메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages

Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients

Author keywords

[No Author keywords available]

Indexed keywords

BETA4 INTEGRIN; FOCAL ADHESION KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MONOCARBOXYLATE TRANSPORTER 4; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SMALL INTERFERING RNA;

EID: 84900462660     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0087904     Document Type: Article
Times cited : (56)

References (45)
  • 2
    • 0033024542 scopus 로고    scopus 로고
    • Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection
    • DOI 10.1016/S1368-8375(98)00113-4, PII S1368837598001134
    • Woolgar JA, Rogers S, West CR, Errington RD, Brown JS, et al. (1999) Survival and patterns of recurrence in 200 oral cancer patients treated by radical surgery and neck dissection. Oral Oncol 35: 257-265. (Pubitemid 29148358)
    • (1999) Oral Oncology , vol.35 , Issue.3 , pp. 257-265
    • Woolgar, J.A.1    Rogers, S.2    West, C.R.3    Errington, R.D.4    Brown, J.S.5    Vaughan, E.D.6
  • 3
    • 80051580618 scopus 로고    scopus 로고
    • Cancer statistics, 2011: The impact of eliminating socioeconomic and racial disparities on premature cancer deaths
    • Siegel R, Ward E, Brawley O, Jemal A (2011) Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin 61: 212-236.
    • (2011) CA Cancer J Clin , vol.61 , pp. 212-236
    • Siegel, R.1    Ward, E.2    Brawley, O.3    Jemal, A.4
  • 6
    • 84864487873 scopus 로고    scopus 로고
    • Delineating metabolic signatures of head and neck squamous cell carcinoma: Phospholipase A2, a potential therapeutic target
    • Tripathi P, Kamarajan P, Somashekar BS, MacKinnon N, Chinnaiyan AM, et al. (2012) Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target. Int J Biochem Cell Biol 44: 1852-1861.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 1852-1861
    • Tripathi, P.1    Kamarajan, P.2    Somashekar, B.S.3    MacKinnon, N.4    Chinnaiyan, A.M.5
  • 7
    • 83755207529 scopus 로고    scopus 로고
    • Defining the molecular basis of tumor metabolism: A continuing challenge since Warburg's discovery
    • de Souza AC, Justo GZ, de Araujo DR, Cavagis AD (2011) Defining the molecular basis of tumor metabolism: a continuing challenge since Warburg's discovery. Cell Physiol Biochem 28: 771-792.
    • (2011) Cell Physiol Biochem , vol.28 , pp. 771-792
    • De Souza, A.C.1    Justo, G.Z.2    De Araujo, D.R.3    Cavagis, A.D.4
  • 9
    • 79954603194 scopus 로고    scopus 로고
    • Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells
    • Izumi H, Takahashi M, Uramoto H, Nakayama Y, Oyama T, et al. (2011) Monocarboxylate transporters 1 and 4 are involved in the invasion activity of human lung cancer cells. Cancer Sci 102: 1007-1013.
    • (2011) Cancer Sci , vol.102 , pp. 1007-1013
    • Izumi, H.1    Takahashi, M.2    Uramoto, H.3    Nakayama, Y.4    Oyama, T.5
  • 10
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Broer S (2000) The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 350 Pt 1: 219-227.
    • (2000) Biochem J , vol.350 , Issue.PART 1 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Broer, S.5
  • 11
    • 0035717984 scopus 로고    scopus 로고
    • Metabolic mapping with bioluminescence: Basic and clinical relevance
    • DOI 10.1016/S1389-0344(01)00107-1, PII S1389034401001071
    • Walenta S, Schroeder T, Mueller-Klieser W (2002) Metabolic mapping with bioluminescence: basic and clinical relevance. Biomol Eng 18: 249-262. (Pubitemid 34158559)
    • (2002) Biomolecular Engineering , vol.18 , Issue.6 , pp. 249-262
    • Walenta, S.1    Schroeder, T.2    Mueller-Klieser, W.3
  • 12
    • 0036347515 scopus 로고    scopus 로고
