메뉴 건너뛰기




Volumn 288, Issue 6 57-6, 2005, Pages

NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular superoxide in rats with experimental diabetic nephropathy

Author keywords

In situ detection of nitric oxide and reactive oxygen species; Low temperature SDS PAGE; Tetrahydrobiopterin

Indexed keywords

ARGININE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIPHENYLIODONIUM SALT; NITRIC OXIDE SYNTHASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; STREPTOZOCIN; TETRAHYDROBIOPTERIN;

EID: 21044436751     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00221.2004     Document Type: Article
Times cited : (323)

References (45)
  • 1
    • 85047690420 scopus 로고    scopus 로고
    • Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression
    • Alp NJ, Mussa S, Khoo J, Cai S, Guzik T, Jefferson A, Goh N, Rockett KA, and Channon KM. Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression. J Clin Invest 112: 725-735, 2003.
    • (2003) J Clin Invest , vol.112 , pp. 725-735
    • Alp, N.J.1    Mussa, S.2    Khoo, J.3    Cai, S.4    Guzik, T.5    Jefferson, A.6    Goh, N.7    Rockett, K.A.8    Channon, K.M.9
  • 2
    • 0025006809 scopus 로고
    • Receptor-mediated generation of an EDRF-like intermediate in a neuronal cell line detected by spin trapping techniques
    • Arroyo CM, Forray C, el-Fakahany EE, and Rosen GM. Receptor-mediated generation of an EDRF-like intermediate in a neuronal cell line detected by spin trapping techniques. Biochem Biophys Res Commun 170: 1177-1183, 1990.
    • (1990) Biochem Biophys Res Commun , vol.170 , pp. 1177-1183
    • Arroyo, C.M.1    Forray, C.2    El-Fakahany, E.E.3    Rosen, G.M.4
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412, 1991.
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
    • Baynes JW and Thorpe SR. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 48: 1-9, 1999.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 5
    • 0037428209 scopus 로고    scopus 로고
    • Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity
    • D'uscio LV, Milstien S, Richardson D, Smith L, and Katusic ZS. Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity. Circ Res 92: 88-95, 2003.
    • (2003) Circ Res , vol.92 , pp. 88-95
    • D'uscio, L.V.1    Milstien, S.2    Richardson, D.3    Smith, L.4    Katusic, Z.S.5
  • 6
    • 0042864155 scopus 로고    scopus 로고
    • Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibility by interventive insulin treatment
    • Etoh T, Inoguchi T, Kakimoto M, Sonoda N, Kobayashi K, Kuroda J, Sumimoto H, and Nawata H. Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibility by interventive insulin treatment. Diabetologia 46: 1428-1437, 2003.
    • (2003) Diabetologia , vol.46 , pp. 1428-1437
    • Etoh, T.1    Inoguchi, T.2    Kakimoto, M.3    Sonoda, N.4    Kobayashi, K.5    Kuroda, J.6    Sumimoto, H.7    Nawata, H.8
  • 7
    • 0030048496 scopus 로고    scopus 로고
    • Oxidative stress and diabetic vascular complications
    • Giugliano D, Ceriello A, and Paolisso G. Oxidative stress and diabetic vascular complications. Diabetes Care 19: 257-267, 1996.
    • (1996) Diabetes Care , vol.19 , pp. 257-267
    • Giugliano, D.1    Ceriello, A.2    Paolisso, G.3
  • 8
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • Guzik TJ, Mussa S, Gastaldi D, Sadowski J, Ratnatunga C, Pillai R, and Channon KM. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 105: 1656-1662, 2002.
    • (2002) Circulation , vol.105 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 9
    • 0028348166 scopus 로고
    • DNA damage in the kidneys of diabetic rats exhibiting microalbuminuria
    • Ha H, Kim C, Son Y, Chung MH, and Kim KH. DNA damage in the kidneys of diabetic rats exhibiting microalbuminuria. Free Radic Biol Med 16: 271-274, 1994.
    • (1994) Free Radic Biol Med , vol.16 , pp. 271-274
    • Ha, H.1    Kim, C.2    Son, Y.3    Chung, M.H.4    Kim, K.H.5
  • 10
    • 0036841861 scopus 로고    scopus 로고
    • NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels
    • Hamilton CA, Brosnan MJ, Al-Benna S, Berg G, and Dominiczak AF. NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels. Hypertension 40: 755-762, 2002.
    • (2002) Hypertension , vol.40 , pp. 755-762
    • Hamilton, C.A.1    Brosnan, M.J.2    Al-Benna, S.3    Berg, G.4    Dominiczak, A.F.5
  • 11
    • 0345532411 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells
    • Hattori Y, Nakanishi N, Akimoto K, Yoshida M, and Kasai K. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells. Arterioscler Thromb Vasc Biol 23: 176-182, 2003.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 176-182
