The curative effect of fucoidan on visceral leishmaniasis is mediated by activation of MAP kinases through specific protein kinase C isoforms

Cellular and Molecular Immunology

Volumn 11, Issue 3, 2014, Pages 263-274

  Sharma, Gunjan ^a   Kar, Susanta ^a   Basu Ball, Writoban ^a   Ghosh, Kuntal ^b   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b UNIVERSITY OF CALCUTTA   (India)

Author keywords

fucoidan; MAPK; NF B; PKC; visceral leishmaniasis

Indexed keywords

FUCOIDIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C BETAI; PROTEIN KINASE C BETAII; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PROTEIN KINASE C BETA I; PROTEIN KINASE C BETA II; SYNAPTOPHYSIN; 2-AMINO-5,6-DIHYDRO-6-METHYL-4H-1,3-THIAZINE; AUTACOID; MONOCLONAL ANTIBODY; POLYSACCHARIDE; THIAZINE DERIVATIVE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME INHIBITION; FEMALE; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; MACROPHAGE; MOUSE; NONHUMAN; PARASITE CLEARANCE; PROTEIN DNA BINDING; SIGNAL TRANSDUCTION; VISCERAL LEISHMANIASIS; WESTERN BLOTTING; ANTILEISHMANIAL ACTIVITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; GENE SILENCING; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DRUG EFFECTS; ENZYMOLOGY; IMMUNITY; IMMUNOLOGY; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; METABOLISM; PARASITOLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; ENZYME ACTIVATION; IMMUNITY; INFLAMMATION MEDIATORS; ISOENZYMES; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MAP KINASE SIGNALING SYSTEM; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; POLYSACCHARIDES; PROTEIN KINASE C; THIAZINES; TRANSCRIPTION FACTOR AP-1;

EID: 84899809675     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2013.68     Document Type: Article

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