    • Lactate stimulates fibroblast expression of hyaluronan and CD44: The Warburg effect revisited
    • DOI 10.1006/excr.2002.5508
    • Stern R, Shuster S, Neudecker BA, Formby B (2002) Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited. Exp Cell Res 276: 24-31. (Pubitemid 34948348)
    • (2002) Experimental Cell Research , vol.276 , Issue.1 , pp. 24-31
    • Stern, R.1    Shuster, S.2    Neudecker, B.A.3    Formby, B.4
  • 13
    • 33745535252 scopus 로고    scopus 로고
    • Tumor microenvironment modulates hyaluronan expression: The lactate effect
    • DOI 10.1038/sj.jid.5700255, PII 5700255
    • Rudrabhatla SR, Mahaffey CL, Mummert ME (2006) Tumor microenvironment modulates hyaluronan expression: the lactate effect. J Invest Dermatol 126: 1378-1387. (Pubitemid 43997922)
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.6 , pp. 1378-1387
    • Rudrabhatla, S.R.1    Mahaffey, C.L.2    Mummert, M.E.3
  • 14
    • 57449097020 scopus 로고    scopus 로고
    • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    • Sonveaux P, Vegran F, Schroeder T, Wergin MC, Verrax J, et al. (2008) Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest 118: 3930-3942.
    • (2008) J Clin Invest , vol.118 , pp. 3930-3942
    • Sonveaux, P.1    Vegran, F.2    Schroeder, T.3    Wergin, M.C.4    Verrax, J.5
  • 15
    • 0030933001 scopus 로고    scopus 로고
    • Lactate-proton cotransport in skeletal muscle
    • Juel C (1997) Lactate-proton cotransport in skeletal muscle. Physiol Rev 77: 321-358.
    • (1997) Physiol Rev , vol.77 , pp. 321-358
    • Juel, C.1
  • 17
    • 34249293335 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
    • DOI 10.1158/0008-5472.CAN-06-3184
    • Gallagher SM, Castorino JJ, Wang D, Philp NJ (2007) Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231. Cancer Res 67: 4182-4189. (Pubitemid 46815064)
    • (2007) Cancer Research , vol.67 , Issue.9 , pp. 4182-4189
    • Gallagher, S.M.1    Castorino, J.J.2    Wang, D.3    Philp, N.J.4
  • 18
    • 84855370259 scopus 로고    scopus 로고
    • Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer
    • Nakayama Y, Torigoe T, Inoue Y, Minagawa N, Izumi H, et al. (2012) Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer. Exp Ther Med 3: 25-30.
    • (2012) Exp Ther Med , vol.3 , pp. 25-30
    • Nakayama, Y.1    Torigoe, T.2    Inoue, Y.3    Minagawa, N.4    Izumi, H.5
  • 19
    • 79960587072 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer
    • Pertega-Gomes N, Vizcaino JR, Miranda-Goncalves V, Pinheiro C, Silva J, et al. (2011) Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer. BMC Cancer 11: 312.
    • (2011) BMC Cancer , vol.11 , pp. 312
    • Pertega-Gomes, N.1    Vizcaino, J.R.2    Miranda-Goncalves, V.3    Pinheiro, C.4    Silva, J.5
  • 20
    • 84860655854 scopus 로고    scopus 로고
    • Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target
    • Gerlinger M, Santos CR, Spencer-Dene B, Martinez P, Endesfelder D, et al. (2012) Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. J Pathol 227: 146-156.
    • (2012) J Pathol , vol.227 , pp. 146-156
    • Gerlinger, M.1    Santos, C.R.2    Spencer-Dene, B.3    Martinez, P.4    Endesfelder, D.5
  • 21
    • 0028947575 scopus 로고
    • Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies
    • Cardinali M, Pietraszkiewicz H, Ensley JF, Robbins KC (1995) Tyrosine phosphorylation as a marker for aberrantly regulated growth-promoting pathways in cell lines derived from head and neck malignancies. Int J Cancer 61: 98-103.
    • (1995) Int J Cancer , vol.61 , pp. 98-103
    • Cardinali, M.1    Pietraszkiewicz, H.2    Ensley, J.F.3    Robbins, K.C.4
  • 22
    • 0033755157 scopus 로고    scopus 로고
    • Neutron radiation enhances cisplatin cytotoxicity independently of apoptosis in human head and neck carcinoma cells
