-
2
-
-
0035554898
-
Multiple sclerosis: A two-stage disease
-
Steinman L. Multiple sclerosis: a two-stage disease. Nat Immunol. 2001;2(9):762-764.
-
(2001)
Nat Immunol.
, vol.2
, Issue.9
, pp. 762-764
-
-
Steinman, L.1
-
3
-
-
0028221166
-
Animal models for multiple sclerosis
-
Wekerle H, Kojima K, Lannes-Vieira J, Lassmann H, Linington C. Animal models for multiple sclerosis. Ann Neurol. 1994;36(suppl):S47-S53.
-
(1994)
Ann Neurol.
, vol.36
, Issue.SUPPL.
-
-
Wekerle, H.1
Kojima, K.2
Lannes-Vieira, J.3
Lassmann, H.4
Linington, C.5
-
4
-
-
0025787089
-
Multiple sclerosis: A pivotal role for the T cell in lesion development
-
Raine CS. Multiple sclerosis: a pivotal role for the T cell in lesion development. Neuropathol Appl Neurobiol. 1991;17(4):265-274.
-
(1991)
Neuropathol Appl Neurobiol.
, vol.17
, Issue.4
, pp. 265-274
-
-
Raine, C.S.1
-
5
-
-
42249084849
-
Either a Th17 or a Th1 effector response can drive autoimmunity: Conditions of disease induction affect dominant effector category
-
Luger D, et al. Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category. J Exp Med. 2008;205(4):799-810.
-
(2008)
J Exp Med.
, vol.205
, Issue.4
, pp. 799-810
-
-
Luger, D.1
-
6
-
-
13244290058
-
IL-12- and IL-23-induced T helper cell subsets: Birds of the same feather flock together
-
Bettelli E, Kuchroo VK. IL-12- and IL-23-induced T helper cell subsets: birds of the same feather flock together. J Exp Med. 2005;201(2):169-171.
-
(2005)
J Exp Med.
, vol.201
, Issue.2
, pp. 169-171
-
-
Bettelli, E.1
Kuchroo, V.K.2
-
7
-
-
0037434789
-
Interleukin-23 rather than interleukin- 12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua DJ, et al. Interleukin-23 rather than interleukin- 12 is the critical cytokine for autoimmune inflammation of the brain. Nature. 2003;421(6924):744- 748.
-
(2003)
Nature
, vol.421
, Issue.6924
, pp. 744-748
-
-
Cua, D.J.1
-
8
-
-
33846966636
-
A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage
-
Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat Med. 2007; 13(2):139-145.
-
(2007)
Nat Med.
, vol.13
, Issue.2
, pp. 139-145
-
-
Steinman, L.1
-
9
-
-
77953210389
-
Antigen-specific CD25- Foxp3- IFN-(high) CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17
-
Wildbaum G, Zohar Y, Karin N. Antigen-specific CD25- Foxp3- IFN-(high) CD4+ T cells restrain the development of experimental allergic encephalomyelitis by suppressing Th17. Am J Pathol. 2010;176(6):2764-2775.
-
(2010)
Am J Pathol.
, vol.176
, Issue.6
, pp. 2764-2775
-
-
Wildbaum, G.1
Zohar, Y.2
Karin, N.3
-
10
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol. 2005; 6(4):345-352.
-
(2005)
Nat Immunol.
, vol.6
, Issue.4
, pp. 345-352
-
-
Sakaguchi, S.1
-
11
-
-
65549136983
-
Mechanisms of foxp3+ T regulatory cell-mediated suppression
-
Shevach EM. Mechanisms of foxp3+ T regulatory cell-mediated suppression. Immunity. 2009; 30(5):636-645.
-
(2009)
Immunity.
, vol.30
, Issue.5
, pp. 636-645
-
-
Shevach, E.M.1
-
12
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen- specific T-cell responses and prevents colitis
-
Groux H, et al. A CD4+ T-cell subset inhibits antigen- specific T-cell responses and prevents colitis. Nature. 1997;389(6652):737-742.
-
(1997)
Nature
, vol.389
, Issue.6652
, pp. 737-742
-
-
Groux, H.1
-
13
-
-
0028037782
-
Regulatory T-cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen Y, Kuchroo VK, Inobe J, Hafler D, Weiner HL. Regulatory T-cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science. 1994;265(5176):1237-1240.
-
(1994)
Science.
