Signaling events leading to the curative effect of cystatin on experimental visceral leishmaniasis: Involvement of ERK1/2, NF-κB and JAK/STAT pathways

European Journal of Immunology

Volumn 39, Issue 3, 2009, Pages 741-751

  Kar, Susanta ^a   Ukil, Anindita ^a   Das, Pijush K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Cystatin; Leishmaniasis; Macrophage; Nitricoxide; Signal transduction

Indexed keywords

CYSTATIN; GAMMA INTERFERON; I KAPPA B; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; STAT PROTEIN; SYNAPTOTAGMIN I; CYSTEINE PROTEINASE INHIBITOR; NITRIC OXIDE; NOS2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER COMBINATION CHEMOTHERAPY; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DNA BINDING; DRUG EFFICACY; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; GENE ACTIVITY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; IMMUNIZATION; LOW DRUG DOSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TREATMENT DURATION; TREATMENT RESPONSE; UPREGULATION; VISCERAL LEISHMANIASIS; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; DISEASE MODEL; DRUG ANTAGONISM; IMMUNOLOGY; MACROPHAGE; METABOLISM; PARASITOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; CYSTATINS; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; I-KAPPA B PROTEINS; INTERFERON-GAMMA; JANUS KINASES; LEISHMANIASIS, VISCERAL; MACROPHAGES; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS;

EID: 64049093545     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838465     Document Type: Article

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