Asynchronous activation of calcium and potassium currents by isoproterenol in canine ventricular myocytes

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 387, Issue 5, 2014, Pages 457-467

  Ruzsnavszky, Ferenc ^a   Hegyi, Bence ^a   Kistamás, Kornél ^a   Váczi, Krisztina ^a   Horváth, Balázs ^a   Szentandrássy, Norbert ^a   Bányász, Tamás ^a   Nánási, Péter P ^a   Magyar, János ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Action potential duration; Adrenergic activation; Calcium current; Dog myocytes; Potassium currents; Signal transduction

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CALCIUM; CYCLIC AMP; ISOPRENALINE; PHOSPHODIESTERASE; POTASSIUM; BETA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; POTASSIUM CHANNEL;

ACTION POTENTIAL; ADRENERGIC ACTIVITY; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CURRENT; CANINE VENTRICULAR MYOCYTE; CELL COMPARTMENTALIZATION; DOG; DRUG EXPOSURE; ENZYME INHIBITION; HEART MUSCLE CELL; MEMBRANE POTENTIAL; NONHUMAN; PATCH CLAMP TECHNIQUE; POTASSIUM CURRENT; SIGNAL TRANSDUCTION; VOLTAGE CLAMP TECHNIQUE; WHOLE CELL; ANIMAL; DRUG EFFECTS; FEMALE; HEART VENTRICLE; MALE; METABOLISM; PHYSIOLOGY;

ACTION POTENTIALS; ANIMALS; CALCIUM CHANNELS; DOGS; FEMALE; HEART VENTRICLES; ISOPROTERENOL; MALE; MYOCYTES, CARDIAC; POTASSIUM CHANNELS; RECEPTORS, ADRENERGIC, BETA;

EID: 84899931689     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-014-0964-6     Document Type: Article

References (46)