, vol.265
, Issue.5176
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.4
Weiner, H.L.5
-
14
-
-
0034144269
-
Chemokines: A new clasification system and their role in immunity
-
Zlotnic A, Yoshei O. Chemokines: A new clasification system and their role in immunity. Immunity. 2000;12(2):121-127.
-
(2000)
Immunity.
, vol.12
, Issue.2
, pp. 121-127
-
-
Zlotnic, A.1
Yoshei, O.2
-
15
-
-
0036485214
-
Chemokine receptors: A multifaceted therapeutic targets
-
Proudfoot AE. chemokine receptors: A multifaceted therapeutic targets. Nat Rev Immunol. 2002; 2(2):106-115.
-
(2002)
Nat Rev Immunol.
, vol.2
, Issue.2
, pp. 106-115
-
-
Proudfoot, A.E.1
-
16
-
-
0032509889
-
Chemokines - Chemotactic cytokines that mediate inflammation
-
Luster AD. Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med. 1998; 338(7):436-445.
-
(1998)
N Engl J Med.
, vol.338
, Issue.7
, pp. 436-445
-
-
Luster, A.D.1
-
17
-
-
84862776738
-
Biased signaling pathways in 2-adrenergic receptor characterized by 19F-NMR
-
Liu JJ, Horst R, Katritch V, Stevens RC, Wuthrich K. Biased signaling pathways in 2-adrenergic receptor characterized by 19F-NMR. Science. 2012; 335(6072):1106-1110.
-
(2012)
Science.
, vol.335
, Issue.6072
, pp. 1106-1110
-
-
Liu, J.J.1
Horst, R.2
Katritch, V.3
Stevens, R.C.4
Wuthrich, K.5
-
18
-
-
84862895073
-
A biased ligand for OXE-R uncouples G and G signaling within a heterotrimer
-
Blattermann S, et al. A biased ligand for OXE-R uncouples G and G signaling within a heterotrimer. Nat Chem Biol. 2012;8(7):631-638.
-
(2012)
Nat Chem Biol.
, vol.8
, Issue.7
, pp. 631-638
-
-
Blattermann, S.1
-
19
-
-
76249134336
-
Arrestin- but not G proteinmediated signaling by the "decoy" receptor CXCR7
-
Rajagopal S, et al. Arrestin- but not G proteinmediated signaling by the "decoy" receptor CXCR7. Proc Natl Acad Sci U S A. 2010;107(2):628-632.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, Issue.2
, pp. 628-632
-
-
Rajagopal, S.1
-
21
-
-
84860253205
-
Differential arrestindependent conformational signaling and cellular responses revealed by angiotensin analogs
-
Zimmerman B, et al. Differential arrestindependent conformational signaling and cellular responses revealed by angiotensin analogs. Sci Signal. 2012;5(221):ra33.
-
(2012)
Sci Signal.
, vol.5
, Issue.221
-
-
Zimmerman, B.1
-
22
-
-
0038796251
-
A mutated CCR5 gene may have favorable prognostic implications in MS
-
Kantor R, Bakhanashvili M, Achiron A. A mutated CCR5 gene may have favorable prognostic implications in MS. Neurology. 2003;61(2):238-240.
-
(2003)
Neurology.
, vol.61
, Issue.2
, pp. 238-240
-
-
Kantor, R.1
Bakhanashvili, M.2
Achiron, A.3
-
23
-
-
0035478591
-
Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis
-
Liu MT, Keirstead HS, Lane TE. Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis. J Immunol. 2001;167(7):4091- 4097.
-
(2001)
J Immunol.
, vol.167
, Issue.7
, pp. 4091-4097
-
-
Liu, M.T.1
Keirstead, H.S.2
Lane, T.E.3
-
24
-
-
0035253737
-
Expression of Mig (monokine induced by interferon) is important in T lymphocyte recruitment and host defense following viral infection of the central nervous system
-
Liu MT, Armstrong D, Hamilton TA, Lane TE. Expression of Mig (monokine induced by interferon) is important in T lymphocyte recruitment and host defense following viral infection of the central nervous system. J Immunol. 2001; 166(3):1790-1795.
-
(2001)
J Immunol.
, vol.166
, Issue.3
, pp. 1790-1795
-
-
Liu, M.T.1
Armstrong, D.2
Hamilton, T.A.3
Lane, T.E.4
-
25
-
-
0142259710
-
Three or more routes for leukocyte migration into the central nervous system
-
Ransohoff RM, Kivisakk P, Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat Rev Immunol. 2003;3(7):569-581.
-
(2003)
Nat Rev Immunol.
