Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia

Journal of Immunology

Volumn 168, Issue 7, 2002, Pages 3507-3511

  Rijneveld, Anita W ^a   Levi, Marcel ^a   Florquin, Sandrine ^a   Speelman, Peter ^a   Carmeliet, Peter ^a   Van der Poll, Tom ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; CHEMOKINE; CYTOKINE; GROWTH FACTOR; INTERLEUKIN 6; UROKINASE; UROKINASE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; COLONY FORMING UNIT; CONTROLLED STUDY; GRANULOCYTE; HOST RESISTANCE; LOBAR PNEUMONIA; LUNG ALVEOLUS; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS PNEUMONIAE;

EID: 0036533484     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.7.3507     Document Type: Article

References (41)

1. Tumour biology: Membrane proteases in focus
2. Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes
3. Distinct patterns of urokinase receptor (uPAR) expression by leukemic cells and peripheral blood cells
4. Urokinase receptor: An activation antigen in human T lymphocytes
5. Cancer invasion and tissue remodeling: Cooperation of protease systems and cell types
6. Upregulation of monocyte urokinase plasminogen activator receptor during human endotoxemia
7. Concurrent upregulation of urokinase plasminogen activator receptor and CD11b during tuberculosis and experimental endotoxemia
8. Borrelia burgdorferi and other bacterial products induce expression and release of the urokinase receptor (CD87)
9. Structure and function of the urokinase receptor
10. The urokinase receptor: A cell surface, regulated chemokine
11. The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes
12. The urokinase receptor is required for human monocyte chemotaxis in vitro
13. uPA, uPAR, PAI-1: Key intersection of proteolytic, adhesive and chemotactic highways?
14. Mβ2-CD11b/CD18) during neutrophil polarization
15. Physical association of complement receptor type 3 and urokinase-type plasminogen activator receptor in neutrophil membranes
16. Urokinase receptor: A molecular organizer in cellular communication
17. The urokinase-type-plasminogen-activator receptor (CD87) is a pleiotropic molecule
18. CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits
19. 2 integrin CD18 in the local accumulation of neutrophils in pulmonary and cutaneous inflammation in the rabbit
20. Neutrophil migration mechanisms, with an emphasis on the pulmonary vasculature
21. Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection
22. Practice guidelines for the management of community-acquired pneumonia in adults: Infectious Diseases Society of America
23. Severe community-acquired pneumonia: Epidemiology and prognostic factors
24. Physiological consequences of loss of plasminogen activator gene function in mice
25. Generation and characterization of urokinase receptor-deficient mice
26. Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia
27. Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: A gene targeting and gene transfer study in mice
28. Cytokines and pulmonary host defenses
29. The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice
30. CD18 adhesion blockade decreases bacterial clearance and neutrophil recruitment after intrapulmonary E. coli, but not after S. aureus
31. P-selectin/ICAM-1 double mutant mice: Acute emigration of neutrophils into the peritoneum is completely absent but is normal into pulmonary alveoli
32. Innate immunity and pulmonary host defense
33. Nonproteolytic role for the urokinase receptor in cellular migration in vivo
34. Proteases and cancer invasion: From belief to certainty: AACR meeting on proteases and protease inhibitors in cancer Nyborg, Denmark, 14-18 June 1998
35. 2 integrins in vivo
36. Urokinase: A chemotactic factor for polymorphonuclear leukocytes in vivo
37. Human urokinase-type plasminogen activator stimulates chemotaxis of human neutrophils
38. Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect
39. Function of the urokinase receptor (CD87) in neutrophil chemotaxis
40. Urokinase-type plasminogen activator in inflammatory cell recruitment and host defense against Pneumocystis carinii in mice
41. Urokinase is required for the pulmonary inflammatory response to Cryptococcus neoformans: A murine transgenic model