Contextualised urinary biomarker analysis facilitates diagnosis of paediatric obstructive sleep apnoea

Sleep Medicine

Volumn 15, Issue 5, 2014, Pages 541-549

  Becker, Lev ^a   Kheirandish Gozal, Leila ^a   Peris, Eduard ^a   Schoenfelt, Kelly Q ^a   Gozal, David ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Biomarkers; Diagnosis; Gender; Obstructive sleep apnoea; Paediatric; Urine proteomics

Indexed keywords

BIOLOGICAL MARKER; PROTEIN; PEPTIDE;

ARTICLE; CHILD; CIRCADIAN RHYTHM; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENDER; HUMAN; HYPERCAPNIA; HYPOXIA; LIQUID CHROMATOGRAPHY; MALE; PRIORITY JOURNAL; PROTEOMICS; SLEEP DISORDERED BREATHING; SLEEP QUALITY; TANDEM MASS SPECTROMETRY; URINALYSIS; CASE CONTROL STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; POLYSOMNOGRAPHY; PRESCHOOL CHILD; PROTEINURIA; SEX DIFFERENCE; SLEEP APNEA, OBSTRUCTIVE; URINE;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; CIRCADIAN RHYTHM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; PEPTIDES; POLYSOMNOGRAPHY; PROTEINURIA; PROTEOMICS; SEX FACTORS; SLEEP APNEA, OBSTRUCTIVE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84900022747     PISSN: 13899457     EISSN: 18785506     Source Type: Journal    
DOI: 10.1016/j.sleep.2014.01.010     Document Type: Article

References (45)

