Long-lasting silencing of orexin/hypocretin neurons using archaerhodopsin induces slow-wave sleep in mice

Behavioural Brain Research

Volumn 255, Issue , 2013, Pages 64-74

  Tsunematsu, Tomomi ^a,b   Tabuchi, Sawako ^a,b,c   Tanaka, Kenji F ^d   Boyden, Edward S ^e   Tominaga, Makoto ^a,c   Yamanaka, Akihiro ^a,f,g  

^a OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^c GRADUATE UNIVERSITY FOR ADVANCED STUDIES   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e Massachusetts Institute of Technology Cambridge   (United States)

^f NAGOYA UNIVERSITY   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Archaerhodopsin; Hypocretin; Optogenetic; Orexin; Slow wave sleep

Indexed keywords

ARCHAERHODOPSIN; OREXIN 2 RECEPTOR; PROTEIN C FOS; RHODOPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SLICE; CELL ACTIVITY; CONTROLLED STUDY; FEMALE; GENE; HALORUBRUM; ILLUMINATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MOUSE; NERVE CELL; NONHUMAN; OREXIN NEURON; PATCH CLAMP; PREPRO OREXIN GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SLOW WAVE SLEEP; TRANSGENIC MOUSE; WAKEFULNESS;

ARCHAERHODOPSIN; HYPOCRETIN; OPTOGENETIC; OREXIN; SLOW-WAVE SLEEP;

ANIMALS; ARCHAEAL PROTEINS; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, TRANSGENIC; NEURAL INHIBITION; NEURONS; NEUROPEPTIDES; OPTOGENETICS; SLEEP; SLEEP STAGES;

EID: 84884979110     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.05.021     Document Type: Article

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