Nuclear NF-κB contributes to chlorpyrifos-induced apoptosis through p53 signaling in human neural precursor cells

NeuroToxicology

Volumn 42, Issue , 2014, Pages 58-70

  Lee, Jeong Eun ^a,b   Lim, Mi Sun ^a,b   Park, Jae Hyeon ^a,b   Park, Chang Hwan ^a,b   Koh, Hyun Chul ^a,b  

^a Hanyang University   (South Korea)

^b Hanyang Biomedical Research Institute   (South Korea)

Author keywords

Chlorpyrifos; Human neural precursor cells; NF B; P53; Reactive oxidative species

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 9; CHLORPYRIFOS; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTATE DEHYDROGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; REACTIVE OXYGEN METABOLITE; INSECTICIDE; MALONALDEHYDE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DOWN REGULATION; DRUG TARGETING; ENZYME ACTIVATION; ENZYME RELEASE; HUMAN; HUMAN CELL; NEURAL STEM CELL; NEUROTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; OXIDATIVE STRESS; PATHOLOGY;

ACETYLCYSTEINE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELLS, CULTURED; CHLORPYRIFOS; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INSECTICIDES; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; NEURAL STEM CELLS; NF-KAPPA B; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84899892604     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.04.001     Document Type: Article

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