The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis

Thrombosis and Haemostasis

Volumn 109, Issue 4, 2013, Pages 726-737

  Kager, Liesbeth M ^a   Roelofs, Joris J T H ^a   de Vos, Alex F ^a   Wieland, Catharina W ^a   Schouten, Marcel ^a   Meijers, Joost C M ^a   Isermann, Berend ^b   van't Veer, Cornelis ^a   Esmon, Charles T ^c   van der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Activated protein C; Endothelial protein C receptor; Infection; Inflammation; Lung; Mice; Tuberculosis

Indexed keywords

ACTIVATED PROTEIN C; CYTOKINE; ENDOTHELIAL PROTEIN C RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCLONAL ANTIBODY;

ADULT; AGED; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; BLOOD CLOTTING; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE OVEREXPRESSION; HISTOPATHOLOGY; HOST RESISTANCE; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOLOGY; INFLAMMATION; LUNG GRANULOMA; LUNG INFILTRATE; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUBERCULOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, CD; BLOOD COAGULATION; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GLYCOPROTEINS; HUMANS; INFLAMMATION MEDIATORS; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PROMOTER REGIONS, GENETIC; PROTEIN C; RECEPTOR, TIE-2; RECEPTORS, CELL SURFACE; TIME FACTORS; TUBERCULOSIS, PULMONARY; UP-REGULATION;

EID: 84875920093     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH12-11-0859     Document Type: Article

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