Regional and temporal profiles of calpain and caspase-3 activities in postnatal rat brain following repeated propofol administration

Developmental Neuroscience

Volumn 32, Issue 4, 2010, Pages 288-301

  Milanovic, Desanka ^a   Popic, Jelena ^a   Pesic, Vesna ^a   Loncarevic Vasiljkovic, Natasa ^a   Kanazir, Selma ^a   Jevtovic Todorovic, Vesna ^b   Ruzdijic, Sabera ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

Anesthesia induced neurotoxicity; Apoptosis; Neurodegeneration; Poly(ADP ribose) polymerase 1; Protein kinase C; Spectrin; Thalamus

Indexed keywords

ALPHA II SPECTRIN; CALPAIN; CASPASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROPOFOL; PROTEIN KINASE C; SPECTRIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; ENZYME ACTIVITY; GENERAL ANESTHESIA; MALE; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SYNAPSE; THALAMUS; WESTERN BLOTTING; WISTAR RAT;

ANESTHETICS, INTRAVENOUS; ANIMALS; BLOTTING, WESTERN; BRAIN; CALPAIN; CASPASE 3; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; PROPOFOL; RATS; RATS, WISTAR;

EID: 78650516486     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000316970     Document Type: Article

References (39)

1. Loepke AW, Soriano SG: An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function. Anesth Analg 2008;106:1681-1707.
2. Fredriksson A, Ponten E, Gordh T, Eriksson P: Neonatal exposure to a combination of N-methyl-D-aspartate and β-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits. Anesthesiology 2007;107:427-435.
3. Henschel O, Gipson KE, Bordey A: GABA A receptors, anesthetics and anticonvulsants in brain development. CNS Neurol Disord Drug Targets 2008;7:211-224.
4. Bercker S, Bert B, Bittigau P, Felderhoff-Muser U, Buhrer C, Ikonomidou C, Weise M, Kaisers UX, Kerner T: Neurodegeneration in newborn rats following propofol and sevoflurane anesthesia. Neurotox Res 2009;16:140-147.
5. Vutskits L, Gascon E, Tassonyi E, Kiss JZ: Clinically relevant concentrations of propofol but not midazolam alter in vitro denditic development of isolated γ-aminobutiric acidpositive interneurons. Anesthesiology 2005;102:970-976.
6. Cattano D, Young C, Straiko M M W, Olney JW: Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain. Anesth Analg 2008;106:1712-1714.
7. Yon JH, Daniel-Johnson J, Carter LB, Jevtovic-Todorovic V: Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways. Neuroscience 2005;135:815-827.
8. Pesic V, Milanovic D, Tanic N, Popic J, Kanazir S, Jevtovic-Todorovic V, Ruzdijic S: Potential mechanism of cell death in the developing rat brain induced by propofol anesthesia. Int J Dev Neurosci 2009;27:279-287.
9. Wang KK: Calpain and caspase: can you tell the difference? Trends Neurosci 2000;23:20-26.
10. Czogalla A, Sikorski AF: Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells. Cell Mol Life Sci 2005;62:1913-1924.
11. McCollum AT, Nasr P, Estus S: Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death. J Neurochem 2002;82:1208-1220.
12. De Roo M, Klauser P, Briner A, Nikonenko I, Mendez P, Dayer A, Kiss JZ, Muller D, Vutskits L: Anesthetics rapidly promote synaptogenesis during a critical period of brain development. PLoS One 2009;4: e7043.
13. Bjornstrom K, Turina D, Loverock A, Lundgren S, Wijkman M, Lindroth M, Eintrei CH: Characterization of the signal transduction cascade caused by propofol in rat neurons: from the GABA A receptor to the cytoskeleton. J Physiol Pharmacol 2008;59:617-632.
14. Turina D, Loitto VM, Bjornstrom K, Sundqvist T, Eintrei C: Propofol causes neurite retraction in neurons. Br J Anesth 2008;101:374-379.
15. Nakao S, Nagata A, Miyamoto E, Masuzawa M, Murayama T, Shingu K: Inhibitory effect of propofol on ketamine-induced c-Fos expression in the rat posterior cingulated and retrosplenial cortices is mediated by GABAA receptor activation. Acta Anesthesiol Scand 2003;47:284-290.
16. Oscarsson A, Massoumi R, Sjolander A, Eintrei C: Reorganization of actin in neurons after propofol exposure. Acta Anesthesiol Scand 2001;45:1215-1220.
17. Northington FJ, Zelaya ME, O'Riordan DP, Blomgren K, Flock DL, Hagberg H, Ferriero DM, Martin LJ: Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as 'continuum' phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain. Neuroscience 2007;149:822-833.
