Optogenetic manipulation of activity and temporally controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation

Journal of Neuroscience

Volumn 34, Issue 20, 2014, Pages 6896-6909

  Tsunematsu, Tomomi ^a,b   Ueno, Takafumi ^c   Tabuchi, Sawako ^a,b,d   Inutsuka, Ayumu ^a   Tanaka, Kenji F ^e   Hasuwa, Hidetoshi ^f   Kilduff, Thomas S ^g   Terao, Akira ^c   Yamanaka, Akihiro ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^e KEIO UNIVERSITY   (Japan)

^f OSAKA UNIVERSITY   (Japan)

^g SRI INTERNATIONAL   (United States)

Author keywords

Ablation; Cell fate; Channelrhodopsin2; Hypothalamus; Optogenetics; REM sleep

Indexed keywords

MELANIN CONCENTRATING HORMONE; OREXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTROENCEPHALOGRAPHY; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; OPTOGENETICS; POLYSOMNOGRAPHY; PRIORITY JOURNAL; REM SLEEP; SLEEP WAKING CYCLE; SOUTHERN BLOTTING; TRANSGENIC MOUSE; WAKEFULNESS;

ABLATION; CELL FATE; CHANNELRHODOPSIN2; HYPOTHALAMUS; OPTOGENETICS; REM SLEEP;

ANIMALS; HYPOTHALAMIC HORMONES; MELANINS; MICE; MICE, TRANSGENIC; NEURONS; OPTOGENETICS; PITUITARY HORMONES; SLEEP; WAKEFULNESS;

EID: 84900442115     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5344-13.2014     Document Type: Article

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