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Volumn 92, Issue 5, 2014, Pages 405-417

Sequoyitol ameliorates diabetic nephropathy in diabetic rats induced with a high-fat diet and a low dose of streptozotocin

Author keywords

Diabetic nephropathy; Oxidative stress; Sequoyitol

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT; CREATININE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MALONALDEHYDE; PROTEIN P22; PROTEIN P47; REACTIVE OXYGEN METABOLITE; SEQUOYITOL; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 5-O-METHYL-MYO-INOSITOL; INOSITOL;

EID: 84899735881     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2013-0307     Document Type: Article
Times cited : (11)

References (35)
  • 1
    • 0037586497 scopus 로고    scopus 로고
    • Total antioxidant capacity
    • doi: 10.1016/S0065-2423(03)37010-6. PMID:12619709
    • Bartosz, G. 2003. Total antioxidant capacity. Adv. Clin. Chem. 37: 219-292. doi: 10.1016/S0065-2423(03)37010-6. PMID:12619709.
    • (2003) Adv. Clin. Chem , vol.37 , pp. 219-292
    • Bartosz, G.1
  • 2
    • 0028367699 scopus 로고
    • Transforming growth factor-beta and the pathogenesis of glomerular diseases
    • doi:10.1097/ 00041552-199401000-00007. PMID:7850412
    • Border, W.A. 1994. Transforming growth factor-beta and the pathogenesis of glomerular diseases. Curr. Opin. Nephrol. Hypertens. 3(1): 54-58. doi:10.1097/ 00041552-199401000-00007. PMID:7850412.
    • (1994) Curr. Opin. Nephrol. Hypertens , vol.3 , Issue.1 , pp. 54-58
    • Border, W.A.1
  • 3
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • doi:10.1038/414813a. PMID:11742414
    • Brownlee, M. 2001. Biochemistry and molecular cell biology of diabetic complications. Nature, 414(6865): 813-820. doi:10.1038/414813a. PMID:11742414.
    • (2001) Nature , vol.414 , Issue.6865 , pp. 813-820
    • Brownlee, M.1
  • 4
    • 84878985670 scopus 로고    scopus 로고
    • Effects of sequoyitol on expression of NADPH oxidase subunits p22 phox and p47 phox in rats with type 2 diabetic liver disease
    • PMID:23833934
    • Chen, X.P., Yang, J.R., Li, X.W., Hao, W., Liu, Y., and Zhang, J.X. 2013. Effects of sequoyitol on expression of NADPH oxidase subunits p22 phox and p47 phox in rats with type 2 diabetic liver disease. Yao Xue Xue Bao, 48(4): 489-494. [In Chinese]. PMID:23833934.
    • (2013) Yao Xue Xue Bao , vol.48
    • Chen, X.P.1    Yang, J.R.2    Li, X.W.3    Hao, W.4    Liu, Y.5    Zhang, J.X.6
  • 5
    • 57349167241 scopus 로고    scopus 로고
    • Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-Ay mice
    • doi:10.1142/ S0192415X08006363. PMID:19051359
    • Chen, Z.H., Li, J., Liu, J., Zhao, Y., Zhang, P., Zhang, M.X., et al. 2008. Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-Ay mice. Am. J. Chin. Med. 36(5): 939-951. doi:10.1142/ S0192415X08006363. PMID:19051359.
    • (2008) Am. J. Chin. Med , vol.36 , Issue.5 , pp. 939-951
    • Chen, Z.H.1    Li, J.2    Liu, J.3    Zhao, Y.4    Zhang, P.5    Zhang, M.X.6
  • 6
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
    • doi:10.1016/S0140-6736(02)08905-5. PMID:12086760
    • Chiasson, J.L., Josse, R.G., Gomis, R., Hanefeld, M., Karasik, A., Laakso, M., et al. 2002. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet, 359: 2072-2077. doi:10.1016/S0140-6736(02)08905-5. PMID:12086760.
