Gene deletion of protein tyrosine phosphatase 1B protects against sepsis-induced cardiovascular dysfunction and mortality

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 5, 2014, Pages 1032-1044

  Coquerel, David ^a,b   Neviere, Remi ^c   Delile, Eugenie ^a,b   Mulder, Paul ^a,b   Marechal, Xavier ^c   Montaigne, David ^c   Renet, Sylvanie ^a,b   Remy Jouet, Isabelle ^a,b   Gomez, Elodie ^a,b   Henry, Jean Paul ^a,b   Do Rego, Jean Claude ^b,e   Richard, Vincent ^a,b   Tamion, Fabienne ^a,b,d,f  

^a INSERM   (France)

^b UNIVERSITY OF ROUEN   (France)

^c UNIV LILLE   (France)

^d ROUEN UNIVERSITY HOSPITAL   (France)

^e Platform of Behavioural Analysis (SCAC) Faculty of Medicine   (France)

^f HÔPITAL CHARLES NICOLLE   (France)

Author keywords

inflammation; nitric oxide synthase type III

Indexed keywords

AS 279; CYCLOOXYGENASE 2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCOPROTEIN GP 91; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR INFLAMMATION; CARDIOVASCULAR MORTALITY; CARDITIS; CELL INFILTRATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENDOTHELIAL DYSFUNCTION; ENZYME PHOSPHORYLATION; EXPERIMENTAL HEART FAILURE; FLUID RESUSCITATION; GENE DELETION; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE PRESSURE; HEART PROTECTION; HEART VENTRICLE ENDDIASTOLIC PRESSURE; IN VITRO STUDY; LOCOMOTION; MESENTERIC ARTERY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SEPSIS; SEPTIC SHOCK; SEPTIC SHOCK INDUCED CARDIOVASCULAR DYSFUNCTION; SURVIVAL; SURVIVAL RATE; VASCULITIS; VASOCONSTRICTION; VASODILATATION; WILD TYPE;

INFLAMMATION; NITRIC OXIDE SYNTHASE TYPE III;

ANIMALS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CECUM; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HEART RATE; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; LIGATION; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MESENTERIC ARTERIES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PUNCTURES; RNA, MESSENGER; SEPSIS; SIGNAL TRANSDUCTION; TIME FACTORS; VASCULAR CELL ADHESION MOLECULE-1; VASODILATION; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 84899655256     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303450     Document Type: Article

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