Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in Hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells

Journal of Biological Chemistry

Volumn 289, Issue 19, 2014, Pages 13476-13491

  Usatyuk, Peter V ^a   Fu, Panfeng ^a   Mohan, Vijay ^a   Epshtein, Yulia ^a   Jacobson, Jeffrey R ^a   Gomez Cambronero, Julian ^c   Wary, Kishore K ^a   Bindokas, Vytas ^b   Dudek, Steven M ^a   Salgia, Ravi ^b   Garcia, Joe G N ^a   Natarajan, Viswanathan ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c WRIGHT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BLOOD VESSELS; CELL PROLIFERATION; ENDOTHELIAL CELLS; ENZYMES; PHOSPHORYLATION; SIGNALING;

AKT PHOSPHORYLATION; CELL MIGRATION; DOSE-DEPENDENT MANNER; HEPATOCYTE GROWTH FACTOR; MICROVASCULAR ENDOTHELIAL CELLS; REACTIVE OXYGEN SPECIES; ROS GENERATIONS; TUMORIGENESIS;

CELL SIGNALING;

2 MORPHOLINO 8 PHENYLCHROMONE; ACTIN; C MET KINASE; CORTACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; PROTEIN P47; RAC1 PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EX VIVO STUDY; GENE TRANSLOCATION; HUMAN; HUMAN CELL; HUMAN LUNG MICROVASCULAR ENDOTHELIAL CELL; LAMELLIPODIUM; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASCULAR RING;

AKT; CELL MIGRATION; ENDOTHELIAL CELL; HEPATOCYTE GROWTH FACTOR; NADPH OXIDASE;

ANIMALS; CELLS, CULTURED; ENDOTHELIAL CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; LUNG; MICE; NADPH OXIDASE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; PSEUDOPODIA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84900465261     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.527556     Document Type: Article

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