, vol.3
, Issue.7
, pp. 569-581
-
-
Ransohoff, R.M.1
Kivisakk, P.2
Kidd, G.3
-
26
-
-
0033849381
-
Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent
-
Rottman JB, Slavin AJ, Silva R, Weiner HL, Gerard CG, Hancock WW. Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent. Eur J Immunol. 2000; 30(8):2372-2377.
-
(2000)
Eur J Immunol.
, vol.30
, Issue.8
, pp. 2372-2377
-
-
Rottman, J.B.1
Slavin, A.J.2
Silva, R.3
Weiner, H.L.4
Gerard, C.G.5
Hancock, W.W.6
-
27
-
-
0033559346
-
Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
-
Sorensen TL, et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J Clin Invest. 1999;103(6):807-815.
-
(1999)
J Clin Invest.
, vol.103
, Issue.6
, pp. 807-815
-
-
Sorensen, T.L.1
-
28
-
-
0033536062
-
CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions
-
Balashov KE, Rottman JB, Weiner HL, Hancock WW. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions. Proc Natl Acad Sci U S A. 1999;96(12):6873-6878.
-
(1999)
Proc Natl Acad Sci U S A.
, vol.96
, Issue.12
, pp. 6873-6878
-
-
Balashov, K.E.1
Rottman, J.B.2
Weiner, H.L.3
Hancock, W.W.4
-
29
-
-
0033646462
-
Chemokines and chemokine receptors in inflammation of the nervous system: Manifold roles and exquisite regulation
-
Huang D, et al. Chemokines and chemokine receptors in inflammation of the nervous system: manifold roles and exquisite regulation. Immunol Rev. 2000;177:52-67.
-
(2000)
Immunol Rev.
, vol.177
, pp. 52-67
-
-
Huang, D.1
-
30
-
-
0035911254
-
Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
-
Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med. 2001;193(6):713-726.
-
(2001)
J Exp Med.
, vol.193
, Issue.6
, pp. 713-726
-
-
Huang, D.R.1
Wang, J.2
Kivisakk, P.3
Rollins, B.J.4
Ransohoff, R.M.5
-
31
-
-
0029015342
-
Chemokine expression in murine experimental allergic encephalomyelitis
-
Godiska R, Chantry D, Dietsch GN, Gray PW. Chemokine expression in murine experimental allergic encephalomyelitis. J Neuroimmunol. 1995; 58(2):167-176.
-
(1995)
J Neuroimmunol.
, vol.58
, Issue.2
, pp. 167-176
-
-
Godiska, R.1
Chantry, D.2
Dietsch, G.N.3
Gray, P.W.4
-
32
-
-
0034596949
-
Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
-
Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med. 2000;192(7):1075-1080.
-
(2000)
J Exp Med.
, vol.192
, Issue.7
, pp. 1075-1080
-
-
Izikson, L.1
Klein, R.S.2
Charo, I.F.3
Weiner, H.L.4
Luster, A.D.5
-
33
-
-
0035874640
-
CXCL10 (IFN-/-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis
-
Fife BT, et al. CXCL10 (IFN-/-inducible protein-10) control of encephalitogenic CD4+ T cell accumulation in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2001;166(12):7617-7624.
-
(2001)
J Immunol.
, vol.166
, Issue.12
, pp. 7617-7624
-
-
Fife, B.T.1
-
34
-
-
0035889488
-
Selective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis
-
Fife BT, Paniagua MC, Lukacs NW, Kunkel SL, Karpus WJ. Selective CC chemokine receptor expression by central nervous system-infiltrating encephalitogenic T cells during experimental autoimmune encephalomyelitis. J Neurosci Res. 2001;66(4):705-714.
-
(2001)
J Neurosci Res.
, vol.66
, Issue.4
, pp. 705-714
-
-
Fife, B.T.1
Paniagua, M.C.2
Lukacs, N.W.3
Kunkel, S.L.4
Karpus, W.J.5
-
35
-
-
0028803845
-
An important role for the chemokine macrophage inflammatory protein-1 in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis
-
Karpus WJ, Lukacs NW, McRae BL, Strieter RM, Kunkel SL, Miller SD. An important role for the chemokine macrophage inflammatory protein-1 in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis. J Immunol. 1995;155(10):5003-5010.
-
(1995)
J Immunol.
