-
1
-
-
0034708832
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
-
Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 275: 9047-9054, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
2
-
-
0037059330
-
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action
-
Aguirre V, Werner ED, Giraud J, Lee YH, Shoelson SE, White MF. Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action. J Biol Chem 277: 1531-1537, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 1531-1537
-
-
Aguirre, V.1
Werner, E.D.2
Giraud, J.3
Lee, Y.H.4
Shoelson, S.E.5
White, M.F.6
-
3
-
-
0027253950
-
Chiro-inositol deficiency and insulin resistance: A comparison of the chiro-inositol- and the myo-inositol- containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects
-
Asplin I, Galasko G, Larner J. chiro-inositol deficiency and insulin resistance: a comparison of the chiro-inositol- and the myo-inositol- containing insulin mediators isolated from urine, hemodialysate, and muscle of control and type II diabetic subjects. Proc Natl Acad Sci U S A 90: 5924-5928, 1993.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5924-5928
-
-
Asplin, I.1
Galasko, G.2
Larner, J.3
-
5
-
-
23944435412
-
Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action
-
Brautigan DL, Brown M, Grindrod S, Chinigo G, Kruszewski A, Lukasik SM, Bushweller JH, Horal M, Keller S, Tamura S, Heimark DB, Price J, Larner AN, Larner J. Allosteric activation of protein phosphatase 2C by D-chiro-inositol-galactosamine, a putative mediator mimetic of insulin action. Biochemistry 44: 11067-11073, 2005.
-
(2005)
Biochemistry
, vol.44
, pp. 11067-11073
-
-
Brautigan, D.L.1
Brown, M.2
Grindrod, S.3
Chinigo, G.4
Kruszewski, A.5
Lukasik, S.M.6
Bushweller, J.H.7
Horal, M.8
Keller, S.9
Tamura, S.10
Heimark, D.B.11
Price, J.12
Larner, A.N.13
Larner, J.14
-
6
-
-
47249156463
-
Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans
-
Cefalu WT, Ye J, Wang ZQ. Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. Endocr Metab Immune Disord Drug Targets 8: 78-81, 2008.
-
(2008)
Endocr Metab Immune Disord Drug Targets
, vol.8
, pp. 78-81
-
-
Cefalu, W.T.1
Ye, J.2
Wang, Z.Q.3
-
7
-
-
51649098471
-
Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome
-
Cheang KI, Baillargeon JP, Essah PA, Ostlund RE Jr, Apridonize T, Islam L, Nestler JE. Insulin-stimulated release of D-chiro-inositol-containing inositolphosphoglycan mediator correlates with insulin sensitivity in women with polycystic ovary syndrome. Metabolism 57: 1390-1397, 2008.
-
(2008)
Metabolism
, vol.57
, pp. 1390-1397
-
-
Cheang, K.I.1
Baillargeon, J.P.2
Essah, P.A.3
Ostlund Jr., R.E.4
Apridonize, T.5
Islam, L.6
Nestler, J.E.7
-
8
-
-
57349167241
-
Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-Ay mice
-
Chen ZH, Li J, Liu J, Zhao Y, Zhang P, Zhang MX, Zhang L. Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-Ay mice. Am J Chin Med 36: 939-951, 2008.
-
(2008)
Am J Chin Med
, vol.36
, pp. 939-951
-
-
Chen, Z.H.1
Li, J.2
Liu, J.3
Zhao, Y.4
Zhang, P.5
Zhang, M.X.6
Zhang, L.7
-
9
-
-
78751499277
-
Lipocalin-13 regulates glucose metabolism by both insulin-dependent and insulin-independent mechanisms
-
Cho KW, Zhou Y, Sheng L, Rui L. Lipocalin-13 regulates glucose metabolism by both insulin-dependent and insulin-independent mechanisms. Mol Cell Biol 31: 450-457, 2011.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 450-457
-
-
Cho, K.W.1
Zhou, Y.2
Sheng, L.3
Rui, L.4
-
10
-
-
77955356609
-
D-Pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice
-
Dang NT, Mukai R, Yoshida K, Ashida H. D-Pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice. Biosci Biotechnol Biochem 74: 1062-1067, 2010.
-
(2010)
Biosci Biotechnol Biochem
, vol.74
, pp. 1062-1067
-
-
Dang, N.T.1
Mukai, R.2
Yoshida, K.3
Ashida, H.4
-
11
-
-
0029968296
-
Phosphoinositides as regulators in membrane traffic
-
De Camilli P, Emr SD, McPherson PS, Novick P. Phosphoinositides as regulators in membrane traffic. Science 271: 1533-1539, 1996.
