CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrier

Science Translational Medicine

Volumn 4, Issue 119, 2012, Pages

  Man, Shumei ^a   Tucky, Barbara ^a   Cotleur, Anne ^a   Drazba, Judith ^a   Takeshita, Yukio ^a   Ransohoff, Richard M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD19 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; NEUTRALIZING ANTIBODY; STROMAL CELL DERIVED FACTOR 1; AUTACOID; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; VIRUS T ANTIGEN;

ADULT; ARTICLE; B LYMPHOCYTE; BLOOD BRAIN BARRIER; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE MIGRATION; LYMPHOCYTE MIGRATION; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEAR STRESS; T LYMPHOCYTE; VOLUNTEER; BLOOD FLOW; CELL CULTURE; COCULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; INFLAMMATION; LYMPHOCYTE; MECHANICAL STRESS; METABOLISM; MIDDLE AGED; PERFUSION; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; TIME; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

ADULT; ANTIBODIES, NEUTRALIZING; ANTIGENS, CD14; ANTIGENS, CD19; ANTIGENS, POLYOMAVIRUS TRANSFORMING; B-LYMPHOCYTES; BLOOD-BRAIN BARRIER; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHEMOKINE CXCL12; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; LYMPHOCYTES; MIDDLE AGED; MONOCYTES; PERFUSION; RECEPTORS, CXCR4; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; STRESS, MECHANICAL; TIME FACTORS; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; TRANSFECTION; YOUNG ADULT;

EID: 84856587379     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3003197     Document Type: Article

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