-
1
-
-
2042501707
-
The neuronal primary cilium-an extrasynaptic signaling device
-
10.1016/j.cellsig.2003.12.002, 15115655
-
Whitfield JF. The neuronal primary cilium-an extrasynaptic signaling device. Cell Signal 2004, 16:763-767. 10.1016/j.cellsig.2003.12.002, 15115655.
-
(2004)
Cell Signal
, vol.16
, pp. 763-767
-
-
Whitfield, J.F.1
-
2
-
-
79955138852
-
Ciliopathies
-
10.1056/NEJMra1010172, 3640822, 21506742
-
Hildebrandt F, Benzing T, Katsanis N. Ciliopathies. N Engl J Med 2011, 364:1533-1543. 10.1056/NEJMra1010172, 3640822, 21506742.
-
(2011)
N Engl J Med
, vol.364
, pp. 1533-1543
-
-
Hildebrandt, F.1
Benzing, T.2
Katsanis, N.3
-
4
-
-
34548490748
-
Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease
-
10.1016/j.cub.2007.08.034, 2084209, 17825558
-
Davenport JR, Watts AJ, Roper VC, Croyle MJ, van Groen T, Wyss JM, Nagy TR, Kesterson RA, Yoder BK. Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol 2007, 17:1586-1594. 10.1016/j.cub.2007.08.034, 2084209, 17825558.
-
(2007)
Curr Biol
, vol.17
, pp. 1586-1594
-
-
Davenport, J.R.1
Watts, A.J.2
Roper, V.C.3
Croyle, M.J.4
van Groen, T.5
Wyss, J.M.6
Nagy, T.R.7
Kesterson, R.A.8
Yoder, B.K.9
-
5
-
-
0025627770
-
Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse
-
Coleman DL, Eicher EM. Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse. J Hered 1990, 81:424-427.
-
(1990)
J Hered
, vol.81
, pp. 424-427
-
-
Coleman, D.L.1
Eicher, E.M.2
-
6
-
-
15844372440
-
Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family
-
10.1016/S0092-8674(00)81104-6, 8612280
-
Kleyn PW, Fan W, Kovats SG, Lee JJ, Pulido JC, Wu Y, Berkemeier LR, Misumi DJ, Holmgren L, Charlat O, Woolf EA, Tayber O, Brody T, Shu P, Hawkins F, Kennedy B, Baldini L, Ebeling C, Alperin GD, Deeds J, Lakey ND, Culpepper J, Chen H, Glücksmann-Kuis MA, Carlson GA, Duyk GM, Moore KJ. Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family. Cell 1996, 85(2):281-290. 10.1016/S0092-8674(00)81104-6, 8612280.
-
(1996)
Cell
, vol.85
, Issue.2
, pp. 281-290
-
-
Kleyn, P.W.1
Fan, W.2
Kovats, S.G.3
Lee, J.J.4
Pulido, J.C.5
Wu, Y.6
Berkemeier, L.R.7
Misumi, D.J.8
Holmgren, L.9
Charlat, O.10
Woolf, E.A.11
Tayber, O.12
Brody, T.13
Shu, P.14
Hawkins, F.15
Kennedy, B.16
Baldini, L.17
Ebeling, C.18
Alperin, G.D.19
Deeds, J.20
Lakey, N.D.21
Culpepper, J.22
Chen, H.23
Glücksmann-Kuis, M.A.24
Carlson, G.A.25
Duyk, G.M.26
Moore, K.J.27
more..
-
7
-
-
0030006024
-
A candidate gene for the mouse mutation tubby
-
10.1038/380534a0, 8606774
-
Noben-Trauth K, Naggert JK, North MA, Nishina PM. A candidate gene for the mouse mutation tubby. Nature 1996, 380:534-538. 10.1038/380534a0, 8606774.
-
(1996)
Nature
, vol.380
, pp. 534-538
-
-
Noben-Trauth, K.1
Naggert, J.K.2
North, M.A.3
Nishina, P.M.4
-
8
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
10.1038/nature01279, 12529643
-
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 2003, 421:268-272. 10.1038/nature01279, 12529643.
