The ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation

Toxicological Sciences

Volumn 139, Issue 1, 2014, Pages 121-132

  Kurita, Hisaka ^a   Schnekenburger, Michael ^a,b   Ovesen, Jerald L ^a   Xia, Ying ^a   Puga, Alvaro ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b LABORATOIRE DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE DU CANCER   (Luxembourg)

Author keywords

Aryl hydrocarbon receptor; Chromatin histone modifications; Epigenetics; Gene regulation; Inhibitor of nuclear factor kappa B kinase subunit alpha; Protein kinases

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE 3A1; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; HISTONE H3; I KAPPA B KINASE ALPHA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NADPH DEPENDENT QUINONE OXYDOREDUCTASE 1; OXIDOREDUCTASE; SERINE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; HISTONE; I KAPPA B KINASE; MITOGEN AND STRESS-ACTIVATED PROTEIN KINASE 1; RPS6KA4 PROTEIN, MOUSE; S6 KINASE;

ANIMAL CELL; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME CONDENSATION; CONTROLLED STUDY; ENHANCER REGION; EPIGENETICS; HISTONE PHOSPHORYLATION; LIVER CELL CARCINOMA; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN TARGETING; TRANSCRIPTION INITIATION; ANIMAL; BINDING SITE; CHEMISTRY; CHROMATIN IMMUNOPRECIPITATION; DIMERIZATION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; TOXICITY; TUMOR CELL LINE;

ANIMALS; BINDING SITES; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CYTOCHROME P-450 CYP1A1; DIMERIZATION; ENHANCER ELEMENTS, GENETIC; HISTONES; I-KAPPA B KINASE; MICE; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA; SERINE; TETRACHLORODIBENZODIOXIN; TRANSCRIPTIONAL ACTIVATION;

EID: 84899861742     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu027     Document Type: Article

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