18. Carloni S, Carnevali A, Cimino M, Balduini W: Extended role of necrotic cell death after hypoxia-ischemia-induced neurodegeneration in the neonatal rat. Neurobiol Dis 2007;27:354-361.
19. Jensen AG, Lindroth M, Sjolander A, Eintrei C: Propofol induces changes in the cytosolyc free calcium concentrations and the cytoskeletal organization of cultured human glial cells and primary embryonic rat brain cells. Anesthesiology 1994;81:1220-1229.
20. Rao A, Craig AM: Signaling between the actin cytoskeleton and the postsynaptic density of dendritic spines. Hippocampus 2000;10:527-541.
21. Gomez RS, Guatimosim C, Gomez MV: Mechanism of action of volatile anesthetics: role of protein kinase C. Cell Mol Neurobiol 2003;23:877-885.
22. Shea TB, Cressman CM, Spencer MJ, Beermann ML, Nixon RA: Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C. J Neurochem 1995;65:517-527.
23. Buki KG, Bauer PI, Kun E: Isolation and identification of a proteinase from calf thymus that cleaves poly (ADP-ribose) polymerase and histone H1. Biochim Biophys Acta 1997;1338:100-106.
24. Shah GM, Shah RG, Poirier GG: Different cleavage pattern for poly (ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells. Biochem Biophys Res Commun 1996;229:838-844.
25. Chiarugi A: Poly (ADP-ribose) polymerase: killer or conspirator? The 'suicide hypothesis' revisited. Trends Pharmacol Sci 2002;23:122-129.
26. Visochek L, Steingart RA, Vulih-Shultzman I, Klein R, Priel E, Gozes I, Cohen-Armon M: PolyADP-rybosylation is involved in neurotrophic activity. J Neurosci 2005;25:7420-7428.
27. Tanaka Y, Koide S, Yoshihara K, Kamiya T: Poly (ADP-ribose) synthetase is phosphorylated by protein kinase C in vitro. Biochem Biophys Res Commun 1987;148:709-717.
28. Nicolas G, Fournier CM, Galand C, Malbert-Colas L, Bournier O, Kroviarski Y, Bourgeois M, Camonis JH, Dhermy D, Grandchamp B, Lecomte MC: Tyrosine phosphorylation regulates alpha II spectrin cleavage by calpain. Molec Cell Biol 2002;22:3527-3536.
29. Ikonomidou C, Bittigau P, Ishimaru MJ, Wozniak DF, Koch C, Genz K, Tenkova TI, Stefanovska V, Horster F, Tenkova T, Dikranian K, Olney JW: Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 2000;283:1056-1060. (Pubitemid 30094364)
30. Heaton MB, Paiva M, Madorsky I, Shaw G: Ethanol effects on neonatal rat cortex: comparative analyses of neurotrophic factors, apoptosis-related proteins, and oxidative processes during vulnerable and resistant periods. Dev Brain Res 2003;145:249-262.
31. Kahraman S, Zup SL, McCarthy MM, Fiskum G: GABAergic mechanisms of propofol toxicity in immature neurons. Neurosurg Anesthesiol 2008;20:233-240.
32. McLaughlin B: The kinder side of killer proteases: caspase activation contributes to neuroprotection and CNS remodeling. Apoptosis 2004;9:111-121.
33. Villapol S, Acarin L, Faiz M, Castellano B, Gonzales B: Survivin and heat shock protein 25/75 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain. Neuroscience 2008;153:108-119.
34. Acarin L, Villapol S, Faiz M, Rohn TT, Castellano B: Caspase-3 activation in astrocytes following postnatal excitotoxic damage correlates with cytoskeletal remodeling but not with cell death or proliferation. Glia 2007;55:954-965.
35. Bazin JE, Constantin JM, Gindre G: Laboratory animal anesthesia: influence of anesthetic protocols on experimental models. Ann Fr Anesth Reanim 2004;23:811-818.
36. Anand K J S, Coskun V, Thrivikraman KV, Nemeroff CB, Plotsky PM: Long-term behavioral effects of repetitive pain in neonatal rat pups. Physiol Behav 1999;66:627-637.
37. Anand K J S, Garg S, Rovnaghi CR, Narsinghani U, Bhutta AT, Hall RW: Ketamine reduces the cell death following inflammatory pain in newborn rat brain. Pediatr Res 2007;62:283-290.
38. Yang H, Liang G, Hawkins B, Madesh M, Pierwola A, Wei H: Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies. Anesthesiology 2008;109:243-250.
39. Zhang G, Dong Y, Zhang B, Ichinose F, Wu X, Culley D J, Crosby G, Tanzi RE, Xie Z: Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine. J Neurosci 2008;