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
Fraser, A.G.4
Kamath, R.S.5
Ahringer, J.6
Ruvkun, G.7
-
9
-
-
33644616841
-
Polygenic control of Caenorhabditis elegans fat storage
-
10.1038/ng1739, 16462744
-
Mak HY, Nelson LS, Basson M, Johnson CD, Ruvkun G. Polygenic control of Caenorhabditis elegans fat storage. Nat Genet 2006, 38:363-368. 10.1038/ng1739, 16462744.
-
(2006)
Nat Genet
, vol.38
, pp. 363-368
-
-
Mak, H.Y.1
Nelson, L.S.2
Basson, M.3
Johnson, C.D.4
Ruvkun, G.5
-
10
-
-
84883740776
-
Tubby is required for trafficking g protein-coupled receptors to neuronal cilia
-
10.1186/2046-2530-1-21, 3599646, 23351594
-
Sun X, Haley J, Bulgakovoleg OV, Cai X, McGinnis J, Li T. Tubby is required for trafficking g protein-coupled receptors to neuronal cilia. Cilia 2012, 1:21. 10.1186/2046-2530-1-21, 3599646, 23351594.
-
(2012)
Cilia
, vol.1
, pp. 21
-
-
Sun, X.1
Haley, J.2
Bulgakovoleg, O.V.3
Cai, X.4
McGinnis, J.5
Li, T.6
-
11
-
-
0345561551
-
Selective targeting of somatostatin receptor 3 to neuronal cilia
-
10.1016/S0306-4522(98)00354-6, 10199624
-
Handel M, Schulz S, Stanarius A, Schreff M, Erdtmann-Vourliotis M, Schmidt H, Wolf G, Hollt V. Selective targeting of somatostatin receptor 3 to neuronal cilia. Neuroscience 1999, 89:909-926. 10.1016/S0306-4522(98)00354-6, 10199624.
-
(1999)
Neuroscience
, vol.89
, pp. 909-926
-
-
Handel, M.1
Schulz, S.2
Stanarius, A.3
Schreff, M.4
Erdtmann-Vourliotis, M.5
Schmidt, H.6
Wolf, G.7
Hollt, V.8
-
12
-
-
41949116864
-
Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia
-
10.1073/pnas.0711027105, 2393805, 18334641
-
Berbari NF, Lewis JS, Bishop GA, Askwith CC, Mykytyn K. Bardet-Biedl syndrome proteins are required for the localization of G protein-coupled receptors to primary cilia. Proc Natl Acad Sci USA 2008, 105:4242-4246. 10.1073/pnas.0711027105, 2393805, 18334641.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4242-4246
-
-
Berbari, N.F.1
Lewis, J.S.2
Bishop, G.A.3
Askwith, C.C.4
Mykytyn, K.5
-
13
-
-
4444254983
-
Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
-
10.1038/ng1418, 15322545
-
Kulaga HM, Leitch CC, Eichers ER, Badano JL, Lesemann A, Hoskins BE, Lupski JR, Beales PL, Reed RR, Katsanis N. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat Genet 2004, 36:994-998. 10.1038/ng1418, 15322545.
-
(2004)
Nat Genet
, vol.36
, pp. 994-998
-
-
Kulaga, H.M.1
Leitch, C.C.2
Eichers, E.R.3
Badano, J.L.4
Lesemann, A.5
Hoskins, B.E.6
Lupski, J.R.7
Beales, P.L.8
Reed, R.R.9
Katsanis, N.10
-
14
-
-
79959676965
-
The tubby family proteins
-
10.1186/gb-2011-12-6-225, 3218838, 21722349
-
Mukhopadhyay S, Jackson PK. The tubby family proteins. Genome Biol 2011, 12:225. 10.1186/gb-2011-12-6-225, 3218838, 21722349.
-
(2011)
Genome Biol
, vol.12
, pp. 225
-
-
Mukhopadhyay, S.1
Jackson, P.K.2
-
15
-
-
0035874921
-
G-protein signaling through tubby proteins
-
10.1126/science.1061233, 11375483
-
Santagata S, Boggon TJ, Baird CL, Gomez CA, Zhao J, Shan WS, Myszka DG, Shapiro L. G-protein signaling through tubby proteins. Science 2001, 292:2041-2050. 10.1126/science.1061233, 11375483.
