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Volumn 28, Issue 4, 2007, Pages 555-560

Metformin restores the penile expression of nitric oxide synthase in high-fat-fed obese rats

Author keywords

AMP activated protein kinase; Penile tissue

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; METFORMIN; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE;

EID: 34447320747     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: 10.2164/jandrol.106.001602     Document Type: Article
Times cited : (37)

References (30)
  • 1
    • 0037810808 scopus 로고    scopus 로고
    • Erectile physiological and pathophysiological pathway involved in erectile dysfunction
    • Andersson KE. Erectile physiological and pathophysiological pathway involved in erectile dysfunction. J Urol. 2003;170:S6-S14.
    • (2003) J Urol , vol.170
    • Andersson, K.E.1
  • 3
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium-thiocyanate-phenolchloroform extraction
    • Chromczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium-thiocyanate-phenolchloroform extraction. Anal Biochem. 1987;162:156-159.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chromczynski, P.1    Sacchi, N.2
  • 4
    • 33644747421 scopus 로고    scopus 로고
    • Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthase in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase
    • Davis BJ, Xie Z, Viollet B, Zou MH. Activation of the AMP-activated kinase by antidiabetes drug metformin stimulates nitric oxide synthase in vivo by promoting the association of heat shock protein 90 and endothelial nitric oxide synthase. Diabetes. 2006;55:496-505.
    • (2006) Diabetes , vol.55 , pp. 496-505
    • Davis, B.J.1    Xie, Z.2    Viollet, B.3    Zou, M.H.4
  • 6
    • 29544435525 scopus 로고    scopus 로고
    • Endothelial dysfunction, diabetes mellitus, and the metabolic syndrome: Common pathways and treatments?
    • Fonseca V, Jawa A. Endothelial dysfunction, diabetes mellitus, and the metabolic syndrome: common pathways and treatments? Am J Cardiol. 2005;96:13M-18M.
    • (2005) Am J Cardiol , vol.96
    • Fonseca, V.1    Jawa, A.2
  • 7
    • 0033664017 scopus 로고    scopus 로고
    • Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase
    • Fryer LG, Hajduch E, Rencurel F, Salt IP, Hundal HS, Hardie DG, Carling D. Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase. Diabetes. 2000;49:1978-1985.
    • (2000) Diabetes , vol.49 , pp. 1978-1985
    • Fryer, L.G.1    Hajduch, E.2    Rencurel, F.3    Salt, I.P.4    Hundal, H.S.5    Hardie, D.G.6    Carling, D.7
  • 8
    • 0037067666 scopus 로고    scopus 로고
    • The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways
    • Fryer LG, Parbu-Patel A, Carling D. The anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways. J Biol Chem. 2002;277:25226-25232.
    • (2002) J Biol Chem , vol.277 , pp. 25226-25232
    • Fryer, L.G.1    Parbu-Patel, A.2    Carling, D.3
  • 10
    • 0031007065 scopus 로고    scopus 로고
    • The AMP-activated protein kinase-fuel gauge of the mammalian cells?
    • Hardie DG, Carling D. The AMP-activated protein kinase-fuel gauge of the mammalian cells? Eur J Biochem. 1997;246:259-273.
    • (1997) Eur J Biochem , vol.246 , pp. 259-273
    • Hardie, D.G.1    Carling, D.2
  • 11
    • 0036324142 scopus 로고    scopus 로고
    • The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
    • Hawley SA, Gadalla AE, Olsen GS, Hardie DG. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes. 2002;51:2420-2425.
    • (2002) Diabetes , vol.51 , pp. 2420-2425
    • Hawley, S.A.1    Gadalla, A.E.2    Olsen, G.S.3    Hardie, D.G.4
  • 12
    • 0026801474 scopus 로고
    • Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells
    • Hundal HG, Ramlal T, Reyes R, Leiter LA. Cellular mechanism of metformin action involves glucose transporter translocation from an intracellular pool to the plasma membrane in L6 muscle cells. Endocrinology. 1992;131:1165-1173.
    • (1992) Endocrinology , vol.131 , pp. 1165-1173
    • Hundal, H.G.1    Ramlal, T.2    Reyes, R.3    Leiter, L.A.4
  • 18
    • 32844463192 scopus 로고    scopus 로고
    • Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin
    • Li Z. Rodriguez-Iturbe B, Ni Z, Shahkarami A, Sepassi L, Vaziri ND. Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin. Kidney Int. 2005;68:2766-2772.