, vol.155
, Issue.10
, pp. 5003-5010
-
-
Karpus, W.J.1
Lukacs, N.W.2
McRae, B.L.3
Strieter, R.M.4
Kunkel, S.L.5
Miller, S.D.6
-
36
-
-
58149149835
-
CXCL12 (SDF-1) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells
-
Meiron M, Zohar Y, Anunu R, Wildbaum G, Karin N. CXCL12 (SDF-1) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells. J Exp Med. 2008;205(11):2643-2655.
-
(2008)
J Exp Med.
, vol.205
, Issue.11
, pp. 2643-2655
-
-
Meiron, M.1
Zohar, Y.2
Anunu, R.3
Wildbaum, G.4
Karin, N.5
-
37
-
-
0032519405
-
The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
-
Qin S, et al. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. J Clin Invest. 1998; 101(4):746-754.
-
(1998)
J Clin Invest.
, vol.101
, Issue.4
, pp. 746-754
-
-
Qin, S.1
-
38
-
-
0032536869
-
Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
-
Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med. 1998;187(6):875-883.
-
(1998)
J Exp Med.
, vol.187
, Issue.6
, pp. 875-883
-
-
Sallusto, F.1
Lenig, D.2
Mackay, C.R.3
Lanzavecchia, A.4
-
39
-
-
34247895422
-
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
-
Nakae S, Iwakura Y, Suto H, Galli SJ. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81(5):1258-1268.
-
(2007)
J Leukoc Biol.
, vol.81
, Issue.5
, pp. 1258-1268
-
-
Nakae, S.1
Iwakura, Y.2
Suto, H.3
Galli, S.J.4
-
40
-
-
3142774174
-
Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function
-
Colvin RA, Campanella GS, Sun J, Luster AD. Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function. J Biol Chem. 2004;279(29):30219-30227.
-
(2004)
J Biol Chem.
, vol.279
, Issue.29
, pp. 30219-30227
-
-
Colvin, R.A.1
Campanella, G.S.2
Sun, J.3
Luster, A.D.4
-
41
-
-
33746505443
-
CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis
-
Colvin RA, Campanella GS, Manice LA, Luster AD. CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis. Mol Cell Biol. 2006;26(15):5838-5849.
-
(2006)
Mol Cell Biol.
, vol.26
, Issue.15
, pp. 5838-5849
-
-
Colvin, R.A.1
Campanella, G.S.2
Manice, L.A.3
Luster, A.D.4
-
42
-
-
0036604393
-
Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis
-
Wildbaum G, Netzer N, Karin N. Plasmid DNA encoding IFN-gamma-inducible protein 10 redirects antigen-specific T cell polarization and suppresses experimental autoimmune encephalomyelitis. J Immunol. 2002;168(11):5885-5892.
-
(2002)
J Immunol.
, vol.168
, Issue.11
, pp. 5885-5892
-
-
Wildbaum, G.1
Netzer, N.2
Karin, N.3
-
43
-
-
0036721708
-
Targeting the function of IFN-/- inducible protein 10 suppresses ongoing adjuvant arthritis
-
Salomon I, Netzer N, Wildbaum G, Schif-Zuck S, Maor G, Karin N. Targeting the function of IFN-/- inducible protein 10 suppresses ongoing adjuvant arthritis. J Immunol. 2002;169(5):2685-2693.
-
(2002)
J Immunol.
, vol.169
, Issue.5
, pp. 2685-2693
-
-
Salomon, I.1
Netzer, N.2
Wildbaum, G.3
Schif-Zuck, S.4
Maor, G.5
Karin, N.6
-
44
-
-
62049085168
-
Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10
-
Sun J, Madan R, Karp CL, Braciale TJ. Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10. Nat Med. 2009;15(3):277-284.
-
(2009)
Nat Med.
, vol.15
, Issue.3
, pp. 277-284
-
-
Sun, J.1
Madan, R.2
Karp, C.L.3
Braciale, T.J.4
-
45
-
-
35548996783
-
Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7
-
Sierro F, et al. Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007;104(37):14759-14764.
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, Issue.37
, pp. 14759-14764
-
-
Sierro, F.1
-
46
-
-
33748474838
-
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
-
Burns JM, et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med. 2006; 203(9):2201-2213.
-
(2006)
J Exp Med.
, vol.203
, Issue.9
, pp. 2201-2213
-
-
Burns, J.M.1
-
47
-
-
54249115529
-
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells
-
Hartmann TN, et al. A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. J Leukoc Biol. 2008;84(4):1130-1140.
-
(2008)
J Leukoc Biol.
