메뉴 건너뛰기




Volumn 112, Issue 9, 2013, Pages 1272-1287

Regulation of endothelial cell differentiation and specification

Author keywords

arterio venous specification; endothelial cells; hemogenic endothelium; lymphatic endothelium

Indexed keywords

ANGIOGENESIS; CELL DIFFERENTIATION; CELL SPECIFICITY; CELL TYPE; ENDOTHELIUM CELL; HEMANGIOBLAST; HEMATOPOIETIC STEM CELL; HUMAN; LYMPHANGIOGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION; STEM CELL;

EID: 84877259309     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.300506     Document Type: Review
Times cited : (231)

References (187)
  • 1
    • 0032427448 scopus 로고    scopus 로고
    • Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo
    • Belaoussoff M, Farrington SM, Baron MH. Hematopoietic induction and respecification of A-P identity by visceral endoderm signaling in the mouse embryo. Development. 1998;125:5009-5018.
    • (1998) Development , vol.125 , pp. 5009-5018
    • Belaoussoff, M.1    Farrington, S.M.2    Baron, M.H.3
  • 2
    • 0036336871 scopus 로고    scopus 로고
    • Endoderm is required for vascular endothelial tube formation, but not for angioblast specification
    • Vokes SA, Krieg PA. Endoderm is required for vascular endothelial tube formation, but not for angioblast specification. Development. 2002;129:775-785.
    • (2002) Development , vol.129 , pp. 775-785
    • Vokes, S.A.1    Krieg, P.A.2
  • 3
    • 0018652784 scopus 로고
    • Marginal zone cells-The primitive streak-inducing component of the primary hypoblast in the chick
    • Azar Y, Eyal-Giladi H. Marginal zone cells-the primitive streak-inducing component of the primary hypoblast in the chick. J Embryol Exp Morphol. 1979;52:79-88.
    • (1979) J Embryol Exp Morphol , vol.52 , pp. 79-88
    • Azar, Y.1    Eyal-Giladi, H.2
  • 4
    • 20444408361 scopus 로고    scopus 로고
    • Temporal analysis of the early BMP functions identifies distinct anti-organizer and mesoderm patterning phases
    • Marom K, Levy V, Pillemer G, Fainsod A. Temporal analysis of the early BMP functions identifies distinct anti-organizer and mesoderm patterning phases. Dev Biol. 2005;282:442-454.
    • (2005) Dev Biol , vol.282 , pp. 442-454
    • Marom, K.1    Levy, V.2    Pillemer, G.3    Fainsod, A.4
  • 5
    • 0033616605 scopus 로고    scopus 로고
    • Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2
    • Saxton TM, Pawson T. Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2. Proc Natl Acad Sci USA. 1999;96:3790-3795.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3790-3795
    • Saxton, T.M.1    Pawson, T.2
  • 6
    • 0032908432 scopus 로고    scopus 로고
    • Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects
    • Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk MM, Zwijsen A. Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999;126:1631-1642.
    • (1999) Development , vol.126 , pp. 1631-1642
    • Chang, H.1    Huylebroeck, D.2    Verschueren, K.3    Guo, Q.4    Matzuk, M.M.5    Zwijsen, A.6
  • 8
    • 0028582035 scopus 로고
    • FGFr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation
    • Yamaguchi TP, Harpal K, Henkemeyer M, Rossant J. FGFr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev. 1994;8:3032-3044.
    • (1994) Genes Dev , vol.8 , pp. 3032-3044
    • Yamaguchi, T.P.1    Harpal, K.2    Henkemeyer, M.3    Rossant, J.4
  • 9
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1-and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • Park C, Afrikanova I, Chung YS, Zhang WJ, Arentson E, Fong Gh Gh, Rosendahl A, Choi K. A hierarchical order of factors in the generation of FLK1-and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development. 2004;131:2749-2762.
    • (2004) Development , vol.131 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3    Zhang, W.J.4    Arentson, E.5    Gh Gh, F.6    Rosendahl, A.7    Choi, K.8
  • 10
    • 44449152487 scopus 로고    scopus 로고
    • The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF
    • Pearson S, Sroczynska P, Lacaud G, Kouskoff V. The stepwise specification of embryonic stem cells to hematopoietic fate is driven by sequential exposure to Bmp4, activin A, bFGF and VEGF. Development. 2008;135:1525-1535.
    • (2008) Development , vol.135 , pp. 1525-1535
    • Pearson, S.1    Sroczynska, P.2    Lacaud, G.3    Kouskoff, V.4
  • 11
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
    • Winnier G, Blessing M, Labosky PA, Hogan BL. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 1995;9:2105-2116.
    • (1995) Genes Dev , vol.9 , pp. 2105-2116
    • Winnier, G.1    Blessing, M.2    Labosky, P.A.3    Hogan, B.L.4
  • 12
    • 0032584068 scopus 로고    scopus 로고
    • The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
    • Yang X, Li C, Xu X, Deng C. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc Natl Acad Sci USA. 1998;95:3667-3672.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3667-3672
    • Yang, X.1    Li, C.2    Xu, X.3    Deng, C.4
  • 13
    • 0026469319 scopus 로고
    • Induction of vasculogenesis and hematopoiesis in vitro
    • Flamme I, Risau W. Induction of vasculogenesis and hematopoiesis in vitro. Development. 1992;116:435-439.
    • (1992) Development , vol.116 , pp. 435-439
    • Flamme, I.1    Risau, W.2
  • 14
    • 0032402116 scopus 로고    scopus 로고
    • Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm
    • Huber TL, Zhou Y, Mead PE, Zon LI. Cooperative effects of growth factors involved in the induction of hematopoietic mesoderm. Blood. 1998;92:4128-4137.
    • (1998) Blood , vol.92 , pp. 4128-4137
    • Huber, T.L.1    Zhou, Y.2    Mead, P.E.3    Zon, L.I.4
  • 15
    • 65549120788 scopus 로고    scopus 로고
    • Signaling hierarchy regulating human endothelial cell development
    • Kelly MA, Hirschi KK. Signaling hierarchy regulating human endothelial cell development. Arterioscler Thromb Vasc Biol. 2009;29:718-724.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 718-724
    • Kelly, M.A.1    Hirschi, K.K.2
  • 17
    • 0028868619 scopus 로고
    • Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development
    • Breier G, Clauss M, Risau W. Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn. 1995;204:228-239.