    • (2005) Kidney Int , vol.68 , pp. 2766-2772
    • Li, Z.1    Rodriguez-Iturbe, B.2    Ni, Z.3    Shahkarami, A.4    Sepassi, L.5    Vaziri, N.D.6
  • 19
    • 28444497837 scopus 로고    scopus 로고
    • High-fat diet feeding impairs both the expression and activity of AMPKα in rats' skeletal muscle
    • Liu Y, Wan Q, Guan Q, Gao L, Zhao J. High-fat diet feeding impairs both the expression and activity of AMPKα in rats' skeletal muscle. Biochem Biophys Res Commun. 2006;339:701-707.
    • (2006) Biochem Biophys Res Commun , vol.339 , pp. 701-707
    • Liu, Y.1    Wan, Q.2    Guan, Q.3    Gao, L.4    Zhao, J.5
  • 20
    • 0029893203 scopus 로고    scopus 로고
    • Nitric oxide synthase levels in obese Zucker rats
    • Morley JE, Mattammal MB. Nitric oxide synthase levels in obese Zucker rats. Neurosci Lett. 1996;209:137-139.
    • (1996) Neurosci Lett , vol.209 , pp. 137-139
    • Morley, J.E.1    Mattammal, M.B.2
  • 21
    • 0041355355 scopus 로고    scopus 로고
    • Direct activation of AMP-activated protein kinase stimulates nitric oxide synthesis in human aortic endothelial cells
    • Morrow VA, Foufelle F, Connell JM, Petrie JR, Gould GW, Salt IP. Direct activation of AMP-activated protein kinase stimulates nitric oxide synthesis in human aortic endothelial cells. J Biol Chem. 2003;278:31629-31639.
    • (2003) J Biol Chem , vol.278 , pp. 31629-31639
    • Morrow, V.A.1    Foufelle, F.2    Connell, J.M.3    Petrie, J.R.4    Gould, G.W.5    Salt, I.P.6
  • 22
    • 19744372761 scopus 로고    scopus 로고
    • Age-related changes in phosphorylation of endothelial nitric oxide synthase in the rat penis
    • Musicki B, Kramer MF, Becker RE, Burnett AL. Age-related changes in phosphorylation of endothelial nitric oxide synthase in the rat penis. J Sex Med. 2005;2:347-355.
    • (2005) J Sex Med , vol.2 , pp. 347-355
    • Musicki, B.1    Kramer, M.F.2    Becker, R.E.3    Burnett, A.L.4
  • 23
    • 0032565971 scopus 로고    scopus 로고
    • Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome
    • Nestler JE, Jakubowicz DJ, Evans WS, Pasquali R. Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome. N Engl J Med. 1998;338:1876-1880.
    • (1998) N Engl J Med , vol.338 , pp. 1876-1880
    • Nestler, J.E.1    Jakubowicz, D.J.2    Evans, W.S.3    Pasquali, R.4
  • 25
    • 11144313175 scopus 로고    scopus 로고
    • A high fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression
    • Roberts CK, Barnard RJ, Sindhu RK, Jurczak M, Ehdaie A, Vaziri ND. A high fat, refined-carbohydrate diet induces endothelial dysfunction and oxidant/antioxidant imbalance and depresses NOS protein expression. J Appl Physiol. 2005;98:203-210.
    • (2005) J Appl Physiol , vol.98 , pp. 203-210
    • Roberts, C.K.1    Barnard, R.J.2    Sindhu, R.K.3    Jurczak, M.4    Ehdaie, A.5    Vaziri, N.D.6
  • 26
    • 24344454347 scopus 로고    scopus 로고
    • Metformin treatment restores the altered microvascular reactivity in neonatal streptozotocin-induced diabetic rats increasing NOS activity, but not NOS expression
    • Sartoretto JL, Melo GAN, Carvalho MHC, Nigro D, Passaglia RT, Scavone C, Cuman RKN, Fortes ZB. Metformin treatment restores the altered microvascular reactivity in neonatal streptozotocin-induced diabetic rats increasing NOS activity, but not NOS expression. Life Sci. 2005;77:2676-2689.
    • (2005) Life Sci , vol.77 , pp. 2676-2689
    • Sartoretto, J.L.1    Melo, G.A.N.2    Carvalho, M.H.C.3    Nigro, D.4    Passaglia, R.T.5    Scavone, C.6    Cuman, R.K.N.7    Fortes, Z.B.8
  • 28
    • 0032697674 scopus 로고    scopus 로고
    • The antihyperglycemic effect of metformin: Therapeutic and cellular mechanisms
    • Wiernsperger NF, Bailey CJ. The antihyperglycemic effect of metformin: therapeutic and cellular mechanisms. Drugs. 1999;58:31-39.
    • (1999) Drugs , vol.58 , pp. 31-39
    • Wiernsperger, N.F.1    Bailey, C.J.2
  • 29
    • 33646032996 scopus 로고    scopus 로고
    • Erectile potentials of a new phosphodiesterase type 5 inhibitor, DA-8159, in diet-induced obese rats
    • Yu JY, Kang KK, Yoo M. Erectile potentials of a new phosphodiesterase type 5 inhibitor, DA-8159, in diet-induced obese rats. Asian J Androl. 2006;8:325-329.
    • (2006) Asian J Androl , vol.8 , pp. 325-329
    • Yu, J.Y.1    Kang, K.K.2    Yoo, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.