, vol.84
, Issue.4
, pp. 1130-1140
-
-
Hartmann, T.N.1
-
48
-
-
80055081893
-
Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
-
Drury LJ, et al. Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. Proc Natl Acad Sci U S A. 2011;108(43):17655-17660.
-
(2011)
Proc Natl Acad Sci U S A.
, vol.108
, Issue.43
, pp. 17655-17660
-
-
Drury, L.J.1
-
49
-
-
0033209897
-
The chemokine SDF-1 triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway
-
Vila-Coro AJ, Rodriguez-Frade JM, Martin De Ana A, Moreno-Ortiz MC, Martinez AC, Mellado M. The chemokine SDF-1 triggers CXCR4 receptor dimerization and activates the JAK/STAT pathway. FASEB J. 1999;13(13):1699-1710.
-
(1999)
FASEB J.
, vol.13
, Issue.13
, pp. 1699-1710
-
-
Vila-Coro, A.J.1
Rodriguez-Frade, J.M.2
Martin De Ana, A.3
Moreno-Ortiz, M.C.4
Martinez, A.C.5
Mellado, M.6
-
50
-
-
0141456120
-
CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase
-
Smit MJ, et al. CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase. Blood. 2003;102(6):1959-1965.
-
(2003)
Blood.
, vol.102
, Issue.6
, pp. 1959-1965
-
-
Smit, M.J.1
-
51
-
-
84880275285
-
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
-
Gagliani N, et al. Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells. Nat Med. 2013;19(6):739-746.
-
(2013)
Nat Med.
, vol.19
, Issue.6
, pp. 739-746
-
-
Gagliani, N.1
-
52
-
-
77955903212
-
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
-
Apetoh L, et al. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat Immunol. 2010;11(9):854-861.
-
(2010)
Nat Immunol.
, vol.11
, Issue.9
, pp. 854-861
-
-
Apetoh, L.1
-
53
-
-
0028483990
-
Treatment of murine lupus with CTLA4Ig
-
Finck BK, Linsley PS, Wofsy D. Treatment of murine lupus with CTLA4Ig. Science. 1994; 265(5176):1225-1227.
-
(1994)
Science.
, vol.265
, Issue.5176
, pp. 1225-1227
-
-
Finck, B.K.1
Linsley, P.S.2
Wofsy, D.3
-
54
-
-
0033613938
-
Arrestin-dependent formation of 2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, et al. Arrestin-dependent formation of 2 adrenergic receptor-Src protein kinase complexes. Science. 1999;283(5402):655-661.
-
(1999)
Science.
, vol.283
, Issue.5402
, pp. 655-661
-
-
Luttrell, L.M.1
-
55
-
-
0027513982
-
A mutation-induced activated state of the 2- adrenergic receptor
-
Samama P, Cotecchia S, Costa T, Lefkowitz RJ. A mutation-induced activated state of the 2- adrenergic receptor. Extending the ternary complex model. J Biol Chem. 1993;268(7):4625-4636.
-
(1993)
Extending the Ternary Complex Model. J Biol Chem.
, vol.268
, Issue.7
, pp. 4625-4636
-
-
Samama, P.1
Cotecchia, S.2
Costa, T.3
Lefkowitz, R.J.4
-
56
-
-
68949117973
-
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2
-
Izhak L, et al. A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2. J Immunol. 2009; 183(1):732-739.
-
(2009)
J Immunol.
, vol.183
, Issue.1
, pp. 732-739
-
-
Izhak, L.1
-
57
-
-
77956923012
-
A fusion protein encoding the second extracellular domain of CCR5 arrests chemokine-induced cosignaling and effectively suppresses ongoing experimental autoimmune encephalomyelitis
-
Sapir Y, Vitenshtein A, Barsheshet Y, Zohar Y, Wildbaum G, Karin N. A fusion protein encoding the second extracellular domain of CCR5 arrests chemokine-induced cosignaling and effectively suppresses ongoing experimental autoimmune encephalomyelitis. J Immunol. 2010;185(4):2589-2599.
-
(2010)
J Immunol.
, vol.185
, Issue.4
, pp. 2589-2599
-
-
Sapir, Y.1
Vitenshtein, A.2
Barsheshet, Y.3
Zohar, Y.4
Wildbaum, G.5
Karin, N.6
-
58
-
-
33645902493
-
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2
-
Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol. 2006;7(3):311-317.
-
(2006)
Nat Immunol.