    • (1995) Dev Dyn , vol.204 , pp. 228-239
    • Breier, G.1    Clauss, M.2    Risau, W.3
  • 19
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996;380:435-439.
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breier, G.3
  • 20
    • 0033793921 scopus 로고    scopus 로고
    • Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression
    • Miquerol L, Langille BL, Nagy A. Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression. Development. 2000;127:3941-3946.
    • (2000) Development , vol.127 , pp. 3941-3946
    • Miquerol, L.1    Langille, B.L.2    Nagy, A.3
  • 22
    • 0033515089 scopus 로고    scopus 로고
    • In vitro hematopoietic and endothelial potential of flk-1(-/-) embryonic stem cells and embryos
    • Schuh AC, Faloon P, Hu QL, Bhimani M, Choi K. In vitro hematopoietic and endothelial potential of flk-1(-/-) embryonic stem cells and embryos. Proc Natl Acad Sci USA. 1999;96:2159-2164.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2159-2164
    • Schuh, A.C.1    Faloon, P.2    Hu, Q.L.3    Bhimani, M.4    Choi, K.5
  • 23
    • 34250214921 scopus 로고    scopus 로고
    • Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis
    • Dejana E, Taddei A, Randi AM. Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta. 2007;1775:298-312.
    • (2007) Biochim Biophys Acta , vol.1775 , pp. 298-312
    • Dejana, E.1    Taddei, A.2    Randi, A.M.3
  • 24
    • 59649110012 scopus 로고    scopus 로고
    • Transcriptional control of endothelial cell development
    • De Val S, Black BL. Transcriptional control of endothelial cell development. Dev Cell. 2009;16:180-195.
    • (2009) Dev Cell , vol.16 , pp. 180-195
    • De Val, S.1    Black, B.L.2
  • 25
    • 31144445013 scopus 로고    scopus 로고
    • Ets1-related protein is a key regulator of vasculogenesis in zebrafish
    • Sumanas S, Lin S. Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol. 2006;4:e10.
    • (2006) PLoS Biol , vol.4
    • Sumanas, S.1    Lin, S.2
  • 27
    • 77949789065 scopus 로고    scopus 로고
    • ETS family protein ETV2 is required for initiation of the endothelial lineage but not the hematopoietic lineage in the Xenopus embryo
    • Salanga MC, Meadows SM, Myers CT, Krieg PA. ETS family protein ETV2 is required for initiation of the endothelial lineage but not the hematopoietic lineage in the Xenopus embryo. Dev Dyn. 2010;239:1178-1187.
    • (2010) Dev Dyn , vol.239 , pp. 1178-1187
    • Salanga, M.C.1    Meadows, S.M.2    Myers, C.T.3    Krieg, P.A.4
  • 29
    • 42649134047 scopus 로고    scopus 로고
    • Interplay among Etsrp/ER71 Scl and Alk8 signaling controls endothelial and myeloid cell formation
    • Sumanas S, Gomez G, Zhao Y, Park C, Choi K, Lin S. Interplay among Etsrp/ER71, Scl, and Alk8 signaling controls endothelial and myeloid cell formation. Blood. 2008;111:4500-4510.
    • (2008) Blood , vol.111 , pp. 4500-4510
    • Sumanas, S.1    Gomez, G.2    Zhao, Y.3    Park, C.4    Choi, K.5    Lin, S.6
  • 33
    • 84862878344 scopus 로고    scopus 로고
    • The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development
    • Wareing S, Mazan A, Pearson S, Göttgens B, Lacaud G, Kouskoff V. The Flk1-Cre-mediated deletion of ETV2 defines its narrow temporal requirement during embryonic hematopoietic development. Stem Cells. 2012;30:1521-1531.
    • (2012) Stem Cells , vol.30 , pp. 1521-1531
    • Wareing, S.1    Mazan, A.2    Pearson, S.3    Göttgens, B.4    Lacaud, G.5    Kouskoff, V.6
  • 36
    • 33744997209 scopus 로고    scopus 로고
    • In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility
    • Sakurai H, Era T, Jakt LM, Okada M, Nakai S, Nishikawa S, Nishikawa S. In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility. Stem Cells. 2006;24:575-586.
    • (2006) Stem Cells , vol.24 , pp. 575-586
    • Sakurai, H.1    Era, T.2    Jakt, L.M.3    Okada, M.4    Nakai, S.5    Nishikawa, S.6    Nishikawa, S.7
  • 38
    • 0033558087 scopus 로고    scopus 로고
    • Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2
    • Soldi R, Mitola S, Strasly M, Defilippi P, Tarone G, Bussolino F. Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J. 1999;18:882-892.
    • (1999) EMBO J , vol.18 , pp. 882-892
    • Soldi, R.1    Mitola, S.2    Strasly, M.3    Defilippi, P.4    Tarone, G.5    Bussolino, F.6
  • 39
    • 34748863572 scopus 로고    scopus 로고
    • Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis
    • Mahabeleshwar GH, Feng W, Reddy K, Plow EF, Byzova TV. Mechanisms of integrin-vascular endothelial growth factor receptor cross-activation in angiogenesis. Circ Res. 2007;101:570-580.
    • (2007) Circ Res , vol.101 , pp. 570-580
    • Mahabeleshwar, G.H.1    Feng, W.2    Reddy, K.3    Plow, E.F.4    Byzova, T.V.5
  • 40
    • 33644595058 scopus 로고    scopus 로고
    • Src Fyn and Yes play differential roles in VEGFmediated endothelial cell events
    • Werdich XQ, Penn JS. Src, Fyn and Yes play differential roles in VEGFmediated endothelial cell events. Angiogenesis. 2005;8:315-326.
    • (2005) Angiogenesis , vol.8 , pp. 315-326
    • Werdich, X.Q.1    Penn, J.S.2
  • 41
    • 0033393771 scopus 로고    scopus 로고
    • Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability
    • Eliceiri BP, Paul R, Schwartzberg PL, Hood JD, Leng J, Cheresh DA. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol Cell. 1999;4:915-924.