    • Hattori, Y.1    Nakanishi, N.2    Akimoto, K.3    Yoshida, M.4    Kasai, K.5
  • 12
    • 0034602878 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: Evidence for a dysfunctional nitric oxide synthase
    • Heitzer T, Brockhoff C, Mayer B, Warnholtz A, Mollnau H, Henne S, Meinertz T, and Munzel T. Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers: evidence for a dysfunctional nitric oxide synthase. Circ Res 86: E36-41, 2000.
    • (2000) Circ Res , vol.86
    • Heitzer, T.1    Brockhoff, C.2    Mayer, B.3    Warnholtz, A.4    Mollnau, H.5    Henne, S.6    Meinertz, T.7    Munzel, T.8
  • 14
    • 0031453830 scopus 로고    scopus 로고
    • Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy
    • Horie K, Miyata T, Maeda K, Miyata S, Sugiyama S, Sakai H, van Ypersole de Strihou C, Monnier VM, Witztum JL, and Kurokawa K. Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy. J Clin Invest 100: 2995-3004, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 2995-3004
    • Horie, K.1    Miyata, T.2    Maeda, K.3    Miyata, S.4    Sugiyama, S.5    Sakai, H.6    Van Ypersole De Strihou, C.7    Monnier, V.M.8    Witztum, J.L.9    Kurokawa, K.10
  • 15
    • 0032547768 scopus 로고    scopus 로고
    • Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
    • Hotta M, Tashiro F, Ikegami H, Niwa H, Ogihara T, Yodoi J, and Miyazaki J. Pancreatic beta cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes. J Exp Med 188: 1445-1451, 1998.
    • (1998) J Exp Med , vol.188 , pp. 1445-1451
    • Hotta, M.1    Tashiro, F.2    Ikegami, H.3    Niwa, H.4    Ogihara, T.5    Yodoi, J.6    Miyazaki, J.7
  • 18
    • 0042867404 scopus 로고    scopus 로고
    • Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats
    • Koya D, Hayashi K, Kitada M, Kashiwagi A, Kikkawa R, and Haneda M. Effects of antioxidants in diabetes-induced oxidative stress in the glomeruli of diabetic rats. J Am Soc Nephrol 14: S250-S253, 2003.
    • (2003) J Am Soc Nephrol , vol.14
    • Koya, D.1    Hayashi, K.2    Kitada, M.3    Kashiwagi, A.4    Kikkawa, R.5    Haneda, M.6
  • 19
    • 0038604446 scopus 로고    scopus 로고
    • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: Implications for uncoupling endothelial nitric-oxide synthase
    • Kuzkaya N, Weissmann N, Harrison DG, and Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J Biol Chem 278: 22546-22554, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 22546-22554
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.G.3    Dikalov, S.4
  • 21
    • 0036088542 scopus 로고    scopus 로고
    • Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney
    • Li N, Yi FX, Spurrier JL, Bobrowitz CA, and Zou AP. Production of superoxide through NADH oxidase in thick ascending limb of Henle's loop in rat kidney. Am J Physiol Renal Physiol 282: F1111-F1119, 2002.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Li, N.1    Yi, F.X.2    Spurrier, J.L.3    Bobrowitz, C.A.4    Zou, A.P.5
  • 23
    • 0023023315 scopus 로고
    • Increased superoxide anion release from human endothelial cells in response to cytokines
    • Matsubara T and Ziff M. Increased superoxide anion release from human endothelial cells in response to cytokines. J Immunol 137: 3295-3298, 1986.
    • (1986) J Immunol , vol.137 , pp. 3295-3298
    • Matsubara, T.1    Ziff, M.2
  • 24
    • 0035174786 scopus 로고    scopus 로고
    • Effects of dietary supplementation of α-lipoic acid on early glomerular injury in diabetes mellitus
    • Melhem MF, Craven PA, and Derubertis FR. Effects of dietary supplementation of α-lipoic acid on early glomerular injury in diabetes mellitus. J Am Soc Nephrol 12: 124-133, 2001.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 124-133
    • Melhem, M.F.1    Craven, P.A.2    Derubertis, F.R.3
  • 25
    • 1642504352 scopus 로고    scopus 로고
    • A detective story for biomédical footprints towards new therapeutic interventions in diabetic nephropathy
    • Miyata T and Kurokawa K. A detective story for biomédical footprints towards new therapeutic interventions in diabetic nephropathy. Intern Med 42: 1165-1171, 2003.
    • (2003) Intern Med , vol.42 , pp. 1165-1171
    • Miyata, T.1    Kurokawa, K.2
  • 26
    • 0023770113 scopus 로고
    • Free radicals and diabetes
    • Oberley LW. Free radicals and diabetes. Free Radic Biol Med 5: 113-124, 1988.
    • (1988) Free Radic Biol Med , vol.5 , pp. 113-124
    • Oberley, L.W.1
  • 27
