메뉴 건너뛰기




Volumn 283, Issue 5 52-5, 2002, Pages

Role of ceramide in TNF-α-induced impairment of endothelium-dependent vasorelaxation in coronary arteries

Author keywords

Free radicals; Lipids; Nitric oxide; Tumor necrosis factor

Indexed keywords

BRADYKININ; CALCIMYCIN; CERAMIDE; CYTOKINE; DESIPRAMINE; FREE RADICAL; LIPID; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; SPHINGOMYELIN PHOSPHODIESTERASE; SUPEROXIDE; TIRON; TUMOR NECROSIS FACTOR ALPHA;

EID: 0036838876     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00318.2002     Document Type: Article
Times cited : (64)

References (69)
  • 1
    • 0022647311 scopus 로고
    • Modifications of sphingomyelin and phosphatidylcholine metabolism by tricyclic antidepressants and phenothiazines
    • Albouz S, Le Saux F, Wenger D, Hauw JJ, and Baumann N. Modifications of sphingomyelin and phosphatidylcholine metabolism by tricyclic antidepressants and phenothiazines. Life Sci 38: 357-363, 1986.
    • (1986) Life Sci , vol.38 , pp. 357-363
    • Albouz, S.1    Le Saux, F.2    Wenger, D.3    Hauw, J.J.4    Baumann, N.5
  • 2
    • 0024393126 scopus 로고
    • Anti-EDRF effect of tumor necrosis factor in isolated, perfused cat carotid arteries
    • Aoki N, Siegfried M, and Lefer AM. Anti-EDRF effect of tumor necrosis factor in isolated, perfused cat carotid arteries. Am J Physiol Heart Circ Physiol 256: H1509-H1512, 1989.
    • (1989) Am J Physiol Heart Circ Physiol , vol.256
    • Aoki, N.1    Siegfried, M.2    Lefer, A.M.3
  • 3
    • 0027478716 scopus 로고
    • Serum tumor necrosis factor levels in acute myocardial infarction and unstable angina pectoris
    • Basaran Y, Basaran MM, Babacan KF, Ener B, Okay T, Gok H, and Ozdemir M. Serum tumor necrosis factor levels in acute myocardial infarction and unstable angina pectoris. Angiology 44: 332-337, 1993.
    • (1993) Angiology , vol.44 , pp. 332-337
    • Basaran, Y.1    Basaran, M.M.2    Babacan, K.F.3    Ener, B.4    Okay, T.5    Gok, H.6    Ozdemir, M.7
  • 5
    • 0030671491 scopus 로고    scopus 로고
    • Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo
    • Bhagat K and Vallance P. Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation 96: 3042-3047, 1997.
    • (1997) Circulation , vol.96 , pp. 3042-3047
    • Bhagat, K.1    Vallance, P.2
  • 6
    • 0032545259 scopus 로고    scopus 로고
    • Lactosylceramide mediates tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 (ICAM-1) expression and the adhesion of neutrophil in human umbilical vein endothelial cells
    • Bhunia AK, Arai T, Bulkley G, and Chatterjee S. Lactosylceramide mediates tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 (ICAM-1) expression and the adhesion of neutrophil in human umbilical vein endothelial cells. J Biol Chem 273: 34349-34357, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 34349-34357
    • Bhunia, A.K.1    Arai, T.2    Bulkley, G.3    Chatterjee, S.4
  • 7
    • 0030952830 scopus 로고    scopus 로고
    • Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells
    • Bhunia AK, Han H, Snowden A, and Chatterjee S. Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells. J Biol Chem 272: 15642-15649, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 15642-15649
    • Bhunia, A.K.1    Han, H.2    Snowden, A.3    Chatterjee, S.4
  • 8
    • 0035892633 scopus 로고    scopus 로고
    • Determination of ceramides and diglycerides by the diglyceride kinase assay
    • Bielawska A, Perry DK, and Hannun YA. Determination of ceramides and diglycerides by the diglyceride kinase assay. Anal Biochem 298: 141-150, 2001.
    • (2001) Anal Biochem , vol.298 , pp. 141-150
    • Bielawska, A.1    Perry, D.K.2    Hannun, Y.A.3
  • 10
    • 0031908071 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced dilatation of cerebral arterioles
    • Brian JE Jr and Faraci FM. Tumor necrosis factor-alpha-induced dilatation of cerebral arterioles. Stroke 29: 509-515, 1998.
    • (1998) Stroke , vol.29 , pp. 509-515
    • Brian J.E., Jr.1    Faraci, F.M.2
  • 11
    • 0025008449 scopus 로고
    • Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells
    • Busse R and Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett 275: 87-90, 1990.
