Dietary flavanols modulate the transcription of genes associated with cardiovascular pathology without changes in their DNA methylation state

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Milenkovic, Dragan ^a,b   Vanden Berghe, Wim ^c,d   Boby, Céline ^e   Leroux, Christine ^e   Declerck, Ken ^d   Szic, Katarzyna Szarc Vel ^d   Heyninck, Karen ^c   Laukens, Kris ^d   Bizet, Martin ^f   Defrance, Matthieu ^f   Dedeurwaerder, Sarah ^f   Calonne, Emilie ^f   Fuks, Francois ^f   Haegeman, Guy ^c   Haenen, Guido R M M ^g   Bast, Aalt ^g   Weseler, Antje R ^g  

^a CRNH AUVERGNE   (France)

^b UNIVERSITÉ CLERMONT AUVERGNE   (France)

^c GHENT UNIVERSITY   (Belgium)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e UMR1213 HERBIVORES   (France)

^f UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^g MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; FLAVANOL DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MONOMERIC AND OLIGOMERIC FLAVANOL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; FLAVONOID; GRAPE SEED EXTRACT; TRANSCRIPTOME;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CELL ADHESION; CELL INFILTRATION; CHEMOTAXIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOSKELETON; DIET SUPPLEMENTATION; DIETARY INTAKE; DNA METHYLATION; ENDOTHELIUM CELL; EPIGENETICS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GRAPE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOCOMPETENT CELL; MALE; MONOCYTE; NORMAL HUMAN; NUTRIGENOMICS; PLANT SEED; SMOKING; TREATMENT DURATION; CARDIOVASCULAR DISEASES; CELL CULTURE; COCULTURE; CPG ISLAND; DNA MICROARRAY; DNA SEQUENCE; DRUG EFFECTS; GENETICS; LEUKOCYTE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; UMBILICAL VEIN ENDOTHELIAL CELL;

ADULT; CARDIOVASCULAR DISEASES; CELL ADHESION; CELLS, CULTURED; COCULTURE TECHNIQUES; CPG ISLANDS; DNA METHYLATION; FLAVONOIDS; GENE EXPRESSION REGULATION; GRAPE SEED EXTRACT; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION, GENETIC; TRANSCRIPTOME;

EID: 84899708552     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0095527     Document Type: Article

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