MiRNA-155 controls mast cell activation by regulating the PI3Kγ pathway and anaphylaxis in a mouse model

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 69, Issue 6, 2014, Pages 752-762

  Biethahn, K ^a   Orinska, Z ^a   Vigorito, E ^b   Goyeneche Patino, D A ^a   Mirghomizadeh, F ^a   Foger N ^a,c   Bulfone Paus, S ^a,d  

^a RESEARCH CENTER BORSTEL   (Germany)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

allergy; anaphylaxis; mast cell degranulation; mast cells; miRNA

Indexed keywords

2,4 DINITROPHENOL; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 6; MICRORNA 155; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHOINOSITIDE 3 KINASE REGULATORY SUBUNIT 5; PHOSPHOINOSITIDE 3 KINASE REGULATORY SUBUNIT 6; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN KINASE LYN; PROTEIN KINASE SYK; SERINE; THREONINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; MICRORNA; MIRN155 MICRORNA, MOUSE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CG PROTEIN, MOUSE;

ALLERGIC REACTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ACTIVATION; CELL FUNCTION; CELL PROLIFERATION; CELL SIZE; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRANULATION; DOWN REGULATION; EAR SWELLING; GENE EXPRESSION PROFILING; IN VITRO STUDY; IN VIVO STUDY; MAST CELL; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SWELLING; ANAPHYLAXIS; ANIMAL; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHOSPHORYLATION;

ANAPHYLAXIS; ANIMALS; CELL DEGRANULATION; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; MAST CELLS; MICE; MICE, KNOCKOUT; MICRORNAS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84899985093     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12407     Document Type: Article

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