    • (1990) FEBS Lett , vol.275 , pp. 87-90
    • Busse, R.1    Mulsch, A.2
  • 12
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H and Harrison DG. Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress. Circ Res 87: 840-844, 2000.
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 13
    • 0033136881 scopus 로고    scopus 로고
    • Therapeutic strategies to reduce TNF-α mediated cardiac contractile depression following ischemia and reperfusion
    • Cain BS, Harken AH, and Meldrum DR. Therapeutic strategies to reduce TNF-α mediated cardiac contractile depression following ischemia and reperfusion. J Mol Cell Cardiol 31: 931-947, 1999.
    • (1999) J Mol Cell Cardiol , vol.31 , pp. 931-947
    • Cain, B.S.1    Harken, A.H.2    Meldrum, D.R.3
  • 14
    • 0031694479 scopus 로고    scopus 로고
    • Sphingolipids in atherosclerosis and vascular biology
    • Chatterjee S. Sphingolipids in atherosclerosis and vascular biology. Arterioscler Thromb Vasc Biol 18: 1523-1533, 1998.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1523-1533
    • Chatterjee, S.1
  • 15
    • 0034969250 scopus 로고    scopus 로고
    • Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-α is mediated by ceramide
    • Corda S, Laplace C, Vicaut E, and Duranteau J. Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-α is mediated by ceramide. Am J Respir Cell Mol Biol 24: 762-768, 2001.
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 762-768
    • Corda, S.1    Laplace, C.2    Vicaut, E.3    Duranteau, J.4
  • 17
    • 0032445047 scopus 로고    scopus 로고
    • Control of microvascular resistance in physiological conditions and reperfusion
    • Defily DV. Control of microvascular resistance in physiological conditions and reperfusion. J Mol Cell Cardiol 30; 2547-2554, 1998.
    • (1998) J Mol Cell Cardiol , vol.30 , pp. 2547-2554
    • Defily, D.V.1
  • 18
    • 0034612304 scopus 로고    scopus 로고
    • Ceramide interaction with the respiratory chain of heart mitochondria
    • Di Paola M, Cocco T, and Lorusso M. Ceramide interaction with the respiratory chain of heart mitochondria. Biochemistry 39: 6660-6668, 2000.
    • (2000) Biochemistry , vol.39 , pp. 6660-6668
    • Di Paola, M.1    Cocco, T.2    Lorusso, M.3
  • 19
    • 0028108788 scopus 로고
    • Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor
    • Dobrowsky RT, Werner MH, Castellino AM, Chao MV, and Hannun YA. Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265: 1596-1599, 1994.
    • (1994) Science , vol.265 , pp. 1596-1599
    • Dobrowsky, R.T.1    Werner, M.H.2    Castellino, A.M.3    Chao, M.V.4    Hannun, Y.A.5
  • 20
    • 0031800520 scopus 로고    scopus 로고
    • Effects of tumour necrosis factor-α on the coronary circulation of the rat isolated perfused heart: A potential role for thromboxane A2 and sphingosine
    • Edmunds NJ and Woodward B. Effects of tumour necrosis factor-α on the coronary circulation of the rat isolated perfused heart: A potential role for thromboxane A2 and sphingosine. Br J Pharmacol 124: 493-498, 1998.
    • (1998) Br J Pharmacol , vol.124 , pp. 493-498
    • Edmunds, N.J.1    Woodward, B.2
  • 24
    • 1842330849 scopus 로고    scopus 로고
    • Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
    • Garcia-Ruiz C, Colell A, Mari M, Morales A, and Fernandez-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J Biol Chem 272: 11369-11377, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 11369-11377
    • Garcia-Ruiz, C.1    Colell, A.2    Mari, M.3    Morales, A.4    Fernandez-Checa, J.C.5
  • 25
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling KK, Sorescu D, and Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86: 494-501, 2000.