-
(1996)
Science
, vol.271
, pp. 1533-1539
-
-
de Camilli, P.1
Emr, S.D.2
McPherson, P.S.3
Novick, P.4
-
12
-
-
0037381715
-
Tetrahydroisoquinoline alkaloids and 2-deoxyribonolactones from Aristolochia arcuata
-
Francisco MC, Nasser AL, Lopes LM. Tetrahydroisoquinoline alkaloids and 2-deoxyribonolactones from Aristolochia arcuata. Phytochemistry 62: 1265-1270, 2003.
-
(2003)
Phytochemistry
, vol.62
, pp. 1265-1270
-
-
Francisco, M.C.1
Nasser, A.L.2
Lopes, L.M.3
-
13
-
-
0019630320
-
2-dependent glycogen synthase phosphatase (phosphoprotein phosphatase IA) from rat liver
-
2-dependent glycogen synthase phosphatase (phosphoprotein phosphatase IA) from rat liver. Eur J Biochem 119: 503-510, 1981.
-
(1981)
Eur J Biochem
, vol.119
, pp. 503-510
-
-
Hiraga, A.1
Kikuchi, K.2
Tamura, S.3
Tsuiki, S.4
-
14
-
-
0034006587
-
Isolation of INS-1-derived cell lines with robust ATP- sensitive K channel-dependent and-independent glucose-stimulated insulin secretion
-
Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB. Isolation of INS-1-derived cell lines with robust ATP- sensitive K channel-dependent and-independent glucose-stimulated insulin secretion. Diabetes 49: 424-430, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 424-430
-
-
Hohmeier, H.E.1
Mulder, H.2
Chen, G.3
Henkel-Rieger, R.4
Prentki, M.5
Newgard, C.B.6
-
15
-
-
0032925340
-
Mechanisms of TNF-alpha-induced insulin resistance
-
Hotamisligil GS. Mechanisms of TNF-alpha-induced insulin resistance. Exp Clin Endocrinol Diabetes 107: 119-125, 1999.
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, pp. 119-125
-
-
Hotamisligil, G.S.1
-
16
-
-
0028362194
-
Tumor necrosis factor alpha inhibits signaling from the insulin receptor
-
Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM. Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 91: 4854-4858, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 4854-4858
-
-
Hotamisligil, G.S.1
Murray, D.L.2
Choy, L.N.3
Spiegelman, B.M.4
-
17
-
-
77952003251
-
Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients
-
Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab Res 42: 353-357, 2010.
-
(2010)
Horm Metab Res
, vol.42
, pp. 353-357
-
-
Huyen, V.T.1
Phan, D.V.2
Thang, P.3
Hoa, N.K.4
Ostenson, C.G.5
-
19
-
-
33745841934
-
Pinitol from soybeans reduces postprandial blood glucose in patients with type 2 diabetes mellitus
-
Kang MJ, Kim JI, Yoon SY, Kim JC, Cha IJ. Pinitol from soybeans reduces postprandial blood glucose in patients with type 2 diabetes mellitus. J Med Food 9: 182-186, 2006.
-
(2006)
J Med Food
, vol.9
, pp. 182-186
-
-
Kang, M.J.1
Kim, J.I.2
Yoon, S.Y.3
Kim, J.C.4
Cha, I.J.5
-
20
-
-
0141736851
-
Urinary chiro-inositol and myoinositol excretion is elevated in the diabetic db/db mouse and streptozotocin diabetic rat
-
Kawa JM, Przybylski R, Taylor CG. Urinary chiro-inositol and myoinositol excretion is elevated in the diabetic db/db mouse and streptozotocin diabetic rat. Exp Biol Med (Maywood) 228: 907-914, 2003.
-
(2003)
Exp Biol Med (Maywood)
, vol.228
, pp. 907-914
-
-
Kawa, J.M.1
Przybylski, R.2
Taylor, C.G.3
-
21
-
-
0033372658
-
Inositol phosphoglycans in diabetes and obesity: Urinary levels of IPG A-type and IPG P-type, and relationship to pathophysiological changes
-
Kunjara S, Wang DY, Greenbaum AL, McLean P, Kurtz A, Rademacher TW. Inositol phosphoglycans in diabetes and obesity: urinary levels of IPG A-type and IPG P-type, and relationship to pathophysiological changes. Mol Genet Metab 68: 488-502, 1999.
-
(1999)
Mol Genet Metab
, vol.68
, pp. 488-502
-
-
Kunjara, S.1
Wang, D.Y.2
Greenbaum, A.L.3
McLean, P.4
Kurtz, A.5
Rademacher, T.W.6
-
22
-
-
38949092924
-
Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients
-
Kuriyan R, Rajendran R, Bantwal G, Kurpad AV. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 31: 216-220, 2008.
