Leukocyte recruitment during onset of experimental allergic encephalomyelitis is CCR1 dependent

European Journal of Immunology

Volumn 30, Issue 8, 2000, Pages 2372-2377

  Richards, David F ^a   Fernandez, Maria ^a   Caulfield, Jason ^a   Hawrylowicz, Catherine M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Chemokine; Experimental allergic encephalomyelitis; Multiple sclerosis; Receptor

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; CHEMOKINE; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CYTOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELIN PROTEIN; RANTES; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; FEMALE; GENE DELETION; HYPERSENSITIVITY; IMMUNIZATION; IMMUNOREACTIVITY; INCIDENCE; LEUKOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RNA ANALYSIS;

ANIMALS; CELL MOVEMENT; CHEMOKINE CCL2; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; IMMUNIZATION; LEUKOCYTES; MACROPHAGE INFLAMMATORY PROTEIN-1; MICE; RANTES; RECEPTORS, CHEMOKINE; RNA, MESSENGER; SKIN;

EID: 0033849381     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(2000)30:8<2372::AID-IMMU2372>3.0.CO;2-D     Document Type: Article

References (19)

1. Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors
2. Molecular cloning of leukotactin-1: A novel human beta-chemokine, a chemoattractant for neutrophils, monocytes, and lymphocytes, and a potent agonist at CC chemokine receptors 1 and 3
3. Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1
4. Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury
5. Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection
6. CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions
7. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein
8. Chemokine regulation of experimental autoimmune encephalomyelitis: Temporal and spatial expression patterns govern disease pathogenesis
9. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
10. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes
11. Chemokine expression in routine EAE
12. An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease experimental autoimmune encephalomyelitis
13. Chemokines in immune-mediated inflammation of the CNS
14. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions
15. Murine astrocytes express a functional chemokine receptor
16. IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells
17. Astrocytes express elements of the class II endocytic pathway and process central nervous system autoantigen for presentation to encephalitogenic T cells
18. CC chemokine receptors, CCR-1 and CCR-3, are potentially involved in antigen-presenting cell function of human peripheral blood monocyte-derived dendritic cells
19. Myelin oligodendrocyte glycoprotein: A novel candidate autoantigen in multiple sclerosis