    • (1999) Mol Cell , vol.4 , pp. 915-924
    • Eliceiri, B.P.1    Paul, R.2    Schwartzberg, P.L.3    Hood, J.D.4    Leng, J.5    Cheresh, D.A.6
  • 42
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong GH, Rossant J, Gertsenstein M, Breitman ML. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 1995;376:66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 43
    • 0032764427 scopus 로고    scopus 로고
    • Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice
    • Fong GH, Zhang L, Bryce DM, Peng J. Increased hemangioblast commitment, not vascular disorganization, is the primary defect in flt-1 knock-out mice. Development. 1999;126:3015-3025.
    • (1999) Development , vol.126 , pp. 3015-3025
    • Fong, G.H.1    Zhang, L.2    Bryce, D.M.3    Peng, J.4
  • 45
    • 11144297756 scopus 로고    scopus 로고
    • Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice
    • Hiratsuka S, Nakao K, Nakamura K, Katsuki M, Maru Y, Shibuya M. Membrane fixation of vascular endothelial growth factor receptor 1 ligand-binding domain is important for vasculogenesis and angiogenesis in mice. Mol Cell Biol. 2005;25:346-354.
    • (2005) Mol Cell Biol , vol.25 , pp. 346-354
    • Hiratsuka, S.1    Nakao, K.2    Nakamura, K.3    Katsuki, M.4    Maru, Y.5    Shibuya, M.6
  • 46
    • 0032482978 scopus 로고    scopus 로고
    • Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice
    • Hiratsuka S, Minowa O, Kuno J, Noda T, Shibuya M. Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice. Proc Natl Acad Sci USA. 1998;95:9349-9354.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9349-9354
    • Hiratsuka, S.1    Minowa, O.2    Kuno, J.3    Noda, T.4    Shibuya, M.5
  • 47
    • 0032570774 scopus 로고    scopus 로고
    • Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors
    • Kondo K, Hiratsuka S, Subbalakshmi E, Matsushime H, Shibuya M. Genomic organization of the flt-1 gene encoding for vascular endothelial growth factor (VEGF) receptor-1 suggests an intimate evolutionary relationship between the 7-Ig and the 5-Ig tyrosine kinase receptors. Gene. 1998;208:297-305.
    • (1998) Gene , vol.208 , pp. 297-305
    • Kondo, K.1    Hiratsuka, S.2    Subbalakshmi, E.3    Matsushime, H.4    Shibuya, M.5
  • 48
    • 0033334764 scopus 로고    scopus 로고
    • Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity
    • He Y, Smith SK, Day KA, Clark DE, Licence DR, Charnock-Jones DS. Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocrinol. 1999;13:537-545.
    • (1999) Mol Endocrinol , vol.13 , pp. 537-545
    • He, Y.1    Smith, S.K.2    Day, K.A.3    Clark, D.E.4    Licence, D.R.5    Charnock-Jones, D.S.6
  • 49
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester G. Retinoic acid synthesis and signaling during early organogenesis. Cell. 2008;134:921-931.
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 50
    • 0345214518 scopus 로고    scopus 로고
    • Identification of a mechanism to localize generation of retinoic acid in rat embryos
    • Båvik C, Ward SJ, Ong DE. Identification of a mechanism to localize generation of retinoic acid in rat embryos. Mech Dev. 1997;69:155-167.
    • (1997) Mech Dev , vol.69 , pp. 155-167
    • Båvik, C.1    Ward, S.J.2    Ong, D.E.3
  • 51
    • 2642564628 scopus 로고    scopus 로고
    • Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation
    • Bohnsack BL, Lai L, Dolle P, Hirschi KK. Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation. Genes Dev. 2004;18:1345-1358.
    • (2004) Genes Dev , vol.18 , pp. 1345-1358
    • Bohnsack, B.L.1    Lai, L.2    Dolle, P.3    Hirschi, K.K.4
  • 52
    • 0346505180 scopus 로고    scopus 로고
    • Retinoic acid regulates endothelial cell proliferation during vasculogenesis
    • Lai L, Bohnsack BL, Niederreither K, Hirschi KK. Retinoic acid regulates endothelial cell proliferation during vasculogenesis. Development. 2003;130:6465-6474.
    • (2003) Development , vol.130 , pp. 6465-6474
    • Lai, L.1    Bohnsack, B.L.2    Niederreither, K.3    Hirschi, K.K.4
  • 53
    • 0032958632 scopus 로고    scopus 로고
    • Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
    • Niederreither K, Subbarayan V, Dollé P, Chambon P. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet. 1999;21:444-448.
    • (1999) Nat Genet , vol.21 , pp. 444-448
    • Niederreither, K.1    Subbarayan, V.2    Dollé, P.3    Chambon, P.4
  • 54
    • 0037203540 scopus 로고    scopus 로고
    • TGF-beta-dependent cell growth arrest and apoptosis
    • Lee KY, Bae SC. TGF-beta-dependent cell growth arrest and apoptosis. J Biochem Mol Biol. 2002;35:47-53.
    • (2002) J Biochem Mol Biol , vol.35 , pp. 47-53
    • Lee, K.Y.1    Bae, S.C.2
  • 55
    • 0028168242 scopus 로고
    • P15INK4B is a potential effector of TGF-betainduced cell cycle arrest
    • Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-betainduced cell cycle arrest. Nature. 1994;371:257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 56
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta
    • Reynisdóttir I, Polyak K, Iavarone A, Massagué J. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta. Genes Dev. 1995;9:1831-1845.
    • (1995) Genes Dev , vol.9 , pp. 1831-1845
    • Reynisdóttir, I.1    Polyak, K.2    Iavarone, A.3    Massagué, J.4
  • 57
    • 0030614715 scopus 로고    scopus 로고
    • The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2
    • Reynisdóttir I, Massagué J. The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. Genes Dev. 1997;11:492-503.
    • (1997) Genes Dev , vol.11 , pp. 492-503
    • Reynisdóttir, I.1    Massagué, J.2
  • 58
    • 0028179669 scopus 로고
    • P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev. 1994;8:9-22.
