The unfolded protein response affects readthrough of premature termination codons

EMBO Molecular Medicine

Volumn 6, Issue 5, 2014, Pages 685-701

  Oren, Yifat S ^a   McClure, Michelle L ^b   Rowe, Steven M ^b   Sorscher, Eric J ^b   Bester, Assaf C ^a   Manor, Miriam ^a   Kerem, Eitan ^c   Rivlin, Joseph ^d   Zahdeh, Fouad ^a   Mann, Matthias ^e   Geiger, Tamar ^f   Kerem, Batsheva ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d CARMEL MEDICAL CENTER   (Israel)

^e MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^f TEL AVIV UNIVERSITY   (Israel)

Author keywords

Nonsense mediated mRNA decay; Premature termination codon; Readthrough treatment; Unfolded protein response

Indexed keywords

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; PROTEOME; STOP CODON;

ARTICLE; CELL FUNCTION; CODON; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEEDBACK SYSTEM; FEMALE; GENE MUTATION; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VIVO STUDY; NONSENSE MEDIATED MRNA DECAY; PREMATURE TERMINATION CODON; PRIORITY JOURNAL; PROTEIN FUNCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; PROTEIN SYNTHESIS; STOP CODON;

CODON, NONSENSE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HOMEOSTASIS; HUMANS; NONSENSE MEDIATED MRNA DECAY; PROTEIN BIOSYNTHESIS; PROTEOME; UNFOLDED PROTEIN RESPONSE;

EID: 84899952675     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201303347     Document Type: Article

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