    • (2002) Lancet , vol.359 , pp. 2072-2077
    • Chiasson, J.L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 7
    • 0030784837 scopus 로고    scopus 로고
    • Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes
    • PMID:9294832
    • Craven, P.A., DeRubertis, F.R., Kagan, V.E., Melhem, M., and Studer, R.K. 1997. Effects of supplementation with vitamin C or E on albuminuria, glomerular TGF-beta, and glomerular size in diabetes. J. Am. Soc. Nephrol. 8(9): 1405- 1414. PMID:9294832.
    • (1997) J. Am. Soc. Nephrol , vol.8 , Issue.9 , pp. 1405-1414
    • Craven, P.A.1    Derubertis, F.R.2    Kagan, V.E.3    Melhem, M.4    Studer, R.K.5
  • 8
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • PMID:11773609
    • Droge, W. 2002. Free radicals in the physiological control of cell function. Physiol. Rev. 82(1): 47-95. PMID:11773609.
    • (2002) Physiol. Rev , vol.82 , Issue.1 , pp. 47-95
    • Droge, W.1
  • 9
    • 84875442186 scopus 로고    scopus 로고
    • The protective effects of _-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress
    • doi:10.3390/ijms14046746. PMID:23531536
    • Feng, B., Yan, X.F., Xue, J.L., Xu, L., and Wang, H. 2013. The protective effects of _-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress. Int. J. Mol. Sci. 14(4): 6746-6756. doi:10.3390/ijms14046746. PMID:23531536.
    • (2013) Int. J. Mol. Sci , vol.14 , Issue.4 , pp. 6746-6756
    • Feng, B.1    Yan, X.F.2    Xue, J.L.3    Xu, L.4    Wang, H.5
  • 10
    • 48249085391 scopus 로고    scopus 로고
    • Oxidative stress as a major culprit in kidney disease in diabetes
    • doi:10.2337/ db08-0057. PMID:18511445
    • Forbes, J.M., Coughlan, M.T., and Cooper, M.E. 2008. Oxidative stress as a major culprit in kidney disease in diabetes. Diabetes, 57(6): 1446-1454. doi:10.2337/ db08-0057. PMID:18511445.
    • (2008) Diabetes , vol.57 , Issue.6 , pp. 1446-1454
    • Forbes, J.M.1    Coughlan, M.T.2    Cooper, M.E.3
  • 11
    • 10644262971 scopus 로고    scopus 로고
    • The Nox family of NAD(P)H oxidases: Host defense and beyond
    • doi:10.1074/jbc.R400024200. PMID:15364933
    • Geiszt, M., and Leto, T.L. 2004. The Nox family of NAD(P)H oxidases: host defense and beyond. J. Biol. Chem. 279(50): 51715-51718. doi:10.1074/jbc.R400024200. PMID:15364933.
    • (2004) J. Biol. Chem , vol.279 , Issue.50 , pp. 51715-51718
    • Geiszt, M.1    Leto, T.L.2
  • 12
    • 0033851574 scopus 로고    scopus 로고
    • Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose
    • doi:10.1046/j.1523-1755.2000.07704.x. PMID:10997686
    • Ha, H., and Lee, H.B. 2000. Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose. Kidney Int. 58(Suppl. 77): S19-S25. doi:10.1046/j.1523-1755.2000.07704.x. PMID:10997686.
    • (2000) Kidney Int , vol.58 , Issue.SUPPL. 77
    • Ha, H.1    Lee, H.B.2
  • 13
    • 77952003251 scopus 로고    scopus 로고
    • Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients
    • doi:10.1055/s-0030-1248298. PMID:20213586
    • Huyen, V.T., Phan, D.V., Thang, P., Hoa, N.K., and Ostenson, C.G. 2010. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm. Metab. Res. 42(5): 353-357. doi:10.1055/s-0030-1248298. PMID:20213586.
