Angiotensin-converting enzyme 2 deficiency aggravates glucose intolerance via impairment of islet microvascular density in mice with high-fat diet

Journal of Diabetes Research

Volumn 2013, Issue , 2013, Pages

  Yuan, Li ^a   Wang, Ying ^a   Lu, Chunli ^a   Li, Xiaoya ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; GLUCOSE; INSULIN; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CAPILLARY DENSITY; DISEASE EXACERBATION; ENDOCRINE FUNCTION; ENZYME DEFICIENCY; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; LIPID DIET; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; WILD TYPE;

EID: 84879330119     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2013/405284     Document Type: Article

References (37)

1. Skipworth J. R. A., Szabadkai G., Olde Damink S. W. M., Leung P. S., Humphries S. E., Montgomery H. E., Review article: pancreatic renin-angiotensin systems in health and disease. Alimentary Pharmacology & Therapeutics 2011 34 8 840 852
2. Tipnis S. R., Hooper N. M., Hyde R., Karran E., Christie G., Turner A. J., A human homolog of angiotensin-converting enzyme: cloning and functional expression as a captopril-insensitive carboxypeptidase. Journal of Biological Chemistry 2000 275 43 33238 33243 2-s2.0-0034721906 10.1074/jbc.M002615200
3. Donoghue M., Hsieh F., Baronas E., Godbout K., Gosselin M., Stagliano N., Donovan M., Woolf B., Robison K., Jeyaseelan R., Breitbart R. E., Acton S., A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circulation Research 2000 87 5 e1 e9 2-s2.0-0038053724
4. Rice G. I., Thomas D. A., Grant P. J., Turner A. J., Hooper N. M., Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism. Biochemical Journal 2004 383 1 45 51 2-s2.0-6344246036 10.1042/BJ20040634 (Pubitemid 39389449)
5. Ferrario C. M., ACE2: more of Ang-(1-7) or less Ang II? Current Opinion in Nephrology and Hypertension 2011 20 1 1 6
6. Santos R. A. S., Ferreira A. J., Simões E Silva A. C., Recent advances in the angiotensin-converting enzyme 2-angiotensin(1-7)-Mas axis. Experimental Physiology 2008 93 5 519 527 2-s2.0-42649115768 10.1113/expphysiol.2008.042002 (Pubitemid 351595060)
7. Cheng Q., Leung P. S., An update on the islet renin-angiotensin system. Peptides 2011 32 5 1087 1095 2-s2.0-79955467663 10.1016/j.peptides.2011.03.003
8. Leung P. S., The physiology of a local renin-angiotensin system in the pancreas. Journal of Physiology 2007 580 1 31 37 2-s2.0-33947526470 10.1113/jphysiol.2006.126193 (Pubitemid 46470642)
9. Batlle D., Soler M. J., Ye M., ACE2 and diabetes: ACE of ACEs? Diabetes 2010 59 12 2994 2996 2-s2.0-78650046602 10.2337/db10-1205
10. Chappell M. C., Millsted A., Diz D. I., Brosnihan K. B., Ferrario C. M., Evidence for an intrinsic angiotensin system in the canine pancreas. Journal of Hypertension 1991 9 8 751 759 2-s2.0-0025881221
11. Lau T., Carlsson P. O., Leung P. S., Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets. Diabetologia 2004 47 2 240 248 2-s2.0-1542374750 10.1007/s00125-003- 1295-1 (Pubitemid 38315360)
12. Lam K. Y., Leung P. S., Regulation and expression of a renin-angiotensin system in human pancreas and pancreatic endocrine tumours. European Journal of Endocrinology 2002 146 4 567 572 2-s2.0-0036224357 (Pubitemid 34436471)
13. Tikellis C., Cooper M. E., Thomas M. C., Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes. International Journal of Biochemistry and Cell Biology 2006 38 5-6 737 751 2-s2.0-33644843826 10.1016/j.biocel.2005.08.007 (Pubitemid 43363410)
14. Bindom S. M., Lazartigues E., The sweeter side of ACE2: physiological evidence for a role in diabetes. Molecular and Cellular Endocrinology 2009 302 2 193 202 2-s2.0-62949127898 10.1016/j.mce.2008.09.020
15. Leung P. S., Carlsson P. O., Pancreatic islet renin angiotensin system: its novel roles in islet function and in diabetes mellitus. Pancreas 2005 30 4 293 298 2-s2.0-17844367376 10.1097/01.mpa.0000158028.76666.76 (Pubitemid 40586804)
16. Leung P. S., Mechanisms of protective effects induced by blockade of the renin-angiotensin system: novel role of the pancreatic islet angiotensin-generating system in Type 2 diabetes. Diabetic Medicine 2007 24 2 110 116 2-s2.0-33846576694 10.1111/j.1464-5491.2007.02072.x (Pubitemid 46174932)
17. Tikellis C., Wookey P. J., Candido R., Andrikopoulos S., Thomas M. C., Cooper M. E., Improved islet morphology after blockade of the renin-angiotensin system in the ZDF rat. Diabetes 2004 53 4 989 997 2-s2.0-1842475446 10.2337/diabetes.53.4.989 (Pubitemid 38436611)
18. Yuan L., Li X., Li J., Li H. l., Cheng S. S., Effects of renin-angiotensin system blockade on the islet morphology and function in rats with long-term high-fat diet. Acta Diabetologica. In press
19. Scheen A. J., Renin-angiotensin system inhibition prevents type 2 diabetes mellitus-part 1: a meta-analysis of randomised clinical trials. Diabetes and Metabolism 2004 30 6 487 496 2-s2.0-11244294737 (Pubitemid 40070350)