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 26
    • 0030198549 scopus 로고    scopus 로고
    • Tumor necrosis factor-α is released from the isolated heart undergoing ischemia and reperfusion
    • Gurevitch J, Frolkis I, Yuhas Y, Paz Y, Matsa M, Mohr R, and Yakirevich V. Tumor necrosis factor-α is released from the isolated heart undergoing ischemia and reperfusion. J Am Coll Cardiol 28: 247-252, 1996.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 247-252
    • Gurevitch, J.1    Frolkis, I.2    Yuhas, Y.3    Paz, Y.4    Matsa, M.5    Mohr, R.6    Yakirevich, V.7
  • 27
    • 0027994349 scopus 로고
    • The sphingomyelin cycle and the second messenger function of ceramide
    • Hannun YA. The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269: 3125-3128, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 3125-3128
    • Hannun, Y.A.1
  • 28
    • 0032540289 scopus 로고    scopus 로고
    • Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms
    • Harada-Shiba M, Kinoshita M, Kamido H, and Shimokado K. Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. J Biol Chem 273: 9681-9687, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 9681-9687
    • Harada-Shiba, M.1    Kinoshita, M.2    Kamido, H.3    Shimokado, K.4
  • 29
    • 0030711684 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of endothelial cell dysfunction
    • Harrison DG. Cellular and molecular mechanisms of endothelial cell dysfunction. J Clin Invest 100: 2153-2157, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 2153-2157
    • Harrison, D.G.1
  • 30
    • 0034604554 scopus 로고    scopus 로고
    • Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae
    • Hauck CR, Grassme H, Bock J, Jendrossek V, Ferlinz K, Meyer TF, and Gulbins E. Acid sphingomyelinase is involved in CEACAM receptor-mediated phagocytosis of Neisseria gonorrhoeae. FEBS Lett 478: 260-266, 2000.
    • (2000) FEBS Lett , vol.478 , pp. 260-266
    • Hauck, C.R.1    Grassme, H.2    Bock, J.3    Jendrossek, V.4    Ferlinz, K.5    Meyer, T.F.6    Gulbins, E.7
  • 31
    • 0034955810 scopus 로고    scopus 로고
    • The time course of tumor necrosis factor-α, inducible nitric oxide synthase and vascular endothelial growth factor expression in an experimental model of chronic myocardial infarction in rats
    • Heba G, Krzeminski T, Porc M, Grzyb J, Ratajska A, and Dembinska-Kiec A. The time course of tumor necrosis factor-α, inducible nitric oxide synthase and vascular endothelial growth factor expression in an experimental model of chronic myocardial infarction in rats. J Vasc Res 38: 288-300, 2001.
    • (2001) J Vasc Res , vol.38 , pp. 288-300
    • Heba, G.1    Krzeminski, T.2    Porc, M.3    Grzyb, J.4    Ratajska, A.5    Dembinska-Kiec, A.6
  • 32
    • 0032563652 scopus 로고    scopus 로고
    • LDLs impair vasomotor function of the coronary microcirculation: Role of superoxide anions
    • Hein TW and Kuo L. LDLs impair vasomotor function of the coronary microcirculation: Role of superoxide anions. Circ Res 83: 404-414, 1998.
    • (1998) Circ Res , vol.83 , pp. 404-414
    • Hein, T.W.1    Kuo, L.2
  • 33
    • 0034738011 scopus 로고    scopus 로고
    • Physiology and pathophysiology of sphingolipid metabolism and signaling
    • Huwiler A, Kolter T, Pfeilschifter J, and Sandhoff K. Physiology and pathophysiology of sphingolipid metabolism and signaling. Biochim Biophys Acta 1485: 63-99, 2000.
    • (2000) Biochim Biophys Acta , vol.1485 , pp. 63-99
    • Huwiler, A.1    Kolter, T.2    Pfeilschifter, J.3    Sandhoff, K.4
  • 34
    • 0031559598 scopus 로고    scopus 로고
    • Ceramide: A novel cell signaling mechanism for vasorelaxation
    • Johns DG, Osborn H, and Webb RC. Ceramide: A novel cell signaling mechanism for vasorelaxation. Biochem Biophys Res Commun 237: 95-97, 1997.
    • (1997) Biochem Biophys Res Commun , vol.237 , pp. 95-97
    • Johns, D.G.1    Osborn, H.2    Webb, R.C.3
  • 36
    • 0035026559 scopus 로고    scopus 로고
    • TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
    • Kim F, Gallis B, and Corson MA. TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells. Am J Physiol Cell Physiol 280: C1057-C1065, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Kim, F.1    Gallis, B.2    Corson, M.A.3
  • 37
    • 0026007737 scopus 로고
    • Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation
    • Kim MY, Linardic C, Obeid L, and Hannun YA. Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. J Biol Chem 266: 484-489, 1991.
    • (1991) J Biol Chem , vol.266 , pp. 484-489
    • Kim, M.Y.1    Linardic, C.2    Obeid, L.3    Hannun, Y.A.4
  • 38
    • 0028793499 scopus 로고
    • Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines
    • Klemm P, Warner TD, Corder R, and Vane JR. Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines. J Cardiovasc Pharmacol 26: S419-S421, 1995.