    • Kim HE, Krug MA, Han I, Ensley J, Yoo GH, et al. (2000) Neutron radiation enhances cisplatin cytotoxicity independently of apoptosis in human head and neck carcinoma cells. Clin Cancer Res 6: 4142-4147.
    • (2000) Clin Cancer Res , vol.6 , pp. 4142-4147
    • Kim, H.E.1    Krug, M.A.2    Han, I.3    Ensley, J.4    Yoo, G.H.5
  • 23
    • 18844407070 scopus 로고    scopus 로고
    • Profiling EGFR activity in head and neck squamous cell carcinoma by using a novel layered membrane Western blot technology
    • DOI 10.1016/j.oraloncology.2004.12.010, PII S1368837505000242
    • Patel V, Ramesh A, Traicoff JL, Baibakov G, Emmert-Buck MR, et al. (2005) Profiling EGFR activity in head and neck squamous cell carcinoma by using a novel layered membrane Western blot technology. Oral Oncol 41: 503-508. (Pubitemid 40692851)
    • (2005) Oral Oncology , vol.41 , Issue.5 , pp. 503-508
    • Patel, V.1    Ramesh, A.2    Traicoff, J.L.3    Baibakov, G.4    Emmert-Buck, M.R.5    Gutkind, J.S.6    Knezevic, V.7
  • 24
    • 0036048217 scopus 로고    scopus 로고
    • Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling
    • Avizienyte E, Wyke AW, Jones RJ, McLean GW, Westhoff MA, et al. (2002) Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling. Nat Cell Biol 4: 632-638.
    • (2002) Nat Cell Biol , vol.4 , pp. 632-638
    • Avizienyte, E.1    Wyke, A.W.2    Jones, R.J.3    McLean, G.W.4    Westhoff, M.A.5
  • 25
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 26
    • 0034663601 scopus 로고    scopus 로고
    • The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells
    • Dimmer KS, Friedrich B, Lang F, Deitmer JW, Broer S (2000) The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells. Biochem J 350 Pt 1: 219-227.
    • (2000) Biochem J , vol.350 , Issue.PART 1 , pp. 219-227
    • Dimmer, K.S.1    Friedrich, B.2    Lang, F.3    Deitmer, J.W.4    Broer, S.5
  • 27
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • DOI 10.1038/nrc1478
    • Gatenby RA, Gillies RJ (2004) Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899. (Pubitemid 39472955)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 28
    • 35448940364 scopus 로고    scopus 로고
    • Adaptive landscapes and emergent phenotypes: Why do cancers have high glycolysis?
    • DOI 10.1007/s10863-007-9085-y, Special Topic: The Warburg Effect: Its Continued Impact on Cancer Research into the 21st Century
    • Gillies RJ, Gatenby RA (2007) Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? J Bioenerg Biomembr 39: 251-257. (Pubitemid 47619378)
    • (2007) Journal of Bioenergetics and Biomembranes , vol.39 , Issue.3 , pp. 251-257
    • Gillies, R.J.1    Gatenby, R.A.2
  • 29
  • 30
    • 65249168811 scopus 로고    scopus 로고
    • Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration
    • Gallagher SM, Castorino JJ, Philp NJ (2009) Interaction of monocarboxylate transporter 4 with beta1-integrin and its role in cell migration. Am J Physiol Cell Physiol 296: C414-C421.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Gallagher, S.M.1    Castorino, J.J.2    Philp, N.J.3
  • 31
    • 69949124867 scopus 로고    scopus 로고
    • Pyruvate into lactate and back: From the Warburg effect to symbiotic energy fuel exchange in cancer cells
    • Feron O (2009) Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiother Oncol 92: 329-333.
    • (2009) Radiother Oncol , vol.92 , pp. 329-333
    • Feron, O.1
  • 32
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes RO (1992) Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69: 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.O.1
  • 33
    • 84879414971 scopus 로고    scopus 로고