-
(2001)
Science
, vol.292
, pp. 2041-2050
-
-
Santagata, S.1
Boggon, T.J.2
Baird, C.L.3
Gomez, C.A.4
Zhao, J.5
Shan, W.S.6
Myszka, D.G.7
Shapiro, L.8
-
16
-
-
77957682469
-
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
-
10.1101/gad.1966210, 2947770, 20889716
-
Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Genes Dev 2010, 24:2180-2193. 10.1101/gad.1966210, 2947770, 20889716.
-
(2010)
Genes Dev
, vol.24
, pp. 2180-2193
-
-
Mukhopadhyay, S.1
Wen, X.2
Chih, B.3
Nelson, C.D.4
Lane, W.S.5
Scales, S.J.6
Jackson, P.K.7
-
17
-
-
65449124963
-
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
-
10.1093/hmg/ddp113, 2671991, 19286674
-
Norman RX, Ko HW, Huang V, Eun CM, Abler LL, Zhang Z, Sun X, Eggenschwiler JT. Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling. Hum Mol Genet 2009, 18:1740-1754. 10.1093/hmg/ddp113, 2671991, 19286674.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 1740-1754
-
-
Norman, R.X.1
Ko, H.W.2
Huang, V.3
Eun, C.M.4
Abler, L.L.5
Zhang, Z.6
Sun, X.7
Eggenschwiler, J.T.8
-
18
-
-
0032542294
-
Mice lacking melanin-concentrating hormone are hypophagic and lean
-
10.1038/25341, 9872314
-
Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 1998, 396:670-674. 10.1038/25341, 9872314.
-
(1998)
Nature
, vol.396
, pp. 670-674
-
-
Shimada, M.1
Tritos, N.A.2
Lowell, B.B.3
Flier, J.S.4
Maratos-Flier, E.5
-
19
-
-
18444375866
-
Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity
-
10.1210/en.143.7.2469, 12072376
-
Chen Y, Hu C, Hsu CK, Zhang Q, Bi C, Asnicar M, Hsiung HM, Fox N, Slieker LJ, Yang DD, Heiman ML, Shi Y. Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology 2002, 143:2469-2477. 10.1210/en.143.7.2469, 12072376.
-
(2002)
Endocrinology
, vol.143
, pp. 2469-2477
-
-
Chen, Y.1
Hu, C.2
Hsu, C.K.3
Zhang, Q.4
Bi, C.5
Asnicar, M.6
Hsiung, H.M.7
Fox, N.8
Slieker, L.J.9
Yang, D.D.10
Heiman, M.L.11
Shi, Y.12
-
20
-
-
0035134670
-
Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
-
10.1172/JCI10660, 199192, 11160162
-
Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 2001, 107:379-386. 10.1172/JCI10660, 199192, 11160162.
-
(2001)
J Clin Invest
, vol.107
, pp. 379-386
-
-
Ludwig, D.S.1
Tritos, N.A.2
Mastaitis, J.W.3
Kulkarni, R.4
Kokkotou, E.5
Elmquist, J.6
Lowell, B.7
Flier, J.S.8
Maratos-Flier, E.9
-
21
-
-
70349180860
-
Adult type 3 adenylyl cyclase-deficient mice are obese
-
10.1371/journal.pone.0006979, 2735775, 19750222
-
Wang Z, Li V, Chan GC, Phan T, Nudelman AS, Xia Z, Storm DR. Adult type 3 adenylyl cyclase-deficient mice are obese. PLoS One 2009, 4:e6979. 10.1371/journal.pone.0006979, 2735775, 19750222.
-
(2009)
PLoS One
, vol.4
-
-
Wang, Z.1
Li, V.2
Chan, G.C.3
Phan, T.4
Nudelman, A.S.5
Xia, Z.6
Storm, D.R.7
-
22
-
-
0034525477
-
The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways
-
10.1210/en.141.12.4524, 11108264
-
Hawes BE, Kil E, Green B,O'Neill K, Fried S, Graziano MP. The melanin-concentrating hormone receptor couples to multiple G proteins to activate diverse intracellular signaling pathways. Endocrinology 2000, 141:4524-4532. 10.1210/en.141.12.4524, 11108264.
