Metformin ameliorates ovariectomy-induced vascular dysfunction in non-diabetic wistar rats

Clinical Science

Volumn 127, Issue 4, 2014, Pages 265-275

  Oliveira, Phablo Wendell C ^a   de Sousa, Glauciene J ^a   Caliman, Izabela F ^a   Lamas, Aline Z ^a   Santos de Medeiros, Ana Raquel ^b   de Andrade, Tadeu U ^a,c   de Abreu, Glaucia R ^a   de Figueiredo, Suely G ^a   Bissoli, Nazaré S ^a  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^b INSTITUTO FEDERAL DO ESPÍRITO SANTO   (Brazil)

^c UNIVERSIDADE VILA VELHA   (Brazil)

Author keywords

Mesenteric bed; Metformin; Nitric oxide; Ovariectomy; Oxidative stress; Vascular dysfunction

Indexed keywords

4 AMINOPYRIDINE; ACETYLCHOLINE; APOCYNIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ESTRADIOL; GLUCOSE; METFORMIN; NITROPRUSSIDE SODIUM; PROGESTERONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CONTROLLED STUDY; DIET RESTRICTION; DRUG EFFECT; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESTRADIOL BLOOD LEVEL; ESTRUS CYCLE; FEMALE; GLUCOSE BLOOD LEVEL; MESENTERY BLOOD FLOW; NONHUMAN; OVARIECTOMY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; TREATMENT DURATION; UTERUS WEIGHT; VASCULAR DISEASE; VASOCONSTRICTION; VASODILATATION; WEIGHT GAIN; WESTERN BLOTTING;

ACETYLCHOLINE; ANIMALS; ENDOTHELIUM, VASCULAR; FEMALE; HYPOGLYCEMIC AGENTS; MEMBRANE GLYCOPROTEINS; METFORMIN; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; OVARIECTOMY; RATS; RATS, WISTAR; VASCULAR DISEASES; VASODILATION;

EID: 84899784309     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20130553     Document Type: Article

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