Altered tyrosine phosphorylation of ERK1 MAP kinase and other macrophage molecules caused by Leishmania amastigotes

Molecular and Biochemical Parasitology

Volumn 102, Issue 1, 1999, Pages 1-12

  Martiny, Andrea ^a   Meyer Fernandes, José R ^a   De Souza, Wanderley ^a   Vannier Santos, Marcos A ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

Leishmania amastigotes; Macrophage; Protein phosphatase; Tyrosine phosphorylation

Indexed keywords

GELDANAMYCIN; GENISTEIN; HERBIMYCIN A; MITOGEN ACTIVATED PROTEIN KINASE; TYROSINE; TYRPHOSTIN; VANADATE SODIUM;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DEPHOSPHORYLATION; HOST PARASITE INTERACTION; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LEISHMANIA; MACROPHAGE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ANIMALS; BLOTTING, WESTERN; HUMANS; LEISHMANIA; MACROPHAGES, PERITONEAL; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTYROSINE; PRECIPITIN TESTS; VIRULENCE;

LEISHMANIA AMAZONENSIS; MURINAE;

EID: 0032782792     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(99)00067-5     Document Type: Article

References (47)

1. Greenberg S. Signal transduction during phagocytosis. Trends Cell. Biol. 5:1995;93-99.
2. Wei H., Wei L., Frenkel K., Bowen R., Barnes S. Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein. Nutr. Cancer. 20:1993;1-12.
3. Dong Z., Qi X., Xie K., Fidler I.J. Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages. J. Immunol. 151:1993;2717-2724.
4. Martiny A., Vannier-Santos M.A., Borges V.M., Meyer-Fernandes J.R., Asrreuy J., Cunha-e-Silva N.L., De Souza W. Leishmania-induced tyrosine phosphorylation in the host macrophage and its implication to infection. Eur. J. Cell. Biol. 71:1996;206-215.
5. Reiner N.E. Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection. Immunol. Today. 15:1994;374-381.
6. Reiner N.E. Parasite-accessory cell interactions in murine leishmaniasis. 1. evasion of stimulus-dependent suppression of the macrophage interleukin 1 response by Leishmania donovani. J. Immunol. 138:1987;1919-1925.
7. + T cells during initiation of infection. J. Exp. Med. 179:1994;447-456.
8. Kwan W.C., McMaster W.R., Wong N., Reiner N.E. Inhibition of expression of major histocompatibility complex class II molecules in macrophages infected with Leishmania donovani occurs at the level of gene transcription via a cyclic AMP-independent mechanisms. Infect. Immun. 60:1992;2115-2120.
9. 2+. Parasitol. Today. 12:1996;145-150.
10. Reiner N.E., Malemud C.J. Arachidonic acid metabolism by murine peritoneal macrophages infected with Leishmania donovani: in vitro evidence for parasite-induced alterations in cyclooxygenase and lipoxygenase pathways. J. Immunol. 134:1985;556-563.
11. Descouteaux A., Turco S.J. The lipophosphoglycan of Leishmania and macrophage protein kinase C. Parasitol. Today. 9:1993;468-471.
12. Moore K.J., Labrecque S., Matlashewski G. Alterations of Leishmania donovani infection levels by selective impairment of macrophages signal transduction. J. Immunol. 150:1993;4457-4465.
13. Moore K.J., Matlashswski G. Intracellular infection by Leishmania donovani inhibits macrophage apoptosis. J. Immunol. 152:1994;2930-2937.
14. Wilson B.C. Leishmaniasis: a worldwide problem. Int. J. Dermatol. 28:1989;305-307.
15. Olivier M., Romero-Gallo B.J., Matte C., Blanchette J., Posner B.I., Tremblay M.J., Faure R. Modulation of interferon-γ-induced macrophage activation by phosphotyrosine phosphatases inhibition: effect on murine leishmaniasis progression. J. Biol. Chem. 273:1998;13944-13949.
16. 2-terminal kinase. J. Biol. Chem. 272:1998;15920-15927.
17. Saraiva E.M.B., Pimenta P.F.P., Pereira M.E.A., De Souza W. Isolation and purification of amastigotes of Leishmania mexicana amazonensis by a gradient of metrizamide. J. Parasitol. 69:1983;627-629.
18. Bates P.A. Complete developmental cycle of Leishmania mexicana in axenic culture. Parasitology. 108:1993;1-9.
19. Gordon J. Use of vanadate as protein phosphotyrosine phosphatase inhibitor. Methods Enzymol. 201:1991;477-482.
20. Vannier-Santos M.A., Martiny A., Meyer-Fernandes J.R., De Souza W. Leishmanial protein kinase C may regulate parasite infection via secreted acid phosphatase. Eur. J. Cell. Biol. 67:1995;112-119.
21. Greenberg S., Chang P., Silverstein S.C. Tyrosine phosphorylation is required for Fc receptor-mediated phagocytosis in mouse macrophages. J. Exp. Med. 177:1993;529-534.
22. Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