    • (1994) Genes Dev , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 59
    • 0035656786 scopus 로고    scopus 로고
    • Role of p27(Kip1) in cAMP-and TGF-beta2-mediated antiproliferation in rabbit corneal endothelial cells
    • Kim TY, Kim WI, Smith RE, Kay ED. Role of p27(Kip1) in cAMP-and TGF-beta2-mediated antiproliferation in rabbit corneal endothelial cells. Invest Ophthalmol Vis Sci. 2001;42:3142-3149.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 3142-3149
    • Kim, T.Y.1    Kim, W.I.2    Smith, R.E.3    Kay, E.D.4
  • 60
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;473:298-307.
    • (2011) Nature , vol.473 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 61
    • 34249689753 scopus 로고    scopus 로고
    • Molecular regulation of angiogenesis and lymphangiogenesis
    • Adams RH, Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat Rev Mol Cell Biol. 2007;8:464-478.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 464-478
    • Adams, R.H.1    Alitalo, K.2
  • 62
    • 84859608557 scopus 로고    scopus 로고
    • Hematopoietic stem cells: To be or Notch to be
    • Bigas A, Espinosa L. Hematopoietic stem cells: to be or Notch to be. Blood. 2012;119:3226-3235.
    • (2012) Blood , vol.119 , pp. 3226-3235
    • Bigas, A.1    Espinosa, L.2
  • 65
    • 33845907380 scopus 로고    scopus 로고
    • Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis
    • Ridgway J, Zhang G, Wu Y, et al. Inhibition of Dll4 signalling inhibits tumour growth by deregulating angiogenesis. Nature. 2006;444:1083-1087.
    • (2006) Nature , vol.444 , pp. 1083-1087
    • Ridgway, J.1    Zhang, G.2    Wu, Y.3
  • 69
    • 33847039645 scopus 로고    scopus 로고
    • Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
    • Siekmann AF, Lawson ND. Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries. Nature. 2007;445:781-784.
    • (2007) Nature , vol.445 , pp. 781-784
    • Siekmann, A.F.1    Lawson, N.D.2
  • 70
    • 20444495706 scopus 로고    scopus 로고
    • Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis
    • Sainson RC, Aoto J, Nakatsu MN, Holderfield M, Conn E, Koller E, Hughes CC. Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis. FASEB J. 2005;19:1027-1029.
    • (2005) FASEB J , vol.19 , pp. 1027-1029
    • Sainson, R.C.1    Aoto, J.2    Nakatsu, M.N.3    Holderfield, M.4    Conn, E.5    Koller, E.6    Hughes, C.C.7
  • 71
    • 33847046849 scopus 로고    scopus 로고
    • Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis
    • Hellström M, Phng LK, Hofmann JJ, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 2007;445:776-780.
    • (2007) Nature , vol.445 , pp. 776-780
    • Hellström, M.1    Phng, L.K.2    Hofmann, J.J.3
  • 72
    • 80053564674 scopus 로고    scopus 로고
    • VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling
    • Tammela T, Zarkada G, Nurmi H, et al. VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling. Nat Cell Biol. 2011;13:1202-1213.
    • (2011) Nat Cell Biol , vol.13 , pp. 1202-1213
    • Tammela, T.1    Zarkada, G.2    Nurmi, H.3
  • 82
    • 84868628036 scopus 로고    scopus 로고
    • Emerging role of micro-RNAs in the regulation of angiogenesis
    • Anand S, Cheresh DA. Emerging role of micro-RNAs in the regulation of angiogenesis. Genes Cancer. 2011;2:1134-1138.
    • (2011) Genes Cancer , vol.2 , pp. 1134-1138
    • Anand, S.1    Cheresh, D.A.2
  • 83
    • 34447632218 scopus 로고    scopus 로고
    • Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis
    • Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ Res. 2007;101:59-68.
    • (2007) Circ Res , vol.101 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3    Dimmeler, S.4
  • 86
    • 84857020975 scopus 로고    scopus 로고
    • MiR-221 is required for endothelial tip cell behaviors during vascular development
    • Nicoli S, Knyphausen CP, Zhu LJ, Lakshmanan A, Lawson ND. miR-221 is required for endothelial tip cell behaviors during vascular development. Dev Cell. 2012;22:418-429.
    • (2012) Dev Cell , vol.22 , pp. 418-429
    • Nicoli, S.1    Knyphausen, C.P.2    Zhu, L.J.3    Lakshmanan, A.4    Lawson, N.D.5
  • 89
    • 0032577446 scopus 로고    scopus 로고
    • Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4
    • Wang HU, Chen ZF, Anderson DJ. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998;93:741-753.
    • (1998) Cell , vol.93 , pp. 741-753
    • Wang, H.U.1    Chen, Z.F.2    Anderson, D.J.3
  • 90
    • 16244399549 scopus 로고    scopus 로고
    • Segregation of arterial and venous markers in subpopulations of blood islands before vessel formation
    • Herzog Y, Guttmann-Raviv N, Neufeld G. Segregation of arterial and venous markers in subpopulations of blood islands before vessel formation. Dev Dyn. 2005;232:1047-1055.
    • (2005) Dev Dyn , vol.232 , pp. 1047-1055
    • Herzog, Y.1    Guttmann-Raviv, N.2    Neufeld, G.3
  • 92
    • 0036070186 scopus 로고    scopus 로고
    • Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation
    • Lawson ND, Vogel AM, Weinstein BM. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell. 2002;3:127-136.
    • (2002) Dev Cell , vol.3 , pp. 127-136
    • Lawson, N.D.1    Vogel, A.M.2    Weinstein, B.M.3
  • 94
    • 33745099879 scopus 로고    scopus 로고
    • The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development
    • Seo S, Fujita H, Nakano A, Kang M, Duarte A, Kume T. The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol. 2006;294:458-470.
    • (2006) Dev Biol , vol.294 , pp. 458-470
    • Seo, S.1    Fujita, H.2    Nakano, A.3    Kang, M.4    Duarte, A.5    Kume, T.6
  • 95
    • 48749117994 scopus 로고    scopus 로고
    • Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells
    • Hayashi H, Kume T. Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells. PLoS One. 2008;3:e2401.
