Protective effect of acetyl-l-carnitine on propofol-induced toxicity in embryonic neural stem cells

NeuroToxicology

Volumn 42, Issue , 2014, Pages 49-57

  Liu, Fang ^a   Rainosek, Shuo W ^b   Sadovova, Natalya ^c   Fogle, Charles M ^a   Patterson, Tucker A ^a   Hanig, Joseph P ^d   Paule, Merle G ^a   Slikker Jr , William ^a   Wang, Cheng ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^c Toxicologic Pathology Associates   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Apoptosis; Neural stem cells; Propofol; Protection

Indexed keywords

8 HYDROXYGUANINE; LACTASE; LACTATE DEHYDROGENASE; LEVACECARNINE; PROPOFOL; REACTIVE OXYGEN METABOLITE; 4 AMINOBUTYRIC ACID A RECEPTOR; ACETYLCARNITINE; INTRAVENOUS ANESTHETIC AGENT; NEUROPROTECTIVE AGENT;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CELL DIVISION; CELL ISOLATION; CELL PROLIFERATION; CELL PROTECTION; CELL STRESS; CELLULAR STRESS RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; DRUG TARGETING; EMBRYO; EMBRYO CELL; NERVE CELL NECROSIS; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MITOCHONDRION;

ACETYLCARNITINE; ANESTHETICS, INTRAVENOUS; ANIMALS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTASE; MITOCHONDRIA; NEURAL STEM CELLS; NEUROPROTECTIVE AGENTS; PROPOFOL; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, GABA-A;

EID: 84899806534     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.03.011     Document Type: Article

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