    • Integrin beta5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways
    • Bianchi-Smiraglia A, Paesante S, Bakin AV (2013) Integrin beta5 contributes to the tumorigenic potential of breast cancer cells through the Src-FAK and MEK-ERK signaling pathways. Oncogene 32: 3049-3058.
    • (2013) Oncogene , vol.32 , pp. 3049-3058
    • Bianchi-Smiraglia, A.1    Paesante, S.2    Bakin, A.V.3
  • 34
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier JS, Cheresh DA (2010) Integrins in cancer: biological implications and therapeutic opportunities. Nat Rev Cancer 10: 9-22.
    • (2010) Nat Rev Cancer , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 35
    • 77953550880 scopus 로고    scopus 로고
    • Role of beta5-integrin in epithelial-mesenchymal transition in response to TGF-beta
    • Bianchi A, Gervasi ME, Bakin A (2010) Role of beta5-integrin in epithelial-mesenchymal transition in response to TGF-beta. Cell Cycle 9: 1647-1659.
    • (2010) Cell Cycle , vol.9 , pp. 1647-1659
    • Bianchi, A.1    Gervasi, M.E.2    Bakin, A.3
  • 38
    • 13944282937 scopus 로고    scopus 로고
    • Identification of Src-specific phosphorylation site on focal adhesion kinase: Dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
    • DOI 10.1158/0008-5472.CAN-04-1949
    • Brunton VG, Avizienyte E, Fincham VJ, Serrels B, Metcalf CR, et al. (2005) Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior. Cancer Res 65: 1335-1342. (Pubitemid 40270160)
    • (2005) Cancer Research , vol.65 , Issue.4 , pp. 1335-1342
    • Brunton, V.G.1    Avizienyte, E.2    Fincham, V.J.3    Serrels, B.4    Metcalf III, C.A.5    Sawyer, T.K.6    Frame, M.C.7
  • 39
    • 0033772308 scopus 로고    scopus 로고
    • FAK integrates growth-factor and integrin signals to promote cell migration
    • Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, et al. (2000) FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol 2: 249-256.
    • (2000) Nat Cell Biol , vol.2 , pp. 249-256
    • Sieg, D.J.1    Hauck, C.R.2    Ilic, D.3    Klingbeil, C.K.4    Schaefer, E.5
  • 40
    • 0030874021 scopus 로고    scopus 로고
    • Integrin-mediated activation of MAP kinase is independent of FAK: Evidence for dual integrin signaling pathways in fibroblasts
    • DOI 10.1083/jcb.136.6.1385
    • Lin TH, Aplin AE, Shen Y, Chen Q, Schaller M, et al. (1997) Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts. J Cell Biol 136: 1385-1395. (Pubitemid 27421923)
    • (1997) Journal of Cell Biology , vol.136 , Issue.6 , pp. 1385-1395
    • Lin, T.H.1    Aplin, A.E.2    Shen, Y.3    Chen, Q.4    Schaller, M.5    Romer, L.6    Aukhil, I.7    Juliano, R.L.8
  • 41
    • 0031921101 scopus 로고    scopus 로고
    • Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: Summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events?
    • Schlaepfer DD, Jones KC, Hunter T (1998) Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events. Mol Cell Biol 18: 2571-2585. (Pubitemid 28183427)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.5 , pp. 2571-2585
    • Schlaepfer, D.D.1    Jones, K.C.2    Hunter, T.3
  • 42
    • 0028609382 scopus 로고
    • Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase
    • Schlaepfer DD, Hanks SK, Hunter T, van der Geer P (1994) Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372: 786-791.
    • (1994) Nature , vol.372 , pp. 786-791
    • Schlaepfer, D.D.1    Hanks, S.K.2    Hunter, T.3    Van Der Geer, P.4
  • 45
    • 0031830664 scopus 로고    scopus 로고
    • Inactivation of the E-cadherin-mediated cell adhesion system in human cancers
    • Hirohashi S (1998) Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153: 333-339.
    • (1998) Am J Pathol , vol.153 , pp. 333-339
    • Hirohashi, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.