-
(2000)
Endocrinology
, vol.141
, pp. 4524-4532
-
-
Hawes, B.E.1
Kil, E.2
Green, B.3
O'4
Neill, K.5
Fried, S.6
Graziano, M.P.7
-
23
-
-
0042816504
-
Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways
-
10.1210/en.2002-0004, 12865333
-
Pissios P, Trombly DJ, Tzameli I, Maratos-Flier E. Melanin-concentrating hormone receptor 1 activates extracellular signal-regulated kinase and synergizes with G(s)-coupled pathways. Endocrinology 2003, 144:3514-3523. 10.1210/en.2002-0004, 12865333.
-
(2003)
Endocrinology
, vol.144
, pp. 3514-3523
-
-
Pissios, P.1
Trombly, D.J.2
Tzameli, I.3
Maratos-Flier, E.4
-
24
-
-
77956507253
-
DISC1 regulates primary cilia that display specific dopamine receptors
-
10.1371/journal.pone.0010902, 2878344, 20531939
-
Marley A, von Zastrow M. DISC1 regulates primary cilia that display specific dopamine receptors. PLoS One 2010, 5:e10902. 10.1371/journal.pone.0010902, 2878344, 20531939.
-
(2010)
PLoS One
, vol.5
-
-
Marley, A.1
von Zastrow, M.2
-
25
-
-
77951101203
-
The primary cilium: a signalling centre during vertebrate development
-
10.1038/nrg2774, 3121168, 20395968
-
Goetz SC, Anderson KV. The primary cilium: a signalling centre during vertebrate development. Nat Rev Genet 2010, 11:331-344. 10.1038/nrg2774, 3121168, 20395968.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 331-344
-
-
Goetz, S.C.1
Anderson, K.V.2
-
26
-
-
34848902919
-
Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool
-
10.1523/JNEUROSCI.5586-06.2007, 17804638
-
Chizhikov VV, Davenport J, Zhang Q, Shih EK, Cabello OA, Fuchs JL, Yoder BK, Millen KJ. Cilia proteins control cerebellar morphogenesis by promoting expansion of the granule progenitor pool. J Neurosci 2007, 27:9780-9789. 10.1523/JNEUROSCI.5586-06.2007, 17804638.
-
(2007)
J Neurosci
, vol.27
, pp. 9780-9789
-
-
Chizhikov, V.V.1
Davenport, J.2
Zhang, Q.3
Shih, E.K.4
Cabello, O.A.5
Fuchs, J.L.6
Yoder, B.K.7
Millen, K.J.8
-
27
-
-
12144262775
-
Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis
-
10.1523/JNEUROSCI.1108-04.2005, 15634762
-
Spassky N, Merkle FT, Flames N, Tramontin AD, Garcia-Verdugo JM, Alvarez-Buylla A. Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis. J Neurosci 2005, 25:10-18. 10.1523/JNEUROSCI.1108-04.2005, 15634762.
-
(2005)
J Neurosci
, vol.25
, pp. 10-18
-
-
Spassky, N.1
Merkle, F.T.2
Flames, N.3
Tramontin, A.D.4
Garcia-Verdugo, J.M.5
Alvarez-Buylla, A.6
-
28
-
-
51349167818
-
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling
-
10.1073/pnas.0804558105, 2529104, 18728187
-
Breunig JJ, Sarkisian MR, Arellano JI, Morozov YM, Ayoub AE, Sojitra S, Wang B, Flavell RA, Rakic P, Town T. Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling. Proc Natl Acad Sci USA 2008, 105:13127-13132. 10.1073/pnas.0804558105, 2529104, 18728187.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13127-13132
-
-
Breunig, J.J.1
Sarkisian, M.R.2
Arellano, J.I.3
Morozov, Y.M.4
Ayoub, A.E.5
Sojitra, S.6
Wang, B.7
Flavell, R.A.8
Rakic, P.9
Town, T.10
-
29
-
-
69949166247
-
Dual and opposing roles of primary cilia in medulloblastoma development
-
10.1038/nm.2020, 2771737, 19701203
-
Han YG, Kim HJ, Dlugosz AA, Ellison DW, Gilbertson RJ, Alvarez-Buylla A. Dual and opposing roles of primary cilia in medulloblastoma development. Nat Med 2009, 15:1062-1065. 10.1038/nm.2020, 2771737, 19701203.