23. Mosser D.M., Springer T.A., Diamond M.S. Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18). J. Cell. Biol. 116:1992;511-520.
24. Love D.C., Kane M.M., Mosser D.M. Leishmania amazonensis: the phagocytosis of amastigotes by macrophages. Exp. Parasitol. 88:1998;161-171.
25. Bliska J.B., Galn J.E., Falkow S. Signal transduction in the mammalian cell during bacterial attachment and entry. Cell. 73:1993;903-920.
26. Finlay B.B., Cossart P. Exploitation of mammalian host cell functions by bacterial pathogens. Science. 276:1997;718-725.
27. Furuya T., Zhong L., Meyer-Fernandes J.R., Lu H.G., Moreno S.N.J., Docampo R. Ecto-protein tyrosine phosphatase in Trypanosoma cruzi infective stages. Mol. Biochem. Parasitol. 92:1998;339-348.
28. Zhong L., Lu H.G., Moreno S.N.J., Docampo R. Tyrosine phosphate hydrolysis of host proteins by Trypanosoma cruzi is linked to invasion. FEMS Microbiol. Lett. 161:1998;15-20.
29. Li H.C., Chernoff J., Chen L.B., Kirschonbaun A. A phosphotyrosyl-protein phosphatase activity associated with acid phosphatase from human prostate gland. Eur. J. Biochem. 138:1993;45-51.
30. Lau K.H.W., Farley J.R., Baylink D.J. Phosphotyrosyl protein phosphatases. Biochem. J. 257:1989;23-36.
31. Shibata K.I., Noda M., Sawa Y., Watanabe T. Acid phosphatase purified from Mycoplasma fermentans has protein tyrosine phosphatase-like activity. Infect. Immun. 62:1994;313-315.
32. Lovelace J.K., Dwyer D.M., Gottlieb M. Purification and characterization of the extracellular acid phosphatase of Leishmania donovani. Mol. Biochem. Parasitol. 20:1986;243-251.
33. Katakura K., Kobayashi A. Acid phosphatase activity of virulent and avirulent clones of Leishmania donovani promastigotes. Infect. Immun. 56:1988;2856-2860.
34. Hakansson S., Schesser K., Persson C., Galyov E.E., Rosquvist R., Homblé F., Wolf-Watz H. The YopB protein of Yersinia pseudotuberculosisis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity. EMBO J. 15:1996;5812-5823.
35. Noronha F.S.M., Ramalho-Pinto F.J., Horta M.F. Cytolytic activity in the genus Leishmania: involvement of a putative pore-forming protein. Infect. Immun. 64:1996;3975-3982.
36. Akiyama T., Ogawara H. Use and specificity of genistein as inhibitor of protein tyrosine kinases. Methods Enzymol. 201:1991;362-370.
37. Nandan D., Reiner N.E. Attenuation of gamma-interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through janus kinases and stat 1. Infect. Immun. 63:1995;4495-4500.
38. Barral-Netto M., Barral A., Brownell C.E., Skeiky Y.A.W., Ellingsworth L.R., Twardzik D.R., Reed S.G. Transforming growth factor-β in leishmanial infection: parasite escape mechanisms. Science. 257:1992;545-548.
39. Yamaguchi K., Shirakabe K., Shybuya H., Irie K., Oishi I., Ueno N., Taniguchi T., Nishida E., Matsumoto K. Identification of a member of the MAPKKK family as a potential mediator of the TGF-β signal transduction. Science. 270:1995;2008-2011.
40. Davis R.J. The mitogen-activated protein kinase signal transduction pathway. J. Biol. Chem. 268:1993;14553-14556.
41. Winston L.A., Hunter T. Intracellular signalling: putting JAKs on the kinase MAP. Curr. Biol. 6:1996;668-671.
42. Dong Z., Qi X., Fidler I.J. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J. Exp. Med. 177:1993;1071-1077.
43. Reiner N.E., Ng W., Wilson C.B., McCaster R., Burchett S.T. Modulation of in vitro monocyte cytokine responses to Leishmania donovani: interferon-γ prevents parasite-induced inhibition of interleukin 1 production and primes monocytes to respond to Leishmania by producing both tumor necrosis factor-α and interleukin 1. J. Clin. Invest. 85:1990;1914-1924.
44. Weinstein S.L., Gold M.R., DeFranco A.L. Bacterial lipopolisaccharide sitimulates protein tyrosine phosphorylation in macrophages. Proc. Natl. Acad. Sci. USA. 88:1991;4148-4152.
45. Sanguedolce M.V., Capo C., Bouhamdan M., Bongrand P., Huang C.K., Mege J.L. Zymosan-induced tyrosine phosphorylations in human monocytes: role of protein kinase C. J. Immunol. 151:1993;405-414.
46. Geng Y., Gulbins E., Altman A., Lotz M. Monocyte deactivation by interleukin 10 via inhibition of tyrosine kinase activity and the Ras signaling pathway. Proc. Natl. Acad. Sci. USA. 91:1994;8602-8606.
47. Akuffo H., Maasho K., Blostedt M., Hojeberg B., Britton S., Bakhiet M. Leishmania aethiopica derived from diffuse leishmaniasis patients preferentially induce mRNA for interleukin-10 while those from localized leishmaniasis patients induce interferon-γ J. Infect. Dis. 175:1997;737-741.