    • (2010) Horm. Metab. Res , vol.42 , Issue.5 , pp. 353-357
    • Huyen, V.T.1    Phan, D.V.2    Thang, P.3    Hoa, N.K.4    Ostenson, C.G.5
  • 14
    • 0035171881 scopus 로고    scopus 로고
    • Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells
    • doi:10.1046/j.1523-1755.2001.00469.x. PMID:11135061
    • Iglesias-de La Cruz, M.C., Ruiz-Torres, P., Alcami, J., Diez-Marques, L., Ortega-Velazquez, R., Chen, S., et al. 2001. Hydrogen peroxide increases extracellular matrix mRNA through TGF-beta in human mesangial cells. Kidney. Int. 59(1): 87-95. doi:10.1046/j.1523-1755.2001.00469.x. PMID:11135061.
    • (2001) Kidney. Int , vol.59 , Issue.1 , pp. 87-95
    • Ruiz-Torres, P.1    Alcami, J.2    Diez-Marques, L.3    Ortega-Velazquez, R.4    Chen, S.5
  • 15
    • 0025697262 scopus 로고
    • Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipidperoxidation and peroxidative tissue injury
    • doi:10.1016/0891-5849(90)90131-2. PMID:2079232
    • Janero, D.R. 1990. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipidperoxidation and peroxidative tissue injury. Free Radic. Biol. Med. 9(6): 515-40. doi:10.1016/0891-5849(90)90131-2. PMID:2079232.
    • (1990) Free Radic. Biol. Med , vol.9 , Issue.6 , pp. 515-540
    • Janero, D.R.1
  • 16
    • 0141755311 scopus 로고    scopus 로고
    • Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy
    • doi:10.2337/diabetes.52.10.2603. PMID:14514646
    • Kitada, M., Koya, D., Sugimoto, T., Isono, M., Araki, S., Kashiwagi, A., et al. 2003. Translocation of glomerular p47phox and p67phox by protein kinase C-beta activation is required for oxidative stress in diabetic nephropathy. Diabetes, 52(10): 2603-2614. doi:10.2337/diabetes.52.10.2603. PMID:14514646.
    • (2003) Diabetes , vol.52 , Issue.10 , pp. 2603-2614
    • Kitada, M.1    Koya, D.2    Sugimoto, T.3    Isono, M.4    Araki, S.5    Kashiwagi, A.6
  • 17
    • 0042867408 scopus 로고    scopus 로고
    • Reactive oxygen speciesregulated signaling pathways in diabetic nephropathy
    • doi:10.1097/01.ASN.0000077410.66390.0F. PMID: 12874439
    • Lee, H.B., Yu, M.R., Yang, Y., Jiang, Z., and Ha, H. 2003. Reactive oxygen speciesregulated signaling pathways in diabetic nephropathy. J. Am. Soc. Nephrol. 14(8 Suppl. 3): S241-S245. doi:10.1097/01.ASN.0000077410.66390.0F. PMID: 12874439.
    • (2003) J. Am. Soc. Nephrol , vol.14 , Issue.8 SUPPL. 3
    • Lee, H.B.1    Yu, M.R.2    Yang, Y.3    Jiang, Z.4    Ha, H.5
  • 18
    • 29644441714 scopus 로고    scopus 로고
    • NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription
    • PMID:16365456
    • Lee, K.Y., Ito, K., Hayashi, R., Mreich, E., Twigg, S., Gilbert, R.E., et al. 2006. NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. J. Immunol. 176(1): 603-615. PMID:16365456.
    • (2006) J. Immunol , vol.176 , Issue.1 , pp. 603-615
    • Lee, K.Y.1    Ito, K.2    Hayashi, R.3    Mreich, E.4    Twigg, S.5    Gilbert, R.E.6
  • 19
    • 77954342329 scopus 로고    scopus 로고
    • Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy
    • doi:10.1093/ndt/gfq063. PMID:20157172
    • Lee, S.H., Nam, B.Y., Kang, E.W., Han, S.H., Li, J.J., Kim, do., et al. 2010. Effects of an oral adsorbent on oxidative stress and fibronectin expression in experimental diabetic nephropathy. Nephrol. Dial. Transplant. 25(7): 2134-2141. doi:10.1093/ndt/gfq063. PMID:20157172.