, vol.7
, Issue.3
, pp. 311-317
-
-
Serbina, N.V.1
Pamer, E.G.2
-
59
-
-
33646029748
-
Severe disease, unaltered leukocyte migration, and reduced IFN- production in CXCR3-/- mice with experimental autoimmune encephalomyelitis
-
Liu L, et al. Severe disease, unaltered leukocyte migration, and reduced IFN- production in CXCR3-/- mice with experimental autoimmune encephalomyelitis. J Immunol. 2006;176(7):4399-4409.
-
(2006)
J Immunol.
, vol.176
, Issue.7
, pp. 4399-4409
-
-
Liu, L.1
-
60
-
-
0036913215
-
Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis
-
Frigerio S, et al. Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis. Nat Med. 2002;8(12):1414-1420.
-
(2002)
Nat Med.
, vol.8
, Issue.12
, pp. 1414-1420
-
-
Frigerio, S.1
-
61
-
-
1342265727
-
Probabilistic regulation of IL-4 production in Th2 cells: Accessibility at the Il4 locus
-
Guo L, Hu-Li J, Paul WE. Probabilistic regulation of IL-4 production in Th2 cells: accessibility at the Il4 locus. Immunity. 2004;20(2):193-203.
-
(2004)
Immunity.
, vol.20
, Issue.2
, pp. 193-203
-
-
Guo, L.1
Hu-Li, J.2
Paul, W.E.3
-
62
-
-
84875604499
-
Conformational biosensors reveal GPCR signalling from endosomes
-
Irannejad R, et al. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 2013; 495(7442):534-538.
-
(2013)
Nature
, vol.495
, Issue.7442
, pp. 534-538
-
-
Irannejad, R.1
-
63
-
-
84875607396
-
Cell biology: Receptor signals come in waves
-
Lohse MJ, Calebiro D. Cell biology: receptor signals come in waves. Nature. 2013;495(7442):457-458.
-
(2013)
Nature
, vol.495
, Issue.7442
, pp. 457-458
-
-
Lohse, M.J.1
Calebiro, D.2
-
64
-
-
79954608612
-
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation
-
Chaudhry A, et al. Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity. 2011; 34(4):566-578.
-
(2011)
Immunity.
, vol.34
, Issue.4
, pp. 566-578
-
-
Chaudhry, A.1
-
65
-
-
70149098555
-
Nonredundant roles for B cellderived IL-10 in immune counter-regulation
-
Madan R, et al. Nonredundant roles for B cellderived IL-10 in immune counter-regulation. J Immunol. 2009;183(4):2312-2320.
-
(2009)
J Immunol.
, vol.183
, Issue.4
, pp. 2312-2320
-
-
Madan, R.1
-
66
-
-
0029000750
-
Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis
-
McRae BL, Vanderlugt CL, Dal Canto MC, Miller SD. Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis. J Exp Med. 1995;182(1):75-85.
-
(1995)
J Exp Med.
, vol.182
, Issue.1
, pp. 75-85
-
-
McRae, B.L.1
Vanderlugt, C.L.2
Dal Canto, M.C.3
Miller, S.D.4
-
67
-
-
0346244001
-
Intracellular phospho-protein staining techniques for flow cytometry: Monitoring single cell signaling events
-
Krutzik PO, Nolan GP. Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry A. 2003;55(2):61-70.
-
(2003)
Cytometry A.
, vol.55
, Issue.2
, pp. 61-70
-
-
Krutzik, P.O.1
Nolan, G.P.2
-
68
-
-
0024660517
-
Point mutation analysis in a mammalian gene: Rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method
-
Carothers AM, Urlaub G, Mucha J, Grunberger D, Chasin LA. Point mutation analysis in a mammalian gene: rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method. Biotechniques. 1989;7(5):494-496.
-
(1989)
Biotechniques.
, vol.7
, Issue.5
, pp. 494-496
-
-
Carothers, A.M.1
Urlaub, G.2
Mucha, J.3
Grunberger, D.4
Chasin, L.A.5
-
69
-
-
15444380345
-
Targeted overexpression of IL-18 binding protein at the central nervous system overrides flexibility in functional polarization of antigenspecific Th2 cells
-
Schif-Zuck S, et al. Targeted overexpression of IL-18 binding protein at the central nervous system overrides flexibility in functional polarization of antigenspecific Th2 cells. J Immunol. 2005;174(7):4307-4315.
-
(2005)
J Immunol.
, vol.174
, Issue.7
, pp. 4307-4315
-
-
Schif-Zuck, S.1
|