice. Eur. J. Pharmacol. 2008, 578:339-348.
-
(2008)
Eur. J. Pharmacol.
, vol.578
, pp. 339-348
-
-
Wang, X.1
Zhao, L.2
Han, T.3
Chen, S.4
Wang, J.5
-
37
-
-
73449103155
-
NF-κB mediates MPP+-induced apoptotic cell death in neuroblastoma cells SH-EP1 through JNK and c-Jun/AP-1
-
Yang H., Wang L., Xia Y., Chang P., Feng Z. NF-κB mediates MPP+-induced apoptotic cell death in neuroblastoma cells SH-EP1 through JNK and c-Jun/AP-1. Neurochem. Int. 2010, 56:128-134.
-
(2010)
Neurochem. Int.
, vol.56
, pp. 128-134
-
-
Yang, H.1
Wang, L.2
Xia, Y.3
Chang, P.4
Feng, Z.5
-
38
-
-
34249747700
-
Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells
-
Zhang L., Yu H., Sun Y., Lin X., Chen B., Tan C., Cao G., Wang Z. Protective effects of salidroside on hydrogen peroxide-induced apoptosis in SH-SY5Y human neuroblastoma cells. Eur. J. Pharmacol. 2007, 564:18-25.
-
(2007)
Eur. J. Pharmacol.
, vol.564
, pp. 18-25
-
-
Zhang, L.1
Yu, H.2
Sun, Y.3
Lin, X.4
Chen, B.5
Tan, C.6
Cao, G.7
Wang, Z.8
-
39
-
-
38549095164
-
6,7-di-O-Glucopyranosyl-esculetin protects SH-SY5Y cells from dopamine-induced cytotoxicity
-
Zhao D.L., Zou L.B., Lin S., Shi J.G., Zhu H.B. 6,7-di-O-Glucopyranosyl-esculetin protects SH-SY5Y cells from dopamine-induced cytotoxicity. Eur. J. Pharmacol. 2008, 580:329-338.
-
(2008)
Eur. J. Pharmacol.
, vol.580
, pp. 329-338
-
-
Zhao, D.L.1
Zou, L.B.2
Lin, S.3
Shi, J.G.4
Zhu, H.B.5
|