    • (2010) Nephrol. Dial. Transplant , vol.25 , Issue.7 , pp. 2134-2141
    • Lee, S.H.1    Nam, B.Y.2    Kang, E.W.3    Han, S.H.4    Li, J.J.5    Kim, D.6
  • 20
    • 0042343830 scopus 로고    scopus 로고
    • Chemical constituents from Amentotaxus yunnanensis and Torreya yunnanensis
    • doi:10.1021/np030117b. PMID:12880325
    • Li, S.H., Zhang, H.J., Niu, X.M., Yao, P., Sun, H.D., and Fong, H.H. 2003. Chemical constituents from Amentotaxus yunnanensis and Torreya yunnanensis. J. Nat. Prod. 66(7):1002-1005. doi:10.1021/np030117b. PMID:12880325.
    • (2003) J. Nat. Prod , vol.66 , Issue.7 , pp. 1002-1005
    • Li, S.H.1    Zhang, H.J.2    Niu, X.M.3    Yao, P.4    Sun, H.D.5    Fong, H.H.6
  • 21
    • 0035174786 scopus 로고    scopus 로고
    • Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus
    • PMID:11134258
    • Melhem, M.F., Craven, P.A., and Derubertis, F.R. 2001. Effects of dietary supplementation of alpha-lipoic acid on early glomerular injury in diabetes mellitus. J. Am. Soc. Nephrol. 12(1):124-133. PMID:11134258.
    • (2001) J. Am. Soc. Nephrol , vol.12 , Issue.1 , pp. 124-133
    • Melhem, M.F.1    Craven, P.A.2    Derubertis, F.R.3
  • 22
    • 33750938708 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 differentially mediates fibronectin and inflammatory cytokine expression in kidney tubular cells
    • doi:10.1152/ajprenal.00013.2006. PMID:16720864
    • Qi, W., Chen, X., Holian, J., Mreich, E., Twigg, S., Gilbert, R.E., et al. 2006. Transforming growth factor-beta1 differentially mediates fibronectin and inflammatory cytokine expression in kidney tubular cells. Am. J. Physiol. Renal. Physiol. 291(5): F1070-F1077. doi:10.1152/ajprenal.00013.2006. PMID:16720864.
    • (2006) Am. J. Physiol. Renal. Physiol , vol.291 , Issue.5
    • Qi, W.1    Chen, X.2    Holian, J.3    Mreich, E.4    Twigg, S.5    Gilbert, R.E.6
  • 23
    • 33750030516 scopus 로고    scopus 로고
    • Oxidative stress in young Zucker rats with impaired glucose tolerance is diminished by acarbose
    • doi:10.1055/s-2006-950397. PMID:16981139
    • Rosen, P., and Osmers, A. 2006. Oxidative stress in young Zucker rats with impaired glucose tolerance is diminished by acarbose. Horm. Metab. Res. 38(9): 575-586. doi:10.1055/s-2006-950397. PMID:16981139.
    • (2006) Horm. Metab. Res , vol.38 , Issue.9 , pp. 575-586
    • Rosen, P.1    Osmers, A.2
  • 24
    • 33847011714 scopus 로고    scopus 로고
    • Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: Amelioration by soluble TGF-beta type II receptor
    • doi:10.2337/db06-1018. PMID:17259382
    • Russo, L.M., del Re, E., Brown, D., and Lin, H.Y. 2007. Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes, 56(2): 380-388. doi:10.2337/db06-1018. PMID:17259382.