    • (2008) PLoS One , vol.3
    • Hayashi, H.1    Kume, T.2
  • 96
    • 33847054742 scopus 로고    scopus 로고
    • Functional arterial and venous fate is determined by graded VEGF signaling and notch status during embryonic stem cell differentiation
    • Lanner F, Sohl M, Farnebo F. Functional arterial and venous fate is determined by graded VEGF signaling and notch status during embryonic stem cell differentiation. Arterioscler Thromb Vasc Biol. 2007;27:487-493.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 487-493
    • Lanner, F.1    Sohl, M.2    Farnebo, F.3
  • 100
    • 84864052669 scopus 로고    scopus 로고
    • Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish
    • Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 2012;120:477-488.
    • (2012) Blood , vol.120 , pp. 477-488
    • Wilkinson, R.N.1    Koudijs, M.J.2    Patient, R.K.3    Ingham, P.W.4    Schulte-Merker, S.5    Van Eeden, F.J.6
  • 101
    • 18344377007 scopus 로고    scopus 로고
    • Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity
    • You LR, Lin FJ, Lee CT, DeMayo FJ, Tsai MJ, Tsai SY. Suppression of Notch signalling by the COUP-TFII transcription factor regulates vein identity. Nature. 2005;435:98-104.
    • (2005) Nature , vol.435 , pp. 98-104
    • You, L.R.1    Lin, F.J.2    Lee, C.T.3    Demayo, F.J.4    Tsai, M.J.5    Tsai, S.Y.6
  • 103
    • 0033578853 scopus 로고    scopus 로고
    • Prox1 function is required for the development of the murine lymphatic system
    • Wigle JT, Oliver G. Prox1 function is required for the development of the murine lymphatic system. Cell. 1999;98:769-778.
    • (1999) Cell , vol.98 , pp. 769-778
    • Wigle, J.T.1    Oliver, G.2
  • 107
    • 57349142376 scopus 로고    scopus 로고
    • Sox18 induces development of the lymphatic vasculature in mice
    • François M, Caprini A, Hosking B, et al. Sox18 induces development of the lymphatic vasculature in mice. Nature. 2008;456:643-647.
    • (2008) Nature , vol.456 , pp. 643-647
    • François, M.1    Caprini, A.2    Hosking, B.3
  • 109
    • 61849097153 scopus 로고    scopus 로고
    • Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate
    • Lee S, Kang J, Yoo J, Ganesan SK, Cook SC, Aguilar B, Ramu S, Lee J, Hong YK. Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate. Blood. 2009;113:1856-1859.
    • (2009) Blood , vol.113 , pp. 1856-1859
    • Lee, S.1    Kang, J.2    Yoo, J.3    Ganesan, S.K.4    Cook, S.C.5    Aguilar, B.6    Ramu, S.7    Lee, J.8    Hong, Y.K.9
  • 110
    • 77951847278 scopus 로고    scopus 로고
    • Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development
    • Lin FJ, Chen X, Qin J, Hong YK, Tsai MJ, Tsai SY. Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development. J Clin Invest. 2010;120:1694-1707.
    • (2010) J Clin Invest , vol.120 , pp. 1694-1707
    • Lin, F.J.1    Chen, X.2    Qin, J.3    Hong, Y.K.4    Tsai, M.J.5    Tsai, S.Y.6
  • 111
    • 77950469880 scopus 로고    scopus 로고
    • The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells
    • Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G. The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev. 2010;24:696-707.
    • (2010) Genes Dev , vol.24 , pp. 696-707
    • Srinivasan, R.S.1    Geng, X.2    Yang, Y.3    Wang, Y.4    Mukatira, S.5    Studer, M.6    Porto, M.P.7    Lagutin, O.8    Oliver, G.9
  • 112
    • 77957691035 scopus 로고    scopus 로고
    • Prox1 expression is negatively regulated by miR-181 in endothelial cells
    • Kazenwadel J, Michael MZ, Harvey NL. Prox1 expression is negatively regulated by miR-181 in endothelial cells. Blood. 2010;116:2395-2401.
    • (2010) Blood , vol.116 , pp. 2395-2401
    • Kazenwadel, J.1    Michael, M.Z.2    Harvey, N.L.3
  • 122
    • 77955982948 scopus 로고    scopus 로고
    • Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish
    • Geudens I, Herpers R, Hermans K, et al. Role of delta-like-4/Notch in the formation and wiring of the lymphatic network in zebrafish. Arterioscler Thromb Vasc Biol. 2010;30:1695-1702.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1695-1702
    • Geudens, I.1    Herpers, R.2    Hermans, K.3
  • 123
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J, Robertson S, Kennedy M, Wall C, Keller G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development. 1999;126:5073-5084.
    • (1999) Development , vol.126 , pp. 5073-5084
    • Palis, J.1    Robertson, S.2    Kennedy, M.3    Wall, C.4    Keller, G.5
  • 124
    • 0031048644 scopus 로고    scopus 로고
    • Initiation of murine embryonic erythropoiesis: A spatial analysis
    • Silver L, Palis J. Initiation of murine embryonic erythropoiesis: a spatial analysis. Blood. 1997;89:1154-1164.
    • (1997) Blood , vol.89 , pp. 1154-1164
    • Silver, L.1    Palis, J.2
  • 125
    • 0000462980 scopus 로고
    • Studies on the origin of bloodvessels and of red blood-corpuscles as seen in the living blastoderm of chicks during the second day of incubation
    • Sabin FR. Studies on the origin of bloodvessels and of red blood-corpuscles as seen in the living blastoderm of chicks during the second day of incubation. Contrib Embryol. 1920;9:215-262
    • (1920) Contrib Embryol , vol.9 , pp. 215-262
    • Sabin, F.R.1
  • 126
    • 0001652231 scopus 로고
    • The development in vitro of the blood of the early chick embryo. Proceedings of the Royal Society of London. Series B
    • Murray PDF. The development in vitro of the blood of the early chick embryo. Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character. 1932;111:497-521
    • (1932) Containing Papers of A Biological Character , vol.111 , pp. 497-521
    • Murray, P.D.F.1
  • 127
    • 0031696447 scopus 로고    scopus 로고
    • Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny
    • Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lièvre F. Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development. 1998;125:4575-4583.