-
(2008)
Diabetes Care
, vol.31
, pp. 216-220
-
-
Kuriyan, R.1
Rajendran, R.2
Bantwal, G.3
Kurpad, A.V.4
-
23
-
-
78149237932
-
D-Chiro-inositol glycans in insulin signaling and insulin resistance
-
Larner J, Brautigan DL, Thorner MO. D-Chiro-inositol glycans in insulin signaling and insulin resistance. Mol Med 16: 543-552, 2010.
-
(2010)
Mol Med
, vol.16
, pp. 543-552
-
-
Larner, J.1
Brautigan, D.L.2
Thorner, M.O.3
-
24
-
-
0042343830
-
Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis
-
Li SH, Zhang HJ, Niu XM, Yao P, Sun HD, Fong HH. Chemical constituents from Amentotaxus yunnanensis and Torreyayunnanensis. J Nat Prod 66: 1002-1005, 2003.
-
(2003)
J Nat Prod
, vol.66
, pp. 1002-1005
-
-
Li, S.H.1
Zhang, H.J.2
Niu, X.M.3
Yao, P.4
Sun, H.D.5
Fong, H.H.6
-
25
-
-
0026766846
-
Insulin mediator stimulation of pyruvate dehydrogenase phosphatases
-
Lilley K, Zhang C, Villar-Palasi C, Larner J, Huang L. Insulin mediator stimulation of pyruvate dehydrogenase phosphatases. Arch Biochem Biophys 296: 170-174, 1992.
-
(1992)
Arch Biochem Biophys
, vol.296
, pp. 170-174
-
-
Lilley, K.1
Zhang, C.2
Villar-Palasi, C.3
Larner, J.4
Huang, L.5
-
26
-
-
77953957172
-
The beta-cell in human type 2 diabetes
-
Marchetti P, Lupi R, Del Guerra S, Bugliani M, Marselli L, Boggi U. The beta-cell in human type 2 diabetes. Adv Exp Med Biol 654: 501-514, 2010.
-
(2010)
Adv Exp Med Biol
, vol.654
, pp. 501-514
-
-
Marchetti, P.1
Lupi, R.2
Guerra, S.3
Bugliani, M.4
Marselli, L.5
Boggi, U.6
-
27
-
-
57749091885
-
Reciprocal control of pyruvate dehydrogenase kinase and phosphatase by inositol phosphoglycans. Dynamic state set by "push-pull" system
-
McLean P, Kunjara S, Greenbaum AL, Gumaa K, Lopez-Prados J, Martin-Lomas M, Rademacher TW. Reciprocal control of pyruvate dehydrogenase kinase and phosphatase by inositol phosphoglycans. Dynamic state set by "push-pull" system. J Biol Chem 283: 33428-33436, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 33428-33436
-
-
McLean, P.1
Kunjara, S.2
Greenbaum, A.L.3
Gumaa, K.4
Lopez-Prados, J.5
Martin-Lomas, M.6
Rademacher, T.W.7
-
28
-
-
38549132277
-
Inositol derivatives: Evolution and functions
-
Michell RH. Inositol derivatives: evolution and functions. Nat Rev Mol Cell Biol 9: 151-161, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 151-161
-
-
Michell, R.H.1
-
29
-
-
0033648253
-
Role of inositolphosphoglycan mediators of insulin action in the polycystic ovary syndrome
-
Nestler JE, Jakubowicz DJ, Iuorno MJ. Role of inositolphosphoglycan mediators of insulin action in the polycystic ovary syndrome. J Pediatr Endocrinol Metab 13, Suppl 5: 1295-1298, 2000.
-
(2000)
J Pediatr Endocrinol Metab
, vol.13
, Issue.5 SUPPL.
, pp. 1295-1298
-
-
Nestler, J.E.1
Jakubowicz, D.J.2
Iuorno, M.J.3
-
30
-
-
0029933665
-
Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
-
Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM. Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271: 13018-13022, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 13018-13022
-
-
Peraldi, P.1
Hotamisligil, G.S.2
Buurman, W.A.3
White, M.F.4
Spiegelman, B.M.5
-
31
-
-
25144523930
-
Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice
-
Ren D, Li M, Duan C, Rui L. Identification of SH2-B as a key regulator of leptin sensitivity, energy balance, and body weight in mice. Cell Metab 2: 95-104, 2005.