1. Gozal D., Capdevila O.S., Kheirandish-Gozal L. Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children. Am J Respir Crit Care Med 2008, 177(10):1142-1149. [Epub 2008/02/16].
2. Gozal D., Kheirandish-Gozal L. Cardiovascular morbidity in obstructive sleep apnea: oxidative stress, inflammation, and much more. Am J Respir Crit Care Med 2008, 177(4):369-375. [Epub 2007/11/03].
3. Gozal D., Kheirandish-Gozal L. The multiple challenges of obstructive sleep apnea in children: morbidity and treatment. Curr Opin Pediatr 2008, 20(6):654-658. [Epub 2008/11/14].
4. Gozal D., Kheirandish-Gozal L. Childhood obesity and sleep: relatives, partners, or both? - a critical perspective on the evidence. Ann NY Acad Sci 2012, 1264(1):135-141. [Epub 2012/08/14].
5. Gozal D., Kheirandish-Gozal L., Bhattacharjee R., Spruyt K. Neurocognitive and endothelial dysfunction in children with obstructive sleep apnea. Pediatrics 2010, 126(5):e1161-7. Epub 2010/10/20.
6. Kim J., Hakim F., Kheirandish-Gozal L., Gozal D. Inflammatory pathways in children with insufficient or disordered sleep. Respir Physiol Neurobiol 2011, 178(3):465-474. [Epub 2011/05/17].
7. Soggiu A., Piras C., Bonizzi L., Hussein H.A., Pisanu S., Roncada P. A discovery-phase urine proteomics investigation in type 1 diabetes. Acta Diabetol 2012, [Epub 2012/06/09].
8. Zimmerli L.U., Schiffer E., Zurbig P., Good D.M., Kellmann M., Mouls L., et al. Urinary proteomic biomarkers in coronary artery disease. Mol Cell Proteomics 2008, 7(2):290-298. [Epub 2007/10/24].
9. Riaz S., Alam S.S., Srai S.K., Skinner V., Riaz A., Akhtar M.W. Proteomic identification of human urinary biomarkers in diabetes mellitus type 2. Diabetes Technol Ther 2010, 12(12):979-988. [Epub 2010/08/26].
10. Zengi O., Karakas A., Ergun U., Senes M., Inan L., Yucel D. Urinary 8-hydroxy-2'-deoxyguanosine level and plasma paraoxonase 1 activity with Alzheimer's disease. Clin Chem Lab Med 2012, 50(3):529-534. [Epub 2011/11/22].
11. Huttenhain R., Soste M., Selevsek N., Rost H., Sethi A., Carapito C., et al. Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics. Sci Transl Med 2012, 4(142):142ra94. [Epub 2012/07/13].
12. Zoidakis J., Makridakis M., Zerefos P.G., Bitsika V., Esteban S., Frantzi M., et al. Profilin 1 is a potential biomarker for bladder cancer aggressiveness. Mol Cell Proteomics 2012, 11(4). [M111 009449 Epub 2011/12/14].
13. Zurbig P., Jerums G., Hovind P., Macisaac R., Mischak H., Nielsen S.E., et al. Urinary proteomics for early diagnosis in diabetic nephropathy. Diabetes 2012, [Epub 2012/08/09].
14. Siwy J., Mullen W., Golovko I., Franke J., Zurbig P. Human urinary peptide database for multiple disease biomarker discovery. Proteomics Clin Appl 2011, 5(5-6):367-374. [Epub 2011/05/19].
15. Gozal D., Jortani S., Snow A.B., Kheirandish-Gozal L., Bhattacharjee R., Kim J., et al. Two-dimensional differential in-gel electrophoresis proteomic approaches reveal urine candidate biomarkers in pediatric obstructive sleep apnea. Am J Respir Crit Care Med 2009, 180(12):1253-1261. [Epub 2009/10/03].
16. Kentsis A. Challenges and opportunities for discovery of disease biomarkers using urine proteomics. Pediatr Int 2011, 53(1):1-6. [Epub 2010/09/16].
17. Montgomery-Downs H.E., O'Brien L.M., Gulliver T.E., Gozal D. Polysomnographic characteristics in normal preschool and early school-aged children. Pediatrics 2006, 117(3):741-753. [Epub 2006/03/03].
18. C. Iber SA-I, A. Chesson, S. Quan, for the American Academy of Sleep Medicine. The AASM manual for the scoring of sleep and associated events: rules, terminology, and technical specifications. 2007.
19. Becker L., Gharib S.A., Irwin A.D., Wijsman E., Vaisar T., Oram J.F., et al. A macrophage sterol-responsive network linked to atherogenesis. Cell Metab 2010, 11(2):125-135. [Epub 2010/02/10].
20. Thongboonkerd V., Chutipongtanate S., Kanlaya R. Systematic evaluation of sample preparation methods for gel-based human urinary proteomics: quantity, quality, and variability. J Proteome Res 2006, 5(1):183-191. [Epub 2006/01/07].
21. Kersey P.J., Duarte J., Williams A., Karavidopoulou Y., Birney E., Apweiler R. The International Protein Index: an integrated database for proteomics experiments. Proteomics 2004, 4(7):1985-1988. [Epub 2004/06/29].
22. Keller A., Nesvizhskii A.I., Kolker E., Aebersold R. Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search. Anal Chem 2002, 74(20):5383-5392. [Epub 2002/10/31].
23. Nesvizhskii A.I., Keller A., Kolker E., Aebersold R. A statistical model for identifying proteins by tandem mass spectrometry. Anal Chem 2003, 75(17):4646-4658. [Epub 2003/11/25].