    • (1998) Development , vol.125 , pp. 4575-4583
    • Jaffredo, T.1    Gautier, R.2    Eichmann, A.3    Dieterlen-Lièvre, F.4
  • 130
    • 0036714991 scopus 로고    scopus 로고
    • Blood-forming potential of vascular endothelium in the human embryo
    • Oberlin E, Tavian M, Blazsek I, Péault B. Blood-forming potential of vascular endothelium in the human embryo. Development. 2002;129:4147-4157.
    • (2002) Development , vol.129 , pp. 4147-4157
    • Oberlin, E.1    Tavian, M.2    Blazsek, I.3    Péault, B.4
  • 132
    • 0038454601 scopus 로고    scopus 로고
    • Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage
    • Sugiyama D, Ogawa M, Hirose I, Jaffredo T, Arai K, Tsuji K. Erythropoiesis from acetyl LDL incorporating endothelial cells at the preliver stage. Blood. 2003;101:4733-4738.
    • (2003) Blood , vol.101 , pp. 4733-4738
    • Sugiyama, D.1    Ogawa, M.2    Hirose, I.3    Jaffredo, T.4    Arai, K.5    Tsuji, K.6
  • 135
    • 77949895151 scopus 로고    scopus 로고
    • Haematopoietic stem cells derive directly from aortic endothelium during development
    • Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010;464:108-111.
    • (2010) Nature , vol.464 , pp. 108-111
    • Bertrand, J.Y.1    Chi, N.C.2    Santoso, B.3    Teng, S.4    Stainier, D.Y.5    Traver, D.6
  • 136
    • 77949903295 scopus 로고    scopus 로고
    • Blood stem cells emerge from aortic endothelium by a novel type of cell transition
    • Kissa K, Herbomel P. Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature. 2010;464:112-115.
    • (2010) Nature , vol.464 , pp. 112-115
    • Kissa, K.1    Herbomel, P.2
  • 138
    • 0036754045 scopus 로고    scopus 로고
    • Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population
    • Fraser ST, Ogawa M, Yu RT, Nishikawa S, Yoder MC, Nishikawa S. Definitive hematopoietic commitment within the embryonic vascular endothelial-cadherin(+) population. Exp Hematol. 2002;30:1070-1078.
    • (2002) Exp Hematol , vol.30 , pp. 1070-1078
    • Fraser, S.T.1    Ogawa, M.2    Yu, R.T.3    Nishikawa, S.4    Yoder, M.C.5    Nishikawa, S.6
  • 139
    • 54049096747 scopus 로고    scopus 로고
    • Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis
    • Goldie LC, Lucitti JL, Dickinson ME, Hirschi KK. Cell signaling directing the formation and function of hemogenic endothelium during murine embryogenesis. Blood. 2008;112:3194-3204.
    • (2008) Blood , vol.112 , pp. 3194-3204
    • Goldie, L.C.1    Lucitti, J.L.2    Dickinson, M.E.3    Hirschi, K.K.4
  • 140
    • 0141636530 scopus 로고    scopus 로고
    • Phenotype and hematopoietic potential of side population cells throughout embryonic development
    • Nadin BM, Goodell MA, Hirschi KK. Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood. 2003;102:2436-2443.
    • (2003) Blood , vol.102 , pp. 2436-2443
    • Nadin, B.M.1    Goodell, M.A.2    Hirschi, K.K.3
  • 141
    • 0029926485 scopus 로고    scopus 로고
    • Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
    • Fujiwara Y, Browne CP, Cunniff K, Goff SC, Orkin SH. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci USA. 1996;93:12355-12358.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12355-12358
    • Fujiwara, Y.1    Browne, C.P.2    Cunniff, K.3    Goff, S.C.4    Orkin, S.H.5
  • 142
    • 0036529819 scopus 로고    scopus 로고
    • Retinoid signaling regulates primitive (yolk sac) hematopoiesis
    • Ghatpande S, Ghatpande A, Sher J, Zile MH, Evans T. Retinoid signaling regulates primitive (yolk sac) hematopoiesis. Blood. 2002;99:2379-2386.
    • (2002) Blood , vol.99 , pp. 2379-2386
    • Ghatpande, S.1    Ghatpande, A.2    Sher, J.3    Zile, M.H.4    Evans, T.5
  • 143
    • 14844313685 scopus 로고    scopus 로고
    • Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation
    • Makita T, Duncan SA, Sucov HM. Retinoic acid, hypoxia, and GATA factors cooperatively control the onset of fetal liver erythropoietin expression and erythropoietic differentiation. Dev Biol. 2005;280:59-72.
    • (2005) Dev Biol , vol.280 , pp. 59-72
    • Makita, T.1    Duncan, S.A.2    Sucov, H.M.3
  • 144
    • 33646713430 scopus 로고    scopus 로고
    • RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation
    • Purton LE, Dworkin S, Olsen GH, Walkley CR, Fabb SA, Collins SJ, Chambon P. RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. J Exp Med. 2006;203:1283-1293.
    • (2006) J Exp Med , vol.203 , pp. 1283-1293
    • Purton, L.E.1    Dworkin, S.2    Olsen, G.H.3    Walkley, C.R.4    Fabb, S.A.5    Collins, S.J.6    Chambon, P.7
  • 146
    • 1342321789 scopus 로고    scopus 로고
    • Targeting c-Kit mutations: Basic science to novel therapies
    • Sattler M, Salgia R. Targeting c-Kit mutations: basic science to novel therapies. Leuk Res. 2004;28 suppl 1:S11-S20.
    • (2004) Leuk Res , vol.28 , Issue.SUPPL. 1
    • Sattler, M.1    Salgia, R.2
  • 147
    • 0023694835 scopus 로고
    • The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus
    • Chabot B, Stephenson DA, Chapman VM, Besmer P, Bernstein A. The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus. Nature. 1988;335:88-89.