    • (1995) J Cardiovasc Pharmacol , vol.26
    • Klemm, P.1    Warner, T.D.2    Corder, R.3    Vane, J.R.4
  • 40
    • 0345713145 scopus 로고    scopus 로고
    • Involvement of sphingomyelinases in TNF signaling pathways
    • Kronke M. Involvement of sphingomyelinases in TNF signaling pathways. Chem Phys Lipids 102: 157-166, 1999.
    • (1999) Chem Phys Lipids , vol.102 , pp. 157-166
    • Kronke, M.1
  • 41
    • 0027510322 scopus 로고
    • Cytokines and growth factors in endothelial dysfunction
    • Lefer AM and Ma XL. Cytokines and growth factors in endothelial dysfunction. Crit Care Med 21: S9-S14, 1993.
    • (1993) Crit Care Med , vol.21
    • Lefer, A.M.1    Ma, X.L.2
  • 43
    • 0037040157 scopus 로고    scopus 로고
    • Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-α
    • Li JM, Mullen AM, Yun S, Wientjes F, Brouns GY, Thrasher AJ, and Shah AM. Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-α. Circ Res 90: 143-150, 2002.
    • (2002) Circ Res , vol.90 , pp. 143-150
    • Li, J.M.1    Mullen, A.M.2    Yun, S.3    Wientjes, F.4    Brouns, G.Y.5    Thrasher, A.J.6    Shah, A.M.7
  • 45
    • 0032742602 scopus 로고    scopus 로고
    • Sphingomyelinase assay using radiolabeled substrate
    • Liu B and Hannun YA. Sphingomyelinase assay using radiolabeled substrate. Methods Enzymol 311: 164-167, 1999.
    • (1999) Methods Enzymol , vol.311 , pp. 164-167
    • Liu, B.1    Hannun, Y.A.2
  • 46
    • 0026553107 scopus 로고
    • Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction
    • Liu SF, Dewar A, Crawley DE, Barnes PJ, and Evans TW. Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction. J Appl Physiol 72: 1044-1049, 1992.
    • (1992) J Appl Physiol , vol.72 , pp. 1044-1049
    • Liu, S.F.1    Dewar, A.2    Crawley, D.E.3    Barnes, P.J.4    Evans, T.W.5
  • 47
    • 0034964508 scopus 로고    scopus 로고
    • TNF signaling in vascular endothelial cells
    • Madge LA and Pober JS. TNF signaling in vascular endothelial cells. Exp Mol Pathol 70: 317-325, 2001.
    • (2001) Exp Mol Pathol , vol.70 , pp. 317-325
    • Madge, L.A.1    Pober, J.S.2
  • 49
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
    • Mathias S, Younes A, Kan CC, Orlow I, Joseph C, and Kolesnick RN. Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta. Science 259: 519-522, 1993.
    • (1993) Science , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.C.3    Orlow, I.4    Joseph, C.5    Kolesnick, R.N.6
  • 50
    • 0024549099 scopus 로고
    • Circulating tumour necrosis factor-alpha (cachectin) in myocardial infarction
    • Maury CP and Teppo AM. Circulating tumour necrosis factor-alpha (cachectin) in myocardial infarction. J Intern Med 225: 333-336, 1989.
    • (1989) J Intern Med , vol.225 , pp. 333-336
    • Maury, C.P.1    Teppo, A.M.2
  • 53
    • 0030010965 scopus 로고    scopus 로고
    • Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades
    • Modur V, Zimmerman GA, Prescott SM, and McIntyre TM. Endothelial cell inflammatory responses to tumor necrosis factor alpha. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. J Biol Chem 271: 13094-13102, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 13094-13102
    • Modur, V.1    Zimmerman, G.A.2    Prescott, S.M.3    McIntyre, T.M.4
  • 54
    • 0029896139 scopus 로고    scopus 로고
    • Effects of sphingomyelinase and sphingosine on arterial vasomotor regulation
    • Murohara T, Kugiyama K, Ohgushi M, Sugiyama S, Ohta Y, and Yasue H. Effects of sphingomyelinase and sphingosine on arterial vasomotor regulation. J Lipid Res 37: 1601-1608, 1996.
    • (1996) J Lipid Res , vol.37 , pp. 1601-1608
    • Murohara, T.1    Kugiyama, K.2    Ohgushi, M.3    Sugiyama, S.4    Ohta, Y.5    Yasue, H.6
  • 55
    • 0033796139 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-alpha on basal and stimulated endothelium-dependent vasomotion in human resistance vessel
    • Nakamura M, Yoshida H, Arakawa N, Saitoh S, Satoh M, and Hiramori K. Effects of tumor necrosis factor-alpha on basal and stimulated endothelium-dependent vasomotion in human resistance vessel. J Cardiovasc Pharmacol 36: 487-492, 2000.
