Endothelial function is impaired across the stages of the menopause transition in healthy women

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 12, 2012, Pages 4692-4700

  Moreau, Kerrie L ^a   Hildreth, Kerry L ^a   Meditz, Amie L ^a   Deane, Kevin D ^b   Kohrt, Wendy M ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SEX HORMONE;

ADULT; AGED; ARTERY BLOOD FLOW; ARTICLE; BRONCHIAL ARTERY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLIMACTERIUM; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISEASE COURSE; ECHOGRAPHY; ENDOTHELIAL DYSFUNCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MENOPAUSE RELATED DISORDER; POSTMENOPAUSE; PREDICTION; PREMENOPAUSE; PRIORITY JOURNAL; VASCULAR ENDOTHELIUM; VASODILATATION; VASOMOTOR DISORDER;

ADULT; AGED; BRACHIAL ARTERY; CARDIOVASCULAR DISEASES; COHORT STUDIES; CROSS-SECTIONAL STUDIES; ENDOTHELIUM, VASCULAR; FEMALE; HEALTH; HUMANS; MENOPAUSE; MIDDLE AGED; RISK FACTORS; VASODILATION; WOMEN'S HEALTH; YOUNG ADULT;

EID: 84870760671     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2012-2244     Document Type: Article

References (40)

1. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB 2012 Executive Summary: heart disease and stroke statistics - 2012 update. Circulation 125:188-197
2. Manson JE, Hsia J, Johnson KC, Rossouw JE, Assaf AR, Lasser NL, Trevisan M, Black HR, Heckbert SR, Detrano R, Strickland OL, Wong ND, Crouse JR, Stein E, Cushman M 2003 Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 349:523-534 (Pubitemid 36951364)
3. Anderson GL, Limacher M, Assaf AR, Bassford T, Beresford SA, Black H, Bonds D, Brunner R, Brzyski R, Caan B, Chlebowski R, Curb D, Gass M, Hays J, Heiss G, Hendrix S, Howard BV, Hsia J, Hubbell A, Jackson R, Johnson KC, Judd H, Kotchen JM, Kuller L, LaCroix AZ, Lane D, Langer RD, Lasser N, Lewis CE, Manson J, Margolis K, Ockene J, O'Sullivan MJ, Phillips L, Prentice RL, Ritenbaugh C, Robbins J, Rossouw JE, Sarto G, Stefanick ML, Van Horn L, Wactawski-Wende J, Wallace R, Wassertheil-Smoller S 2004 Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA 291:1701-1712 (Pubitemid 38489892)
4. Clarkson TB 2007 Estrogen effects on arteries vary with stage of reproductive life and extent of subclinical atherosclerosis progression. Menopause 14:373-384
5. Lakatta EG, Levy D 2003 Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation 107:139-146 (Pubitemid 36070946)
6. Rossi R, Nuzzo A, Origliani G, Modena MG 2008 Prognostic role of flow-mediated dilation and cardiac risk factors in post-menopausal women. J Am Coll Cardiol 51:997-1002 (Pubitemid 351318128)
7. Thurston RC, Sutton-Tyrrell K, Everson-Rose SA, Hess R, Matthews KA 2008 Hot flashes and subclinical cardiovascular disease. Circulation 118:1234-1240
8. Bechlioulis A, Kalantaridou SN, Naka KK, Chatzikyriakidou A, Calis KA, Makrigiannakis A, Papanikolaou O, Kaponis A, Katsouras C, Georgiou I, Chrousos GP, Michalis LK 2010 Endothelial function, but not carotid intima-media thickness, is affected early in menopause and is associated with severity of hot flushes. J Clin Endocrinol Metab 95:1199-1206
9. Matthews KA, Crawford SL, Chae CU, Everson-Rose SA, Sowers MF, Sternfeld B, Sutton-Tyrrell K 2009 Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition? J Am Coll Cardiol 54:2366-2373
10. Wildman RP, Colvin AB, Powell LH, Matthews KA, Everson-Rose SA, Hollenberg S, Johnston JM, Sutton-Tyrrell K 2008 Associations of endogenous sex hormones with the vasculature in menopausal women: the Study of Women's Health Across the Nation (SWAN). Menopause 15:414-421 (Pubitemid 351656744)
11. Celermajer DS, Sorensen KE, Spiegelhalter DJ, Georgakopoulos D, Robinson J, Deanfield JE 1994 Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women. J Am Coll Cardiol 24:471-476 (Pubitemid 24246550)
12. Taddei S, Virdis A, Ghiadoni L, Mattei P, Sudano I, Bernini G, Pinto S, Salvetti A 1996 Menopause is associated with endothelial dysfunction in women. Hypertension 28:576-582 (Pubitemid 26327952)
13. Soules MR, Sherman S, Parrott E, Rebar R, Santoro N, Utian W, Woods N 2001 Stages of Reproductive Aging Workshop (STRAW). J Womens Health Gend Based Med 10:843-848 (Pubitemid 33138765)
14. Moreau KL, Meditz A, Deane KD, Kohrt WM 2012 Tetrahydrobiopterin improves endothelial function and decreases arterial stiffness in estrogen-deficient postmenopausal women. Am J Physiol Heart Circ Physiol 302:H1211-H1218
15. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, Herrington D, Vallance P, Vita J, Vogel R 2002 Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39:257-265 (Pubitemid 34084631)
16. Eskurza I, Monahan KD, Robinson JA, Seals DR 2004 Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol 556:315-324 (Pubitemid 38519054)
17. Tanaka H, Dinenno FA, Monahan KD, Clevenger CM, DeSouza CA, Seals DR 2000 Aging, habitual exercise, and dynamic arterial compliance. Circulation 102:1270-1275
18. Lohman TG, Roche AF, Martorell R 1988 Anthropometric standardization reference manual. Champaign, IL: Human Kinetics
19. Tanaka H, Desouza CA, Jones PP, Stevenson ET, Davy KP, Seals DR 1997 Greater rate of decline in maximal aerobic capacity with age in physically active vs. sedentary healthy women. J Appl Physiol 83:1947-1953 (Pubitemid 28006495)
20. Pereira MA, FitzerGerald SJ, Gregg EW, Joswiak ML, Ryan WJ, Suminski RR, Utter AC, Zmuda JM 1997 A collection of physical activity questionnaires for health-related research. Med Sci Sports Exerc 29:S1-205
21. Friedewald WT, Levey RI, Frederickson DS 1972 Estimation of the concentration of LDL-Cin plasma without the use of the preparative ultracentrifuge. Clin Chem 18:499-502
22. Gavin KM, Jankowski CM, Kohrt WM, Stauffer BL, Seals DR, Moreau KL Hysterectomy is associated with large artery stiffening in estrogen-deficient postmenopausal women. Menopause 19:1000-1007
23. Moreau KL, Gavin KM, Plum AE, Seals DR 2006 Oxidative stress explains differences in large elastic artery compliance between sedentary and habitually exercising postmenopausal women. Menopause 13:951-958 (Pubitemid 44760388)
24. Perz JM 1997 Development of the menopause symptom list: a factor analytic study of menopause associated symptoms. Women Health 25:53-69 (Pubitemid 27373042)
25. Kalantaridou SN, Naka KK, Papanikolaou E, Kazakos N, Kravariti M, Calis KA, Paraskevaidis EA, Sideris DA, Tsatsoulis A, Chrousos GP, Michalis LK 2004 Impaired endothelial function in young women with premature ovarian failure: normalization with hormone therapy. J Clin Endocrinol Metab 89:3907-3913 (Pubitemid 39071493)
26. Solomon CG, Hu FB, Dunaif A, Rich-Edwards JE, Stampfer MJ, Willett WC, Speizer FE, Manson JE 2002 Menstrual cycle irregularity and risk for future cardiovascular disease. J Clin Endocrinol Metab 87:2013-2017 (Pubitemid 34521483)
27. Matthews KA, Kuller LH, Sutton-Tyrrell K, Chang YF 2001 Changes in cardiovascular risk factors during the perimenopause and postmenopause and carotid artery atherosclerosis in healthy women. Stroke 32:1104-1111
28. Bourque SL, Davidge ST, Adams MA 2011 The interaction between endothelin-1 and nitric oxide in the vasculature: new perspectives. Am J Physiol Regul Integr Comp Physiol 300:R1288-R1295
29. Zanzinger J, Czachurski J, Seller H 1994 Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo. Circ Res 75:1073-1077 (Pubitemid 24351452)
30. Mendelsohn ME 2000 Mechanisms of estrogen action in the cardiovascular system. J Steroid Biochem Mol Biol 74:337-343 (Pubitemid 32140406)
31. Sudhir K, Ko E, Zellner C, Wong HE, Hutchison SJ, Chou TM, Chatterjee K 1997 Physiological concentrations of estradiol attenuate endothelin 1-induced coronary vasoconstriction in vivo. Circulation 96:3626-3632 (Pubitemid 27513442)
32. Sudhir K, Elser MD, Jennings GL, Komesaroff PA 1997 Estrogen supplementation decreases norepinephrine-induced vasoconstriction and total body norepinephrine spillover in perimenopausal women. Hypertension 30:1538-1543 (Pubitemid 27528101)
33. Kaplon RE, Walker AE, Seals DR 2011 Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women. J Appl Physiol 111:1416-1421
34. Gavin KM, Seals DR, Silver AE, Moreau KL 2009 Vascular endothelial estrogen receptor α is modulated by estrogen status and related to endothelial function and endothelial nitric oxide synthase in healthy women. J Clin Endocrinol Metab 94:3513-3520
35. Hale GE, Zhao X, Hughes CL, Burger HG, Robertson DM, Fraser IS 2007 Endocrine features of menstrual cycles in middle and late reproductive age and the menopausal transition classified according to the Staging of Reproductive Aging Workshop (STRAW) staging system. J Clin Endocrinol Metab 92:3060-3067 (Pubitemid 47236371)
36. Randolph Jr JF, Zheng H, Sowers MR, Crandall C, Crawford S, Gold EB, Vuga M 2011 Change in follicle-stimulating hormone and estradiol across the menopausal transition: effect of age at the final menstrual period. J Clin Endocrinol Metab 96:746-754
37. Sowers MR, Zheng H, McConnell D, Nan B, Harlow SD, Randolph Jr JF 2008 Estradiol rates of change in relation to the final menstrual period in a population-based cohort of women. J Clin Endocrinol Metab 93:3847-3852
38. Harlow SD, Gass M, Hall JE, Lobo R, Maki P, Rebar RW, Sherman S, Sluss PM, de Villiers TJ, for the SCG 2012 Executive summary of the Stages of Reproductive Aging Workshop + 10: addressing the unfinished agenda of staging reproductive aging. Menopause 19:387-395
39. Strong JP, Malcom GT, McMahan CA, Tracy RE, Newman 3rd WP, Herderick EE, Cornhill JF 1999 Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study. JAMA 281:727-735 (Pubitemid 29113454)
40. Santoro N, Sutton-Tyrrell K 2011 The SWAN song: Study of Women's Health Across the Nation's recurring themes. Obstet Gynecol Clin North Am 38:417-423