    • (2007) Diabetes , vol.56 , Issue.2 , pp. 380-388
    • Russo, L.M.1    del Re, E.2    Brown, D.3    Lin, H.Y.4
  • 25
    • 21044436751 scopus 로고    scopus 로고
    • NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy
    • doi:10.1152/ ajprenal.00221.2004. PMID:15687247
    • Satoh, M., Fujimoto, S., Haruna, Y., Arakawa, S., Horike, H., Komai, N., et al. 2005. NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy. Am. J. Physiol. Renal Physiol. 288(6): F1144-F1152. doi:10.1152/ ajprenal.00221.2004. PMID:15687247.
    • (2005) Am. J. Physiol. Renal Physiol , vol.288 , Issue.6
    • Satoh, M.1    Fujimoto, S.2    Haruna, Y.3    Arakawa, S.4    Horike, H.5    Komai, N.6
  • 26
    • 78649913769 scopus 로고    scopus 로고
    • Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: Implications in type2 diabetic nephropathy
    • doi:10.1152/ajprenal.00028. 2010. PMID:20630933
    • Sedeek, M., Callera, G., Montezano, A., Gutsol, A., Heitz, F., Szyndralewiez, C., et al. 2010. Critical role of Nox4-based NADPH oxidase in glucose-induced oxidative stress in the kidney: implications in type2 diabetic nephropathy. Am. J. Physiol. Renal Physiol. 299(6): F1348-F1358. doi:10.1152/ajprenal.00028. 2010. PMID:20630933.
    • (2010) Am. J. Physiol. Renal Physiol , vol.299 , Issue.6
    • Sedeek, M.1    Callera, G.2    Montezano, A.3    Gutsol, A.4    Heitz, F.5    Szyndralewiez, C.6
  • 27
    • 6344248758 scopus 로고    scopus 로고
    • Differential effects of TGF-beta1 and BMP-4 on the hypoxic induction of cyclooxygenase-2 in human pulmonary artery smooth muscle cells
    • doi:10.1152/ajplung.00012.2004. PMID:15220111
    • Sheares, K.K., Jeffery, T.K., Long, L., Yang, X., and Morrell, N.W. 2004. Differential effects of TGF-beta1 and BMP-4 on the hypoxic induction of cyclooxygenase-2 in human pulmonary artery smooth muscle cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 287(5): L919-L927. doi:10.1152/ajplung.00012.2004. PMID:15220111.
    • (2004) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.287 , Issue.5
    • Sheares, K.K.1    Jeffery, T.K.2    Long, L.3    Yang, X.4    Morrell, N.W.5
  • 28
    • 84859470850 scopus 로고    scopus 로고
    • Herbal constituent sequoyitol improves hyperglycemia and glucose intolerance by targeting hepatocytes, adipocytes, and _-cells
    • doi:10.1152/ajpendo.00479.2011. PMID:22297305
    • Shen, H., Shao, M., Cho, K.W., Wang, S., Chen, Z., Sheng, L., et al. 2012. Herbal constituent sequoyitol improves hyperglycemia and glucose intolerance by targeting hepatocytes, adipocytes, and _-cells. Am. J. Physiol. Endocrinol. Metab. 302(8): E932-E940. doi:10.1152/ajpendo.00479.2011. PMID:22297305.
    • (2012) Am. J. Physiol. Endocrinol. Metab , vol.302 , Issue.8
    • Shen, H.1    Shao, M.2    Cho, K.W.3    Wang, S.4    Chen, Z.5    Sheng, L.6
  • 29
    • 77953553534 scopus 로고    scopus 로고
    • Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats
    • doi:10. 3109/10715761003733901. PMID:20370563
    • Sivakumar, S., Palsamy, P., and Subramanian, S.P. 2010. Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats. Free Radic. Res. 44(6): 668-678. doi:10. 3109/10715761003733901. PMID:20370563.