1. 2-adrenergic regulation. PNAS 103:7500-7505. doi:10.1073/pnas.0503465103
2. Bányász T, Fülöp L, Magyar J, Szentandrássy N, Varró A, Nánási PP (2003) Endocardial versus epicardial differences in L-type calcium current in canine ventricular myocytes studied by action potential voltage clamp. Cardiovasc Res 58:66-75. doi:10.1016/S0008-6363(02)00853-2
3. + currents in canine cardiomyocytes: their role in ventricular repolarization. Acta Physiol Scand 190:189-198. doi:10.1111/j.1748-1716.2007.01674.x
4. 2+ channels exhibit unique regulation and functional roles in cardiomyocytes. J Mol Cell Cardiol 52:376-387. doi:10.1016/j.yjmcc.2011.08.014
5. 2+ channels. Biophys J 79:2547-2556. doi:10.1016/S0006-3495(00)76495-2
6. 2+ channel Cav1.2. Science 293:98-101. doi:10.1126/science.293.5527.98
7. Doerr T, Denger R, Doerr A, TrautweinW(1990) Ionic currents contributing to the action potential in single ventricular myocytes of the guinea pig studied with action potential clamp. Pflugers Arch 416:230-237. doi:10.1007/BF00392058 (Pubitemid 20183290)
8. Fischmeister R, DeFelice LJ, Ayer RK, Levi R, DeHaan RL (1984) Channel currents during spontaneous action potentials in embryonic chick heart sells. The action potential patch clamp. Biophys J 46:267-271. doi:10.1016/S0006- 3495(84)84020-5
9. Frace M, Méry P-F, Fischmeister R, Hartzell HC (1993) Rate-limiting steps in the β-adrenergic stimulation of cardiac calcium current. J Gen Physiol 101:337-353. doi:10.1085/jgp.101.3.337 (Pubitemid 23106910)
10. + current in ventricular myocytes. Am J Physiol 266:H1551-H1557
11. + currents in canine ventricular cardiomyocytes. Br J Pharmacol 162:890-896. doi:10.2174/0929867043456214
12. Harvey RD, Clark CD, Hume JR (1990) Cl- current in mammalian cardiac myocytes: novel mechanism for autonomic regulation of action potential duration and resting membrane potential. J Gen Physiol 95:1077-1102. doi:10.1085/jgp.95. 6.1077 (Pubitemid 20217304)
13. Kr, through a reduction in C-type inactivation in guinea-pig ventricular myocytes. J Physiol Lond 522:391-402. doi:10.1111/j.1469-7793.2000.t01-2-0039
14. 2+-transient. J Mol Cell Cardiol 50:863-871. doi:10.1016/j.yjmcc.2011.02.007
15. 2+ current. Circ Res 64:977-990. doi:10.1161/01.RES.64.5.977
16. K1 to ventricular repolarization in canine and human myocytes. Is there any influence of action potential duration? Basic Res Cardiol 104:33-41. doi:10.1007/s00395-008-0730-3
17. 2-adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium. Quantitative discrepancies with binding and adenylate cyclase stimulation. Naunyn-Schmiedeberg's Arch Pharmacol 335:403-411. doi:10.1007/BF00165555
18. 2-adrenergic signaling. J Biol Chem 274:22048-22052. doi:10.1074/jbc.274.31.22048
19. 2-adrenergic cAMP signaling is uncoupled from phosphorylation of cytoplasmic proteins in canine heart. Circulation 99:2458-2465. doi:10.1161/01.CIR.99.18.2458
20. 3H-ICI 118,551 and blocking potency of ICI 118,551. Naunyn Schmiedeberg's Arch Pharmacol 331:40-51. doi:10.1007/BF00498850
21. Liu X-G, Choi B-R, Ziv O, Li W, de Lange E, Qu Z, Koren G (2012) Differential conditions for early after-depolarizations and triggered activity in cardiomyocytes derived fromtransgenic LQT1 and LQT2 rabbits. J Physiol Lond 590(5):1171-1180. doi:10.1113/jphysiol.2011.218164
22. McDonald TF, Pelzer S, Trautwein W, Pelzer DJ (1994) Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells. Physiol Rev 74:365-507 (Pubitemid 24127646)
23. 2+ current response to rapid applications of β-adrenergic and dihydropyridine agonists. Naunyn Schmiedeberg 's Arch Pharmacol 348:197 - 206. doi:10.1007/BF00164799
24. 2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation. Science 327:1653-1657. doi:10.1126/science.1185988
25. Post SR, Hammond HK, Insel PA (1999) β-adrenergic receptors and receptor signaling in heart failure. Annu Rev Pharmacol Toxicol 39:343-360. doi:10.1146/annurev.pharmtox.39.1.343 (Pubitemid 29222563)
26. Rocchetti M, Freli V, Perego V, Altomare C, Mostacciuolo G, Zaza A (2006) Rate dependency of beta-adrenergic modulation of repolarizing currents in the guinea-pig ventricle. J Physiol (Lond) 574:183-193. doi:10.1113/jphysiol.2006. 105015 (Pubitemid 43905806)
27. Simkó J, Szentandrássy N, Harmati G, Bárándi L, Horváth B, Magyar J, Bányász T, Lo″rincz I, Nánási PP (2010) Effects of ropinirole on action potential characteristics and the underlying ion currents in canine ventricular myocytes. Naunyn Schmiedeberg 's Arch Pharmacol 382:213-220. doi:10.1007/s00210-010-0538-1
28. 2+ current in cardiac myocytes. J Pharmacol Exp Ther 283:452-461
29. Steinberg SF, Brunton LL (2001) Compartmentalization of G protein-coupled signaling pathways in cardiac myocytes. Annu Rev Pharmacol Toxicol 41:751 -773. doi:10.1146/annurev.pharmtox.41.1.751
30. Ks) in canine ventricular myocytes. J Physiol Lond 551:777-786. doi:10.1113/jphysiol.2003.044040
31. Szabó G, Szentandrássy N, Bíró T, Tóth IB, Czifra G, Magyar J, Bányász T, Varró A, Kovács L, Nánási PP (2005) Asymmetrical distribution of ion channels in canine and human left ventricular wall: epicardium versus midmyocardium. Pflugers Arch 450:307-316. doi:10.1007/s00424-005-1445-z
32. Szabó L, Szentandrássy N, Kistamás K, Hegyi B, Ruzsnavszky F, Váczi K, Horváth B, Magyar J, Bányász T, Pál B, Nánási PP (2013) Effects of tacrolimus on action potential configuration and transmembrane ion currents in canine ventricular cells. Naunyn Schmiedeberg's Arch Pharmacol 386:239-246. doi:10.1007/s00210-012- 0823-2
33. Szentadrássy N, Bányász T, Bíró T, Szabó G, Tóth B, Magyar J, Lázár J, Varró A, Kovács L, Nánási PP (2005) Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium. Cardiovasc Res 65:851-860. doi:10.1016/j.cardiores. 2004.11.022
34. + currents to isoprenaline-induced changes in canine ventricular cells. Br J Pharmacol 167:599-611. doi:10.1111/j.1476-5381.2012.02015.x
35. Vandecasteele G, Rochais F, Abi-Gerges A, Fischmeister R (2006) Functional localization of cAMP signalling in cardiac myocytes. Biochem Soc Trans 34:484-488. doi:10.1042/BST0340484 (Pubitemid 44230742)
36. Van der Heyden MA, Wijnhoven TJ, Opthof T (2005) Molecular aspects of adrenergic modulation of cardiac L-type Ca2+ channels. Cardiovasc Res 65:28-39. doi:10.1016/j.cardiores.2004.09.028 (Pubitemid 40038476)
37. Ks in dog ventricular muscle and Purkinje fibre repolarization. J Physiol Lond 523:67-81. doi:10.1111/j.1469-7793.2000.00067.x
38. Ks to canine ventricular repolarization: key role for β-adrenergic receptor stimulation. Circulation 107:2753-2760. doi:10.1161/01.CIR.0000068344.54010.B3
39. Walsh KB, Begenisich T, Kass RS (1988) β-adrenergic modulation in the heart. Independent regulation of K and Ca channels. Pflugers Arch 411:232-234 (Pubitemid 18066974)
40. i proteins. Sci STKE 104:re15. doi:10.1126/stke.2001.104.re15
41. 2-adrenergic signal transduction. Circ Res 85: 1092-1100. doi:10.1161/01.RES.85.11.1092
42. 2+ dynamics, contractility, or phospholamban phosphorylation. J Biol Chem 269:19151-19156
43. 2-adrenoceptor to a pertussis toxin-sensitive G protein in cardiac myocytes. Mol Pharmacol 47:322-329. doi:10.1161/01.RES.84.1.43
44. 2+ current in single rat ventricular cells. Circ Res 73:286-300. doi:10.1161/01.RES.73.2.286
45. Xie Y, Grandi E, Puglisi JL, Sato D, Bers DM (2013) β-adrenergic stimulation activates early afterdepolarizations transiently via kinetic mismatch of PKA targets. J Mol Cell Cardiol 58:153-161
46. Zhu Y, Ai X, Oster RA, Bers DM, Pogwizd SM(2013) Sex differences in repolarization and slow delayed rectifier potassium current and their regulation by sympathetic stimulation in rabbits. Pflugers Arch 465:805-818. doi:10.1007/s00424-012-1193-9