The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis

Thrombosis and Haemostasis

Volumn 111, Issue 5, 2014, Pages 970-980

  Schouten, Marcel ^a   De Boer, J Daan ^a   Kager, Liesbeth M ^a   Roelofs, Joris J T H ^a   Meijers, Joost C M ^a   Esmon, Charles T ^b   Levi, Marcel ^a   van 't Veer, Cornelis ^a   van der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Coagulation; Endothelial protein C receptor; Pneumonia; Sepsis; Streptococcus pneumoniae

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; CELL SURFACE RECEPTOR; PROCR PROTEIN, MOUSE;

ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL LOAD; BACTERIAL TRANSMISSION; BLOOD CLOTTING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOLOGY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; STREPTOCOCCUS PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; DISEASE MODEL; ENDOTHELIUM; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; KNOCKOUT MOUSE; LUNG; METABOLISM; MICROBIOLOGY; MUTANT MOUSE STRAIN; NEUTROPHIL; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; BACTERIAL LOAD; CELL MOVEMENT; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIUM; FEMALE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEUTROPHILS; PNEUMONIA, PNEUMOCOCCAL; RECEPTORS, CELL SURFACE; SEPSIS; STREPTOCOCCUS PNEUMONIAE;

EID: 84899719549     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH13-10-0859     Document Type: Article

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