    • (1988) Nature , vol.335 , pp. 88-89
    • Chabot, B.1    Stephenson, D.A.2    Chapman, V.M.3    Besmer, P.4    Bernstein, A.5
  • 151
    • 16844366556 scopus 로고    scopus 로고
    • Rbpjκ-dependent notch function regulates gata2 and is essential for the formation of intra-embryonic hematopoietic cells
    • Robert-Moreno À, Espinosa L, de la Pompa JL, Bigas A. Rbpjκ-dependent notch function regulates gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development). 2005;132:1117-1126
    • (2005) Development , vol.132 , pp. 1117-1126
    • Robert-Moreno, À.1    Espinosa, L.2    De La Pompa, J.L.3    Bigas, A.4
  • 154
    • 25844493155 scopus 로고    scopus 로고
    • Hematopoietic stem cell fate is established by the Notch-Runx pathway
    • Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005;19:2331-2342.
    • (2005) Genes Dev , vol.19 , pp. 2331-2342
    • Burns, C.E.1    Traver, D.2    Mayhall, E.3    Shepard, J.L.4    Zon, L.I.5
  • 155
    • 50849111805 scopus 로고    scopus 로고
    • Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification
    • Guo Y, Maillard I, Chakraborti S, Rothenberg EV, Speck NA. Core binding factors are necessary for natural killer cell development and cooperate with Notch signaling during T-cell specification. Blood. 2008;112:480-492.
    • (2008) Blood , vol.112 , pp. 480-492
    • Guo, Y.1    Maillard, I.2    Chakraborti, S.3    Rothenberg, E.V.4    Speck, N.A.5
  • 156
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
    • Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci USA. 1996;93:3444-3449.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Binder, M.3    Marin-Padilla, M.4    Sharpe, A.H.5    Speck, N.A.6
  • 158
    • 30144434921 scopus 로고    scopus 로고
    • Runx1 function in hematopoiesis is required in cells that express Tek
    • Li Z, Chen MJ, Stacy T, Speck NA. Runx1 function in hematopoiesis is required in cells that express Tek. Blood. 2006;107:106-110.
    • (2006) Blood , vol.107 , pp. 106-110
    • Li, Z.1    Chen, M.J.2    Stacy, T.3    Speck, N.A.4
  • 159
    • 60149100010 scopus 로고    scopus 로고
    • Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
    • Chen MJ, Yokomizo T, Zeigler BM, Dzierzak E, Speck NA. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature. 2009;457:887-891.
    • (2009) Nature , vol.457 , pp. 887-891
    • Chen, M.J.1    Yokomizo, T.2    Zeigler, B.M.3    Dzierzak, E.4    Speck, N.A.5
  • 160
    • 24744439953 scopus 로고    scopus 로고
    • Involvement of Runx1 in the down-regulation of fetal liver kinase-1
    • Hirai H, Samokhvalov IM, Fujimoto T, Nishikawa S, Imanishi J, Nishikawa S. Involvement of Runx1 in the down-regulation of fetal liver kinase-1 expression during transition of endothelial cells to hematopoietic cells. Blood. 2005;106:1948-1955.
    • (2005) Blood , vol.106 , pp. 1948-1955
    • Hirai, H.1    Samokhvalov, I.M.2    Fujimoto, T.3    Nishikawa, S.4    Imanishi, J.5    Nishikawa, S.6
  • 161
    • 0037305236 scopus 로고    scopus 로고
    • Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis
    • Hirai H, Ogawa M, Suzuki N, Yamamoto M, Breier G, Mazda O, Imanishi J, Nishikawa S. Hemogenic and nonhemogenic endothelium can be distinguished by the activity of fetal liver kinase (Flk)-1 promoter/enhancer during mouse embryogenesis. Blood. 2003;101:886-893.
    • (2003) Blood , vol.101 , pp. 886-893
    • Hirai, H.1    Ogawa, M.2    Suzuki, N.3    Yamamoto, M.4    Breier, G.5    Mazda, O.6    Imanishi, J.7    Nishikawa, S.8
  • 162
    • 84861223149 scopus 로고    scopus 로고
    • The transcriptional programme controlled by Runx1 during early embryonic blood development
    • Tanaka Y, Joshi A, Wilson NK, Kinston S, Nishikawa S, Göttgens B. The transcriptional programme controlled by Runx1 during early embryonic blood development. Dev Biol. 2012;366:404-419.
    • (2012) Dev Biol , vol.366 , pp. 404-419
    • Tanaka, Y.1    Joshi, A.2    Wilson, N.K.3    Kinston, S.4    Nishikawa, S.5    Göttgens, B.6
  • 163
    • 79955883317 scopus 로고    scopus 로고
    • Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators
    • Tijssen MR, Cvejic A, Joshi A, et al. Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators. Dev Cell. 2011;20:597-609.
    • (2011) Dev Cell , vol.20 , pp. 597-609
    • Tijssen, M.R.1    Cvejic, A.2    Joshi, A.3
  • 165
    • 0028278325 scopus 로고
    • The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development
    • Warren AJ, Colledge WH, Carlton MB, Evans MJ, Smith AJ, Rabbitts TH. The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development. Cell. 1994;78:45-57.
    • (1994) Cell , vol.78 , pp. 45-57
    • Warren, A.J.1    Colledge, W.H.2    Carlton, M.B.3    Evans, M.J.4    Smith, A.J.5    Rabbitts, T.H.6
  • 167
    • 0025977563 scopus 로고
    • Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
    • Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Costantini F. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature. 1991;349:257-260.
    • (1991) Nature , vol.349 , pp. 257-260
    • Pevny, L.1    Simon, M.C.2    Robertson, E.3    Klein, W.H.4    Tsai, S.F.5    D'Agati, V.6    Orkin, S.H.7    Costantini, F.8
  • 168
    • 33947223259 scopus 로고    scopus 로고
    • The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish
    • Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, Patient R. The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish. Blood. 2007;109:2389-2398.
    • (2007) Blood , vol.109 , pp. 2389-2398
    • Patterson, L.J.1    Gering, M.2    Eckfeldt, C.E.3    Green, A.R.4    Verfaillie, C.M.5    Ekker, S.C.6    Patient, R.7
  • 169
    • 18244392936 scopus 로고    scopus 로고
    • Scl is required for dorsal aorta as well as blood formation in zebrafish embryos
    • Patterson LJ, Gering M, Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood. 2005;105:3502-3511.