    • 0034711470 scopus 로고    scopus 로고
    • Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction
    • Oelze M, Mollnau H, Hoffmann N, Warnholtz A, Bodenschatz M, Smolenski A, Walter U, Skatchkov M, Meinertz T, and Munzel T. Vasodilator-stimulated phosphoprotein serine 239 phosphorylation as a sensitive monitor of defective nitric oxide/cGMP signaling and endothelial dysfunction. Circ Res 87: 999-1005, 2000.
    • (2000) Circ Res , vol.87 , pp. 999-1005
    • Oelze, M.1    Mollnau, H.2    Hoffmann, N.3    Warnholtz, A.4    Bodenschatz, M.5    Smolenski, A.6    Walter, U.7    Skatchkov, M.8    Meinertz, T.9    Munzel, T.10
  • 28
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, and Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 91: 2546-2551, 1993.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 29
    • 0036145348 scopus 로고    scopus 로고
    • Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: Effects of ACEI and ARB
    • Onozato ML, Tojo A, Goto A, Fujita T, and Wilcox CS. Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB. Kidney Int 61: 186-194, 2002.
    • (2002) Kidney Int , vol.61 , pp. 186-194
    • Onozato, M.L.1    Tojo, A.2    Goto, A.3    Fujita, T.4    Wilcox, C.S.5
  • 30
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RM, Ashton DS, and Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333: 664-666, 1988.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.1    Ashton, D.S.2    Moncada, S.3
  • 31
    • 0026470180 scopus 로고
    • Generation of superoxide by purified brain nitric oxide synthase
    • Pou S, Pou WS, Bredt DS, Snyder SH, and Rosen GM. Generation of superoxide by purified brain nitric oxide synthase. J Biol Chem 267: 24173-24176, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 24173-24176
    • Pou, S.1    Pou, W.S.2    Bredt, D.S.3    Snyder, S.H.4    Rosen, G.M.5
  • 32
    • 0034803984 scopus 로고    scopus 로고
    • Tetrahydrobiopterin reverses the inhibition of nitric oxide by high glucose in cultured murine mesangial cells
    • Prabhakar SS. Tetrahydrobiopterin reverses the inhibition of nitric oxide by high glucose in cultured murine mesangial cells. Am J Physiol Renal Physiol 281: F179-F188, 2001.
    • (2001) Am J Physiol Renal Physiol , vol.281
    • Prabhakar, S.S.1
  • 34
    • 0035050847 scopus 로고    scopus 로고
    • The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes
    • Schnackenberg CG and Wilcox CS. The SOD mimetic tempol restores vasodilation in afferent arterioles of experimental diabetes. Kidney Int 59: 1859-1864, 2001.
    • (2001) Kidney Int , vol.59 , pp. 1859-1864
    • Schnackenberg, C.G.1    Wilcox, C.S.2
  • 37
    • 0027305213 scopus 로고
    • Analysis of 6R- and 6S-tetrahydrobiopterin and other pterins by reversed-phase ion-pair liquid-chromatography with fluorimetric detection by post-column sodium nitrite oxidation
    • Tani Y and Ohno T. Analysis of 6R- and 6S-tetrahydrobiopterin and other pterins by reversed-phase ion-pair liquid-chromatography with fluorimetric detection by post-column sodium nitrite oxidation. J Chromatogr 617: 249-255, 1993.
    • (1993) J Chromatogr , vol.617 , pp. 249-255
    • Tani, Y.1    Ohno, T.2
  • 38
    • 0035800889 scopus 로고    scopus 로고
    • Methods of detection of vascular reactive species: Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite
    • Tarpey MM and Fridovich I. Methods of detection of vascular reactive species: nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res 89: 224-236, 2001.
    • (2001) Circ Res , vol.89 , pp. 224-236
    • Tarpey, M.M.1    Fridovich, I.2
  • 42
    • 0031030864 scopus 로고    scopus 로고
    • Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms
    • Venema RC, Ju H, Zou R, Ryan JW, and Venema VJ. Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms. J Biol Chem 272: 1276-1282, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 1276-1282
    • Venema, R.C.1    Ju, H.2    Zou, R.3    Ryan, J.W.4    Venema, V.J.5
  • 44
    • 0032475865 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • 2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem 273: 25804-25808, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 45
    • 0035097458 scopus 로고    scopus 로고
    • Production and actions of superoxide in the renal medulla
    • Zou AP, Li N, and Cowley AW Jr. Production and actions of superoxide in the renal medulla. Hypertension 37: 547-553, 2001.
    • (2001) Hypertension , vol.37 , pp. 547-553
    • Zou, A.P.1    Li, N.2    Cowley Jr., A.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.