    • (2000) J Cardiovasc Pharmacol , vol.36 , pp. 487-492
    • Nakamura, M.1    Yoshida, H.2    Arakawa, N.3    Saitoh, S.4    Satoh, M.5    Hiramori, K.6
  • 56
    • 0032445275 scopus 로고    scopus 로고
    • Lipid second messengers derived from glyerolipids and sphingolipids, and their role in smooth muscle function
    • Ohanian J, Liu G, Ohanian V, and Heagerty AM. Lipid second messengers derived from glyerolipids and sphingolipids, and their role in smooth muscle function. Acta Physiol Scand 164: 533-548, 1998.
    • (1998) Acta Physiol Scand , vol.164 , pp. 533-548
    • Ohanian, J.1    Liu, G.2    Ohanian, V.3    Heagerty, A.M.4
  • 57
    • 0025003424 scopus 로고
    • Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation
    • Okazaki T, Bielawska A, Bell RM, and Hannun YA. Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J Biol Chem 265: 15823- 15831, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 15823-15831
    • Okazaki, T.1    Bielawska, A.2    Bell, R.M.3    Hannun, Y.A.4
  • 58
    • 0033790309 scopus 로고    scopus 로고
    • Quantitative determination of ceramide using diglyceride kinase
    • Perry DK, Bielawska A, and Hannun YA. Quantitative determination of ceramide using diglyceride kinase. Methods Enzymol 312: 22-31, 2000.
    • (2000) Methods Enzymol , vol.312 , pp. 22-31
    • Perry, D.K.1    Bielawska, A.2    Hannun, Y.A.3
  • 59
    • 0028076002 scopus 로고
    • The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction
    • Schutze S, Machleidt T, and Kronke M. The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction. J Leukoc Biol 56: 533-541, 1994.
    • (1994) J Leukoc Biol , vol.56 , pp. 533-541
    • Schutze, S.1    Machleidt, T.2    Kronke, M.3
  • 61
    • 0028010239 scopus 로고
    • Administration of tumor necrosis factor-α in vivo depresses endothelium-dependent relaxation
    • Wang P, Ba ZF, and Chaudry IH. Administration of tumor necrosis factor-α in vivo depresses endothelium-dependent relaxation. Am J Physiol Heart Circ Physiol 266: H2535-H2541, 1994.
    • (1994) Am J Physiol Heart Circ Physiol , vol.266
    • Wang, P.1    Ba, Z.F.2    Chaudry, I.H.3
  • 62
    • 0028108015 scopus 로고
    • Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
    • Wiegmann K, Schutze S, Machleidt T, Witte D, and Kronke M. Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78: 1005-1015, 1994.
    • (1994) Cell , vol.78 , pp. 1005-1015
    • Wiegmann, K.1    Schutze, S.2    Machleidt, T.3    Witte, D.4    Kronke, M.5
  • 64
    • 0032568836 scopus 로고    scopus 로고
    • Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death
    • Xu J, Yeh CH, Chen S, He L, Sensi SL, Canzoniero LM, Choi DW, and Hsu CY. Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death. J Biol Chem 273: 16521-16526, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 16521-16526
    • Xu, J.1    Yeh, C.H.2    Chen, S.3    He, L.4    Sensi, S.L.5    Canzoniero, L.M.6    Choi, D.W.7    Hsu, C.Y.8
  • 66
    • 0035105095 scopus 로고    scopus 로고
    • ADP-ribose dilates bovine coronary small arteries through apyrase- and 5′-nucleotidase-mediated metabolism
    • Zhang DX, Zou AP, and Li PL. ADP-ribose dilates bovine coronary small arteries through apyrase- and 5′-nucleotidase-mediated metabolism. J Vasc Res 38: 64-72, 2001.
    • (2001) J Vasc Res , vol.38 , pp. 64-72
    • Zhang, D.X.1    Zou, A.P.2    Li, P.L.3
  • 67
    • 0035957592 scopus 로고    scopus 로고
    • Ceramide reduces endothelium-dependent vasorelaxation by increasing superoxide production in small bovine coronary arteries
    • Zhang DX, Zou AP, and Li PL. Ceramide reduces endothelium-dependent vasorelaxation by increasing superoxide production in small bovine coronary arteries. Circ Res 88: 824-831, 2001.
    • (2001) Circ Res , vol.88 , pp. 824-831
    • Zhang, D.X.1    Zou, A.P.2    Li, P.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.