An high-throughput in vivo screening system to select H3K4-specific histone demethylase inhibitors

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Mannironi, Cecilia ^a   Proietto, Marco ^b   Bufalieri, Francesca ^b   Cundari, Enrico ^a   Alagia, Angela ^b   Danovska, Svetlana ^b   Rinaldi, Teresa ^b   Famiglini, Valeria ^b   Coluccia, Antonio ^b   La Regina, Giuseppe ^b   Silvestri, Romano ^b   Negri, Rodolfo ^b  

^a CNR   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPOUND 3195; HISTONE DEMETHYLASE INHIBITOR; HISTONE H3; OXYGENASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOSTASIS; DEMETHYLATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG SCREENING; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; FUNGUS GROWTH; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; SACCHAROMYCES CEREVISIAE;

COENZYMES; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; KETOGLUTARIC ACIDS; METHYLATION; SACCHAROMYCES CEREVISIAE; SIROLIMUS; SMALL MOLECULE LIBRARIES;

EID: 84900435770     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086002     Document Type: Article

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