Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: Implications for Alzheimer's disease

Journal of Neuroscience Research

Volumn 84, Issue 2, 2006, Pages 398-408

  Abdul, Hafiz Mohmmad ^a,b   Calabrese, Vittorio ^c   Calvani, Menotti ^d   Butterfield, D Allan ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF CATANIA   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

Author keywords

3 nitrotyrosine; A 1 42; Acetyl L carnitine; Alzheimer's disease; Inducible nitric oxide synthase; N(G) monomethyl l arginine; Quercitin; Reactive oxygen species; Zn protoporphyrin IX

Indexed keywords

3 NITROTYROSINE; AMYLOID BETA PROTEIN[1-42]; ANTIOXIDANT; DNA FRAGMENT; GLUTATHIONE; HEAT SHOCK PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LEVACECARNINE; PROTOPORPHYRIN; PROTOPORPHYRIN ZINC; QUERCETIN; REACTIVE OXYGEN METABOLITE;

AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOENERGY; BRAIN CELL; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STATISTICAL ANALYSIS; UPREGULATION; WESTERN BLOTTING;

ACETYLCARNITINE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CEREBRAL CORTEX; DNA FRAGMENTATION; GLUTATHIONE; HEAT-SHOCK PROTEINS; LIPID PEROXIDATION; NEURONS; NEUROPROTECTIVE AGENTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION;

EID: 33746468121     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20877     Document Type: Article

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