Cudratricusxanthone A protect pancreatic beta cells from cytokines-mediated toxicity through the inhibition of NF-κB and STAT pathways

International Immunopharmacology

Volumn 21, Issue 1, 2014, Pages 26-33

  Lee, Dong Sung ^a   Jeong, Gil Saeng ^b  

^a Wonkwang University   (South Korea)

^b Keimyung University   (South Korea)

Author keywords

Cudratricusxanthone A; Cytokines; Cytoprotection; Glucose stimulated insulin secretion; NF B; Pancreatic cell

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CUDRATRICUSXANTHONE A; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; JANUS KINASE; LIVER PROTECTIVE AGENT; NITRIC OXIDE; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; UNCLASSIFIED DRUG; INSULIN; XANTHONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CELL DAMAGE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; DRUG CYTOTOXICITY; GENE EXPRESSION; HEPG2 CELL LINE; INSULIN RELEASE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RINM5F CELL LINE; UPREGULATION; ANIMAL; CELL DEATH; CELL LINE; CELL SURVIVAL; DOWN REGULATION; DRUG EFFECTS; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MORACEAE; PATHOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; TRANSCRIPTION INITIATION;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; DOWN-REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MALE; MORACEAE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; XANTHONES;

EID: 84899678225     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.04.008     Document Type: Article

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