-
(2009)
Nat Med
, vol.15
, pp. 1062-1065
-
-
Han, Y.G.1
Kim, H.J.2
Dlugosz, A.A.3
Ellison, D.W.4
Gilbertson, R.J.5
Alvarez-Buylla, A.6
-
30
-
-
79960035427
-
Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory
-
10.1523/JNEUROSCI.1062-11.2011, 21734285
-
Amador-Arjona A, Elliott J, Miller A, Ginbey A, Pazour GJ, Enikolopov G, Roberts AJ, Terskikh AV. Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory. J Neurosci 2011, 31:9933-9944. 10.1523/JNEUROSCI.1062-11.2011, 21734285.
-
(2011)
J Neurosci
, vol.31
, pp. 9933-9944
-
-
Amador-Arjona, A.1
Elliott, J.2
Miller, A.3
Ginbey, A.4
Pazour, G.J.5
Enikolopov, G.6
Roberts, A.J.7
Terskikh, A.V.8
-
31
-
-
70349783742
-
Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain
-
10.1016/j.ydbio.2009.08.023, 2778284, 19732765
-
Stottmann RW, Tran PV, Turbe-Doan A, Beier DR. Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol 2009, 335:166-178. 10.1016/j.ydbio.2009.08.023, 2778284, 19732765.
-
(2009)
Dev Biol
, vol.335
, pp. 166-178
-
-
Stottmann, R.W.1
Tran, P.V.2
Turbe-Doan, A.3
Beier, D.R.4
-
32
-
-
58149383262
-
A crucial role for primary cilia in cortical morphogenesis
-
10.1523/JNEUROSCI.2084-08.2008, 19036983
-
Willaredt MA, Hasenpusch-Theil K, Gardner HA, Kitanovic I, Hirschfeld-Warneken VC, Gojak CP, Gorgas K, Bradford CL, Spatz J, Wolfl S, Theil T, Tucker KL. A crucial role for primary cilia in cortical morphogenesis. J Neurosci 2008, 28:12887-12900. 10.1523/JNEUROSCI.2084-08.2008, 19036983.
-
(2008)
J Neurosci
, vol.28
, pp. 12887-12900
-
-
Willaredt, M.A.1
Hasenpusch-Theil, K.2
Gardner, H.A.3
Kitanovic, I.4
Hirschfeld-Warneken, V.C.5
Gojak, C.P.6
Gorgas, K.7
Bradford, C.L.8
Spatz, J.9
Wolfl, S.10
Theil, T.11
Tucker, K.L.12
-
33
-
-
84862776613
-
A role for primary cilia in glutamatergic synaptic integration of adult-born neurons
-
S1, 10.1038/nn.3042, 3288565, 22306608
-
Kumamoto N, Gu Y, Wang J, Janoschka S, Takemaru K, Levine J, Ge S. A role for primary cilia in glutamatergic synaptic integration of adult-born neurons. Nat Neurosci 2012, 15:399-405. S1, 10.1038/nn.3042, 3288565, 22306608.
-
(2012)
Nat Neurosci
, vol.15
, pp. 399-405
-
-
Kumamoto, N.1
Gu, Y.2
Wang, J.3
Janoschka, S.4
Takemaru, K.5
Levine, J.6
Ge, S.7
-
34
-
-
77949816722
-
Somatostatin signaling in neuronal cilia is critical for object recognition memory
-
10.1523/JNEUROSCI.5295-09.2010, 20335466
-
Einstein EB, Patterson CA, Hon BJ, Regan KA, Reddi J, Melnikoff DE, Mateer MJ, Schulz S, Johnson BN, Tallent MK. Somatostatin signaling in neuronal cilia is critical for object recognition memory. J Neurosci 2010, 30:4306-4314. 10.1523/JNEUROSCI.5295-09.2010, 20335466.
-
(2010)
J Neurosci
, vol.30
, pp. 4306-4314
-
-
Einstein, E.B.1
Patterson, C.A.2
Hon, B.J.3
Regan, K.A.4
Reddi, J.5
Melnikoff, D.E.6
Mateer, M.J.7
Schulz, S.8
Johnson, B.N.9
Tallent, M.K.10
-
35
-
-
0029997176
-
D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses
-
Otmakhova NA, Lisman JE. D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses. J Neurosci 1996, 16:7478-7486.
-
(1996)
J Neurosci
, vol.16
, pp. 7478-7486
-
-
Otmakhova, N.A.1
Lisman, J.E.2
|