High-affinity blockade of voltage-operated skeletal muscle and neuronal sodium channels by halogenated propofol analogues

British Journal of Pharmacology

Volumn 155, Issue 2, 2008, Pages 265-275

  Haeseler, G ^a   Karst, M ^a   Foadi, N ^a   Gudehus, S ^a   Roeder, A ^a   Hecker, H ^a   Dengler, R ^a   Leuwer, M ^b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Local anaesthetics; Propofol analogues; Sodium channels; Voltage operated

Indexed keywords

4 BROMOPROPOFOL; 4 CHLOROPROPOFOL; 4 IODOPROPOFOL; LIDOCAINE; PROPOFOL; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; MEMBRANE DEPOLARIZATION; NERVE CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE;

ANIMALS; CELL LINE; HALOGENS; HUMANS; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; NEURONS; PROPOFOL; RATS; SODIUM CHANNEL BLOCKERS; SODIUM CHANNELS;

EID: 51349169373     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/bjp.2008.255     Document Type: Article

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