    • (2010) Free Radic. Res , vol.44 , Issue.6 , pp. 668-678
    • Sivakumar, S.1    Palsamy, P.2    Subramanian, S.P.3
  • 30
    • 84876497088 scopus 로고    scopus 로고
    • Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy
    • doi:10.1016/j.bbrc.2013.02. 120. PMID:23541575
    • Sun, Y.M., Su, Y., Li, J., and Wang, L.F. 2013. Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy. Biochem. Biophys. Res. Commun. 433(4): 359-361. doi:10.1016/j.bbrc.2013.02. 120. PMID:23541575.
    • (2013) Biochem. Biophys. Res. Commun , vol.433 , Issue.4 , pp. 359-361
    • Sun, Y.M.1    Su, Y.2    Li, J.3    Wang, L.F.4
  • 31
    • 0034533082 scopus 로고    scopus 로고
    • Reactive oxygen species in cell signaling
    • PMID:11076791
    • Thannickal, V.J., and Fanburg, B.L. 2000. Reactive oxygen species in cell signaling. Am. J. Physiol. 279(6): L1005-L1028. PMID:11076791.
    • (2000) Am. J. Physiol , vol.279 , Issue.6
    • Thannickal, V.J.1    Fanburg, B.L.2
  • 32
    • 36048950801 scopus 로고    scopus 로고
    • Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria
    • doi:10.1152/ajprenal.00274.2007. PMID: 17804483
    • Wang, A., Ziyadeh, F.N., Lee, E.Y., Pyagay, P.E., Sung, S.H., Sheardown, S.A., et al. 2007. Interference with TGF-beta signaling by Smad3-knockout in mice limits diabetic glomerulosclerosis without affecting albuminuria. Am. J. Physiol. Renal Physiol. 293(5): F1657-F1665. doi:10.1152/ajprenal.00274.2007. PMID: 17804483.
    • (2007) Am. J. Physiol. Renal Physiol , vol.293 , Issue.5
    • Wang, A.1    Ziyadeh, F.N.2    Lee, E.Y.3    Pyagay, P.E.4    Sung, S.H.5    Sheardown, S.A.6
  • 33
    • 47349127081 scopus 로고    scopus 로고
    • Studies on chemical constituents from whole plants of Crossostephium chinense
    • PMID:18619349
    • Yang, X.W., Zou, L., Wu, Q., and Fu, D.X. 2008. Studies on chemical constituents from whole plants of Crossostephium chinense. Zhongguo Zhong Yao Za Zhi, 33(8): 905-908. PMID:18619349.
    • (2008) Zhongguo Zhong Yao Za Zhi , vol.33 , Issue.8 , pp. 905-908
    • Yang, X.W.1    Zou, L.2    Wu, Q.3    Fu, D.X.4
  • 34
    • 84879330119 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 deficiency aggravates glucose intolerance via impairment of islet microvascular density in mice with high-fat diet
    • doi: 10.1155/2013/405284. PMID:23671869
    • Yuan, L., Wang, Y., Lu, C., and Li, X. 2013. Angiotensin-converting enzyme 2 deficiency aggravates glucose intolerance via impairment of islet microvascular density in mice with high-fat diet. J. Diabetes. Res. 2013: 405284. doi: 10.1155/2013/405284. PMID:23671869.
    • (2013) J. Diabetes. Res , vol.2013 , pp. 405284
    • Yuan, L.1    Wang, Y.2    Lu, C.3    Li, X.4
  • 35
    • 65549131015 scopus 로고    scopus 로고
    • The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model
    • doi:10.1155/2008/704045. PMID: 19132099
    • Zhang, M., Lv, X.Y., Li, J., Xu, Z.G., and Chen, L. 2008. The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Exp. Diabetes. Res. 2008: 704045. doi:10.1155/2008/704045. PMID: 19132099.
    • (2008) Exp. Diabetes. Res , vol.2008 , pp. 704045
    • Zhang, M.1    Lv, X.Y.2    Li, J.3    Xu, Z.G.4    Chen, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.