    • (2005) Blood , vol.105 , pp. 3502-3511
    • Patterson, L.J.1    Gering, M.2    Patient, R.3
  • 170
    • 0034602651 scopus 로고    scopus 로고
    • The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice
    • Yamada Y, Pannell R, Forster A, Rabbitts TH. The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice. Proc Natl Acad Sci USA. 2000;97:320-324.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 320-324
    • Yamada, Y.1    Pannell, R.2    Forster, A.3    Rabbitts, T.H.4
  • 172
    • 0033485333 scopus 로고    scopus 로고
    • SCL expression in the mouse embryo detected with a targeted lacZ reporter gene demonstrates its localization to hematopoietic, vascular, and neural tissues
    • Elefanty AG, Begley CG, Hartley L, Papaevangeliou B, Robb L. SCL expression in the mouse embryo detected with a targeted lacZ reporter gene demonstrates its localization to hematopoietic, vascular, and neural tissues. Blood. 1999;94:3754-3763.
    • (1999) Blood , vol.94 , pp. 3754-3763
    • Elefanty, A.G.1    Begley, C.G.2    Hartley, L.3    Papaevangeliou, B.4    Robb, L.5
  • 173
    • 18544364934 scopus 로고    scopus 로고
    • Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development
    • Schlaeger TM, Mikkola HK, Gekas C, Helgadottir HB, Orkin SH. Tie2Cre-mediated gene ablation defines the stem-cell leukemia gene (SCL/tal1)-dependent window during hematopoietic stem-cell development. Blood. 2005;105:3871-3874.
    • (2005) Blood , vol.105 , pp. 3871-3874
    • Schlaeger, T.M.1    Mikkola, H.K.2    Gekas, C.3    Helgadottir, H.B.4    Orkin, S.H.5
  • 174
    • 0030581174 scopus 로고    scopus 로고
    • The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages
    • Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages. Cell. 1996;86:47-57.
    • (1996) Cell , vol.86 , pp. 47-57
    • Porcher, C.1    Swat, W.2    Rockwell, K.3    Fujiwara, Y.4    Alt, F.W.5    Orkin, S.H.6
  • 175
    • 0037472895 scopus 로고    scopus 로고
    • Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene
    • Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y, Orkin SH. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature. 2003;421:547-551.
    • (2003) Nature , vol.421 , pp. 547-551
    • Mikkola, H.K.1    Klintman, J.2    Yang, H.3    Hock, H.4    Schlaeger, T.M.5    Fujiwara, Y.6    Orkin, S.H.7
  • 176
    • 0038618957 scopus 로고    scopus 로고
    • From mesoderm to blood islands: Patterns of key molecules during yolk sac erythropoiesis
    • Minko K, Bollerot K, Drevon C, Hallais MF, Jaffredo T. From mesoderm to blood islands: patterns of key molecules during yolk sac erythropoiesis. Gene Expr Patterns. 2003;3:261-272.
    • (2003) Gene Expr Patterns , vol.3 , pp. 261-272
    • Minko, K.1    Bollerot, K.2    Drevon, C.3    Hallais, M.F.4    Jaffredo, T.5
  • 177
    • 0041806587 scopus 로고    scopus 로고
    • GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling
    • Grass JA, Boyer ME, Pal S, Wu J, Weiss MJ, Bresnick EH. GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. Proc Natl Acad Sci USA. 2003;100:8811-8816.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8811-8816
    • Grass, J.A.1    Boyer, M.E.2    Pal, S.3    Wu, J.4    Weiss, M.J.5    Bresnick, E.H.6
  • 178
    • 0034932701 scopus 로고    scopus 로고
    • Primitive erythropoiesis in the Xenopus embryo: The synergistic role of LMO-2 SCL and GATA-binding proteins
    • Mead PE, Deconinck AE, Huber TL, Orkin SH, Zon LI. Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. Development. 2001;128:2301-2308.
    • (2001) Development , vol.128 , pp. 2301-2308
    • Mead, P.E.1    Deconinck, A.E.2    Huber, T.L.3    Orkin, S.H.4    Zon, L.I.5
  • 180
    • 76049120037 scopus 로고    scopus 로고
    • Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation
    • Lieu YK, Reddy EP. Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation. Proc Natl Acad Sci USA. 2009;106:21689-21694.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 21689-21694
    • Lieu, Y.K.1    Reddy, E.P.2
  • 181
    • 78049236939 scopus 로고    scopus 로고
    • Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved
    • Soza-Ried C, Hess I, Netuschil N, Schorpp M, Boehm T. Essential role of c-myb in definitive hematopoiesis is evolutionarily conserved. Proc Natl Acad Sci USA. 2010;107:17304-17308.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17304-17308
    • Soza-Ried, C.1    Hess, I.2    Netuschil, N.3    Schorpp, M.4    Boehm, T.5
  • 183
    • 0026036051 scopus 로고
    • Constitutive expression of exogenous c-myb gene causes maturation block in monocyte-macrophage differentiation
    • Yanagisawa H, Nagasawa T, Kuramochi S, Abe T, Ikawa Y, Todokoro K. Constitutive expression of exogenous c-myb gene causes maturation block in monocyte-macrophage differentiation. Biochim Biophys Acta. 1991;1088:380-384.
    • (1991) Biochim Biophys Acta , vol.1088 , pp. 380-384
    • Yanagisawa, H.1    Nagasawa, T.2    Kuramochi, S.3    Abe, T.4    Ikawa, Y.5    Todokoro, K.6
  • 184
    • 23444452042 scopus 로고    scopus 로고
    • Molecular basis of the effects of shear stress on vascular endothelial cells
    • Li YS, Haga JH, Chien S. Molecular basis of the effects of shear stress on vascular endothelial cells. J Biomech. 2005;38:1949-1971.
    • (2005) J Biomech , vol.38 , pp. 1949-1971
    • Li, Y.S.1    Haga, J.H.2    Chien, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.