Morin ameliorates chemically induced liver fibrosis in vivo and inhibits stellate cell proliferation in vitro by suppressing Wnt/β-catenin signaling

Toxicology and Applied Pharmacology

Volumn 277, Issue 2, 2014, Pages 210-220

  MadanKumar, Perumal ^a   NaveenKumar, Perumal ^a   Manikandan, Samidurai ^a   Devaraj, Halagowder ^a   NiranjaliDevaraj, Sivasithamparam ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Diethylnitrosamine; G1 cell cycle arrest; Liver fibrosis; LX 2 cells; Morin; Catenin

Indexed keywords

BETA CATENIN; CYCLIN D1; DIETHYLNITROSAMINE; GLYCOGEN SYNTHASE KINASE 3; MORIN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFICACY; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; LIPID LIVER LEVEL; LIVER FIBROSIS; LIVER FUNCTION; LIVER PROTECTION; LIVER WEIGHT; MALE; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STELLATE CELL; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

DIETHYLNITROSAMINE; G1 CELL CYCLE ARREST; LIVER FIBROSIS; LX-2 CELLS; MORIN; Β-CATENIN;

ANIMALS; BETA CATENIN; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; CYTOPROTECTION; DIETHYLNITROSAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; G1 PHASE CELL CYCLE CHECKPOINTS; GLYCOGEN SYNTHASE KINASE 3; HEPATIC STELLATE CELLS; HUMANS; LIPID PEROXIDATION; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; OXIDATIVE STRESS; RATS; RATS, WISTAR; TIME FACTORS; WNT SIGNALING PATHWAY;

EID: 84899688415     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.03.008     Document Type: Article

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