Intermolecular β-strand networks avoid hub residues and favor low interconnectedness: A potential protection mechanism against chain dissociation upon mutation

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Feverati, Giovanni ^a   Achoch, Mounia ^a   Vuillon, Laurent ^a   Lesieur, Claire ^b  

^a UNIVERSITÉ DE SAVOIE   (France)

^b UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PROTEIN P53; AMINO ACID; AMYLOID; PROTEIN BINDING; TP53 PROTEIN, HUMAN;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ANTIGEN ANTIBODY REACTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTALLOGRAPHY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR EVOLUTION; OLIGOMERIZATION; PLASTICITY; PROTEIN CONFORMATION; PROTEIN INTERACTION; ALGORITHM; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; MUTATION; PROTEIN DATABASE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STATISTICAL MODEL;

ALGORITHMS; AMINO ACIDS; AMYLOID; COMPUTATIONAL BIOLOGY; DATABASES, PROTEIN; HUMANS; MODELS, MOLECULAR; MODELS, STATISTICAL; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84899633630     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094745     Document Type: Article

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