24. Rauch A., Bellew M., Eng J., Fitzgibbon M., Holzman T., Hussey P., et al. Computational Proteomics Analysis System (CPAS): an extensible, open-source analytic system for evaluating and publishing proteomic data and high throughput biological experiments. J Proteome Res 2006, 5(1):112-121. [Epub 2006/01/07].
25. Liu H., Sadygov R.G., Yates J.R. A model for random sampling and estimation of relative protein abundance in shotgun proteomics. Anal Chem 2004, 76(14):4193-4201. [Epub 2004/07/16].
26. Becker L., Liu N.C., Averill M.M., Yuan W., Pamir N., Peng Y., et al. Unique proteomic signatures distinguish macrophages and dendritic cells. PLoS One 2012, 7(3):e33297. [Epub 2012/03/20].
27. Old W.M., Meyer-Arendt K., Aveline-Wolf L., Pierce K.G., Mendoza A., Sevinsky J.R., et al. Comparison of label-free methods for quantifying human proteins by shotgun proteomics. Mol Cell Proteomics 2005, 4(10):1487-1502. [Epub 2005/06/28].
28. Benjamini Y., Hochberg Y. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J Roy Stat Soc B Met 1995, 57(1):289-300.
29. Heinecke N.L., Pratt B.S., Vaisar T., Becker L. PepC: proteomics software for identifying differentially expressed proteins based on spectral counting. Bioinformatics 2010, 26(12):1574-1575. [Epub 2010/04/24].
30. Garde A.H., Hansen A.M., Kristiansen J., Knudsen L.E. Comparison of uncertainties related to standardization of urine samples with volume and creatinine concentration. Ann Occup Hyg 2004, 48(2):171-179. [Epub 2004/03/03].
31. Maere S., Heymans K., Kuiper M. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks. Bioinformatics 2005, 21(16):3448-3449. [Epub 2005/06/24].
32. Kushnir M.M., Mrozinski P., Rockwood A.L., Crockett D.K. A depletion strategy for improved detection of human proteins from urine. J Biomol Tech 2009, 20(2):101-108. [Epub 2009/06/09].
33. Adachi J., Kumar C., Zhang Y., Olsen J.V., Mann M. The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins. Genome Biol 2006, 7(9):R80. [Epub 2006/09/05].
34. Chen Y.T., Tsao C.Y., Li J.M., Tsai C.Y., Chiu S.F., Tseng T.L. Large-scale protein identification of human urine proteome by multi-dimensional LC and MS/MS. Proteomics Clin Appl 2007, 1(6):577-587. [Epub 2007/06/01].
35. Adedayo AM, Olafiranye O, Smith D, Hill A, Zizi F, Brown C, et al. Obstructive sleep apnea and dyslipidemia: evidence and underlying mechanism. Sleep & breathing = Schlaf & Atmung. 2012. Epub 2012/08/21.
36. Chorostowska-Wynimko J., Radomska D., Plywaczewski R., Jonczak L., Stepniewska A., Gorecka D., et al. Disturbed angiogenic activity in sera from obstructive sleep apnea patients. J Physiol Pharmacol 2005, 56(Suppl. 4):71-77. [Epub 2005/10/06].
37. Slupsky C.M., Rankin K.N., Wagner J., Fu H., Chang D., Weljie A.M., et al. Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Anal Chem 2007, 79(18):6995-7004. [Epub 2007/08/19].
38. von Kanel R., Loredo J.S., Ancoli-Israel S., Mills P.J., Natarajan L., Dimsdale J.E. Association between polysomnographic measures of disrupted sleep and prothrombotic factors. Chest 2007, 131(3):733-739. [Epub 2007/03/16].
39. Christensen B.C., Houseman E.A., Marsit C.J., Zheng S., Wrensch M.R., Wiemels J.L., et al. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS Genet. 2009, 5(8):e1000602. [Epub 2009/08/15].
40. La Thangue N.B., Kerr D.J. Predictive biomarkers: a paradigm shift towards personalized cancer medicine. Nat Rev Clin Oncol 2011, 8(10):587-596. [Epub 2011/08/25].
41. Stratz C., Amann M., Berg D.D., Morrow D.A., Neumann F.J., Hochholzer W. Novel biomarkers in cardiovascular disease: research tools or ready for personalized medicine?. Cardiol Rev 2012, 20(3):111-117. [Epub 2012/02/04].
42. Escudero J., Ifeachor E., Zajicek J., Green C., Shearer J., Pearson S. Machine learning-based method for personalized and cost-effective detection of Alzheimer's disease. IEEE Trans Bio-med Eng 2012, [Epub 2012/08/16].
43. Leary R.J., Kinde I., Diehl F., Schmidt K., Clouser C., Duncan C., et al. Development of personalized tumor biomarkers using massively parallel sequencing. Sci Transl Med 2010, 2(20):20ra14. [Epub 2010/04/08].
44. Verrills N.M., Irwin J.A., He X.Y., Wood L.G., Powell H., Simpson J.L., et al. Identification of novel diagnostic biomarkers for asthma and chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2011, 183(12):1633-1643. [Epub 2011/04/08].
45. Gozal D., Kheirandish-Gozal L. New approaches to the diagnosis of sleep-disordered breathing in children. Sleep Med 2010, 11(7):708-713. [Epub 2010/07/14].