Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor κB to modulate tumour necrosis factor-induced apoptosis: Evidence from mitochondria-targeted antioxidants

Biochemical Journal

Volumn 389, Issue 1, 2005, Pages 83-89

  Hughes, Gillian ^a,b   Murphy, Michael P ^a,b   Ledgerwood, Elizabeth C ^a,b  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Antioxidant; Caspase; Mitochondria; Nuclear factor B; Reactive oxygen species; Tumour necrosis factor

Indexed keywords

ACTIVATION ENERGY; ANTIOXIDANTS; CALCIUM; CYTOLOGY; PROTEINS; TUMORS; VITAMINS;

APOPTOSIS; HOMEOSTASIS; MITOCHONDRIA; REACTIVE OXYGEN SPECIES (ROS);

CELLS;

[2 (3,4 DIHYDRO 6 HYDROXY 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 2YL)ETHYL]TRIPHENYLPHOSPHONIUM BROMIDE; ANTIOXIDANT; BROMINE DERIVATIVE; CASPASE 3; CASPASE 8; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANALYSIS OF VARIANCE; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CELL STRAIN U937; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; MITOCHONDRION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; JURKAT CELLS; MITOCHONDRIA; NF-KAPPA B; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS;

EID: 22144432216     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050078     Document Type: Article

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