20. Gillespie E. L., White C. M., Kardas M., Lindberg M., Coleman C. I., The impact of ACE inhibitors or angiotensin II type 1 receptor blockers on the development of new-onset type 2 diabetes. Diabetes Care 2005 28 9 2261 2266 2-s2.0-24144490705 10.2337/diacare.28.9.2261 (Pubitemid 41242483)
21. Vejakama P., Thakkinstian A., Lertrattananon D., Ingsathit A., Ngarmukos C., Attia J., Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysis. Diabetologia 2011 55 3 566 578
22. Wong D. W., Oudit G. Y., Reich H., Kassiri Z., Zhou J., Liu Q. C., Backx P. H., Penninger J. M., Herzenberg A. M., Scholey J. W., Loss of Angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury. American Journal of Pathology 2007 171 2 438 451 2-s2.0-34548295365 10.2353/ajpath.2007.060977 (Pubitemid 47344677)
23. Akirav E. M., Baquero M. T., Opare-Addo L. W., Akirav M., Galvan E., Kushner J. A., Rimm D. L., Herold K. C., Glucose and inflammation control islet vascular density and β -cell function in NOD mice control of islet vasculature and vascular endothelial growth factor by glucose. Diabetes 2011 60 3 876 883 2-s2.0-79952378639 10.2337/db10-0793
24. Iwai M., Horiuchi M., Devil and angel in the renin-angiotensin system: ACE-angiotensin II-AT1 receptor axis vs. ACE2-angiotensin-(1-7)-Mas receptor axis. Hypertension Research 2009 32 7 533 536
25. Chappell M. C., Emerging evidence for a functional angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis: more than regulation of blood pressure? Hypertension 2007 50 4 596 599 2-s2.0-34548851716 10.1161/ HYPERTENSIONAHA.106.076216 (Pubitemid 47442717)
26. Putnam K., Shoemaker R., Yiannikouris F., Cassis L., The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and hypertension of the metabolic syndrome. American Journal of Physiology 2012 15 302 H1219 H1230
27. Souza-Mello V., Gregório B. M., Cardoso-De-Lemos F. S., De Carvalho L., Aguila M. B., Mandarim-De-Lacerda C. A., Comparative effects of telmisartan, sitagliptin and metformin alone or in combination on obesity, insulin resistance, and liver and pancreas remodelling in C57BL/6 mice fed on a very high-fat diet. Clinical Science 2010 119 6 239 250 2-s2.0-77956051448 10.1042/CS20100061
28. Bindom S. M., Hans C. P., Xia H., Boulares A. H., Lazartigues E., Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice. Diabetes 2010 59 10 2540 2548 2-s2.0-77957558776 10.2337/db09-0782
29. Agudo J., Ayuso E., Jimenez V., Casellas A., Mallol C., Salavert A., Tafuro S., Obach M., Ruzo A., Moya M., Pujol A., Bosch F., Vascular endothelial growth factor-mediated islet hypervascularization and inflammation contribute to progressive reduction of β -cell mass. Diabetes 2012 61 11 2851 2861
30. Cleaver O., Dor Y., Vascular instruction of pancreas development. Development 2012 139 16 2833 2843
31. Brissova M., Shostak A., Shiota M., Wiebe P. O., Poffenberger G., Kantz J., Chen Z., Carr C., Jerome W. G., Chen J., Baldwin H. S., Nicholson W., Bader D. M., Jetton T., Gannon M., Powers A. C., Pancreatic islet production of vascular endothelial growth factor-A is essential for islet vascularization, revascularization, and function. Diabetes 2006 55 11 2974 2985 2-s2.0-33845540482 10.2337/db06-0690 (Pubitemid 44923633)
32. Jabs N., Franklin L., Brenner M. B., Gromada J., Ferrara N., Wollheim C. B., Lammert E., Reduced insulin secretion and content in VEGF-A deficient mouse pancreatic islets. Experimental and Clinical Endocrinology and Diabetes 2008 116 1 S46 S49 2-s2.0-54549108972 10.1055/s-2008-1081486
33. Brissova M., Fowler M., Wiebe P., Shostak A., Shiota M., Radhika A., Lin P. C., Gannon M., Powers A. C., Intraislet endothelial cells contribute to revascularization of transplanted pancreatic islets. Diabetes 2004 53 5 1318 1325 2-s2.0-2342650809 10.2337/diabetes.53.5.1318 (Pubitemid 38569019)
34. Vickers C., Hales P., Kaushik V., Dick L., Gavin J., Tang J., Godbout K., Parsons T., Baronas E., Hsieh F., Acton S., Patane M., Nichols A., Tummino P., Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. Journal of Biological Chemistry 2002 277 17 14838 14843 2-s2.0-18544378161 10.1074/jbc.M200581200 (Pubitemid 34952556)
35. Castan-laurell I., Dray C., Knauf C., Kunduzova O., Valet P., Apelin, a promising target for type 2 diabetes treatment? Trends in Endocrinology & Metabolism 2012 23 5 234 241
36. Winzell M. S., Magnusson C., Ahrén B., The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice. Regulatory Peptides 2005 131 1-3 12 17 2-s2.0-25844530179 10.1016/j.regpep.2005.05.004 (Pubitemid 41392985)
37. Guo L., Li Q., Wang W., Yu P., Pan H., Li P., Sun Y., Zhang J., Apelin inhibits insulin secretion in pancreatic β -cells by activation of PI3-kinase-phosphodiesterase 3B. Endocrine Research 2009 34 4 142 154 2-s2.0-72949111358 10.3109/07435800903287079