-
(2005)
Cell Metab
, vol.2
, pp. 95-104
-
-
Ren, D.1
Li, M.2
Duan, C.3
Rui, L.4
-
32
-
-
33846822094
-
Neuronal SH2B1 is essential for controlling energy and glucose homeostasis
-
Ren D, Zhou Y, Morris D, Li M, Li Z, Rui L. Neuronal SH2B1 is essential for controlling energy and glucose homeostasis. J Clin Invest 117: 397-406, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 397-406
-
-
Ren, D.1
Zhou, Y.2
Morris, D.3
Li, M.4
Li, Z.5
Rui, L.6
-
33
-
-
0035144307
-
Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways
-
Rui L, Aguirre V, Kim JK, Shulman GI, Lee A, Corbould A, Dunaif A, White MF. Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways. J Clin Invest 107: 181-189, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 181-189
-
-
Rui, L.1
Aguirre, V.2
Kim, J.K.3
Shulman, G.I.4
Lee, A.5
Corbould, A.6
Dunaif, A.7
White, M.F.8
-
34
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414: 799-806, 2001.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
35
-
-
77953553534
-
Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in strep-tozotocin-induced diabetic rats
-
Sivakumar S, Palsamy P, Subramanian SP. Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in strep-tozotocin-induced diabetic rats. Free Radic Res 44: 668-678, 2010.
-
(2010)
Free Radic Res
, vol.44
, pp. 668-678
-
-
Sivakumar, S.1
Palsamy, P.2
Subramanian, S.P.3
-
36
-
-
0036065047
-
G(q/11) is involved in insulin-stimulated inositol phosphoglycan putative mediator generation in rat liver membranes: Co-localization of G(q/11) with the insulin receptor in membrane vesicles
-
Sleight S, Wilson BA, Heimark DB, Larner J. G(q/11) is involved in insulin-stimulated inositol phosphoglycan putative mediator generation in rat liver membranes: co-localization of G(q/11) with the insulin receptor in membrane vesicles. Biochem Biophys Res Commun 295: 561-569, 2002.
-
(2002)
Biochem Biophys Res Commun
, vol.295
, pp. 561-569
-
-
Sleight, S.1
Wilson, B.A.2
Heimark, D.B.3
Larner, J.4
-
37
-
-
0031757099
-
Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity
-
Uysal KT, Wiesbrock SM, Hotamisligil GS. Functional analysis of tumor necrosis factor (TNF) receptors in TNF-alpha-mediated insulin resistance in genetic obesity. Endocrinology 139: 4832-4838, 1998.
-
(1998)
Endocrinology
, vol.139
, pp. 4832-4838
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Hotamisligil, G.S.3
-
38
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389: 610-614, 1997.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
40
-
-
0030805703
-
Phos-phoinositide 3-kinases: A conserved family of signal transducers
-
Vanhaesebroeck B, Leevers SJ, Panayotou G, Waterfield MD. Phos-phoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem Sci 22: 267-272, 1997.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 267-272
-
-
Vanhaesebroeck, B.1
Leevers, S.J.2
Panayotou, G.3
Waterfield, M.D.4
-
41
-
-
33745156121
-
Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: A randomised controlled trial
-
Walker AF, Marakis G, Simpson E, Hope JL, Robinson PA, Hassanein M, Simpson HC. Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial. Br J Gen Pract 56: 437-443, 2006.
-
(2006)
Br J Gen Pract
, vol.56
, pp. 437-443
-
-
Walker, A.F.1
Marakis, G.2
Simpson, E.3
Hope, J.L.4
Robinson, P.A.5
Hassanein, M.6
Simpson, H.C.7
-
42
-
-
0036710280
-
IRS proteins and the common path to diabetes
-
White MF. IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 283: E413-E422, 2002.
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
White, M.F.1
-
43
-
-
47349127081
-
Studies on chemical constituents from whole plants of Crossostephium chinense
-
Yang XW, Zou L, Wu Q, Fu DX. [Studies on chemical constituents from whole plants of Crossostephium chinense]. Zhongguo Zhong Yao Za Zhi 33: 905-908, 2008.
-
(2008)
Zhongguo Zhong Yao Za Zhi
, vol.33
, pp. 905-908
-
-
Yang, X.W.1
Zou, L.2
Wu, Q.3
Fu, D.X.4
-
44
-
-
66449096802
-
Identification of MUP1 as a regulator for glucose and lipid metabolism in mice
-
Zhou Y, Jiang L, Rui L. Identification of MUP1 as a regulator for glucose and lipid metabolism in mice. J Biol Chem 284: 11152-11159, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 11152-11159
-
-
Zhou, Y.1
Jiang, L.2
Rui, L.3
-
45
-
-
69749112905
-
Effects of chemical constituents of Crossostephium chinense on insulin secretion in rat islets in vitro
-
Zou L, Wu Q, Yang X, Fu D. [Effects of chemical constituents of Crossostephium chinense on insulin secretion in rat islets in vitro]. Zhongguo Zhong Yao Za Zhi 34: 1401-1405, 2009.
-
(2009)
Zhongguo Zhong Yao Za Zhi
, vol.34
, pp. 1401-1405
-
-
Zou, L.1
Wu, Q.2
Yang, X.3
Fu, D.4
|