Activated protein C protects against ventilator-induced pulmonary capillary leak

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 296, Issue 6, 2009, Pages

  Finigan, James H ^a   Boueiz, Adel ^b   Wilkinson, Emily ^a   Damico, Rachel ^b   Skirball, Jarrett ^b   Hyun, Hae Pae ^b   Damarla, Mahendra ^b   Hasan, Emile ^b   Pearse, David B ^b   Reddy, Sekhar P ^c   Grigoryev, Dmitry N ^b   Cheadle, Christopher ^b   Esmon, Charles T ^d   Garcia, Joe G N ^e   Hassoun, Paul M ^b,f  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f Division of Pulmonary and Critical Care Medicine   (United States)

Author keywords

Endothelial protein C receptor; Mechanical stress; Vascular barrier function; Ventilator induced lung injury

Indexed keywords

ANTICOAGULANT ACTIVATED PROTEIN C; ANTITHROMBIN; BETA6 INTEGRIN; ENDOTHELIAL PROTEIN C RECEPTOR; EVANS BLUE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PLASMA PROTEIN; RHO KINASE; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BLOOD VESSEL PERMEABILITY; CAPILLARY LEAK SYNDROME; COMPLEX FORMATION; CONTROLLED STUDY; JUGULAR VEIN; LUNG ENDOTHELIUM; LUNG INJURY; LUNG LAVAGE; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; VENTILATOR;

ACUTE LUNG INJURY; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARIES; CAPILLARY PERMEABILITY; EXTRAVASCULAR LUNG WATER; GENE EXPRESSION; GLYCOPROTEINS; MALE; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN C; PULMONARY CIRCULATION; PULMONARY EDEMA; RESPIRATION, ARTIFICIAL; RHO-ASSOCIATED KINASES; STRESS, MECHANICAL;

EID: 67049099316     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.90555.2008     Document Type: Article

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